{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=open+surgery&page=13", "query": { "intervention": "open surgery", "page": 13 }, "page_size": 10 }, "pagination": { "page": 13, "page_size": 10, "total_count": 1549, "total_pages": 155, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=open+surgery&page=14&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=open+surgery&page=12&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-23T14:34:56.625Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03452072", "title": "Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Wound of Skin", "Wound Heal", "Wound Open", "Surgical Wound" ], "interventions": [ { "name": "0.25% Timolol gel with paraffin gauze dressings", "type": "DRUG" }, { "name": "Vaseline dressing", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 87, "start_date": "2018-08-20", "completion_date": "2021-06-30", "has_results": true, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03452072" }, { "nct_id": "NCT05219695", "title": "Medical Imaging and Focused Ultrasound Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Fibroadenoma", "Breast Cancer Stage I" ], "interventions": [ { "name": "Harmonic motion imaging guided focused ultrasound (HMIgFUS)", "type": "PROCEDURE" }, { "name": "Microbubble-mediated Low Intensity Focused Ultrasound (LIFU)", "type": "PROCEDURE" }, { "name": "Microbubbles", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 82, "start_date": "2022-01-19", "completion_date": "2031-05", "has_results": false, "last_update_posted_date": "2026-08-13", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05219695" }, { "nct_id": "NCT01560377", "title": "Perfusion Assessment in Laparoscopic Left Anterior Resection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Rectal Cancer", "Colon Cancer", "Crohn's Disease", "Polyp", "Procidentia", "Diverticulitis" ], "interventions": [ { "name": "PINPOINT Endoscopic Fluorescence Imaging System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Novadaq Technologies ULC, now a part of Stryker", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 147, "start_date": "2012-05", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2018-12-11", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 11, "location_summary": "Los Angeles, California • Orange, California • San Diego, California + 7 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Weston", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01560377" }, { "nct_id": "NCT01920594", "title": "Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Surgical Procedures" ], "interventions": [ { "name": "GSK1278863", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 57, "start_date": "2013-10-31", "completion_date": "2014-10-08", "has_results": true, "last_update_posted_date": "2017-12-07", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 13, "location_summary": "Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 10 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01920594" }, { "nct_id": "NCT01682746", "title": "Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Brain Tumor, Recurrent" ], "interventions": [ { "name": "Photofrin (porfimer sodium) & photodynamic therapy.", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Harry T Whelan, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "18 Years", "sex": "ALL", "summary": "6 Months to 18 Years" }, "enrollment_count": 5, "start_date": "2013-03", "completion_date": "2018-06-29", "has_results": false, "last_update_posted_date": "2019-02-25", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 1, "location_summary": "Wauwatosa, Wisconsin", "locations": [ { "city": "Wauwatosa", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01682746" }, { "nct_id": "NCT00815191", "title": "Comparison of Vital HEAT (vH2) Temperature Management System to Upper-body Forced-air Warming", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Surgery" ], "interventions": [ { "name": "a forced-air warming cover", "type": "DEVICE" }, { "name": "vital HEAT (vH2) Temperature Management System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 73, "start_date": "2008-01", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2016-07-18", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00815191" }, { "nct_id": "NCT04462523", "title": "DEXTENZA for the Treatment of Postoperative Pain and Inflammation Following Vitreo-retinal Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Vitreo-Retinal Surgery" ], "interventions": [ { "name": "Dextenza 0.4Mg Ophthalmic Insert", "type": "DRUG" }, { "name": "Topical Prednisolone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Patrick R. Oellers, MD", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 40, "start_date": "2020-01-03", "completion_date": "2022-03-31", "has_results": false, "last_update_posted_date": "2023-06-15", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 1, "location_summary": "Liverpool, New York", "locations": [ { "city": "Liverpool", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04462523" }, { "nct_id": "NCT05654103", "title": "Comparing Surgical and Endovascular Arteriovenous Fistula Creation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "End Stage Renal Disease on Dialysis" ], "interventions": [ { "name": "endoAVF", "type": "DEVICE" }, { "name": "surgAVF", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "PROCEDURE" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 90, "start_date": "2024-11-20", "completion_date": "2027-01", "has_results": false, "last_update_posted_date": "2026-08-10", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 2, "location_summary": "Los Angeles, California • Pittsburgh, Pennsylvania", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05654103" }, { "nct_id": "NCT04452188", "title": "Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypoplastic Left Heart Syndrome", "Total Anomalous Pulmonary Venous Return", "Truncus Arteriosus", "Pulmonary Atresia With Ventricular Septal Defect", "Transposition of the Great Arteries", "Double Outlet Right Ventricle, Subpulmonary VSD", "Tetralogy of Fallot", "Double Outlet Right Ventricle With Subaortic Ventricular Septal Defect and Pulmonary Stenosis", "Cardiopulmonary Bypass" ], "interventions": [ { "name": "Normoxia (with controlled re-oxygenation)", "type": "OTHER" }, { "name": "Standard of care ventilation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "29 Days", "sex": "ALL", "summary": "Up to 29 Days" }, "enrollment_count": 29, "start_date": "2021-01-18", "completion_date": "2023-04-20", "has_results": true, "last_update_posted_date": "2024-06-18", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT04452188" }, { "nct_id": "NCT03112603", "title": "A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Graft-versus-host Disease (GVHD)" ], "interventions": [ { "name": "Ruxolitinib", "type": "DRUG" }, { "name": "Extracorporeal photopheresis (ECP)", "type": "DRUG" }, { "name": "Low-dose methotrexate (MTX)", "type": "DRUG" }, { "name": "Mycophenolate mofetil (MMF)", "type": "DRUG" }, { "name": "mechanistic Target of Rapamycin (mTOR) inhibitors (everolimus or sirolimus)", "type": "DRUG" }, { "name": "Infliximab", "type": "DRUG" }, { "name": "Rituximab", "type": "DRUG" }, { "name": "Pentostatin", "type": "DRUG" }, { "name": "Imatinib", "type": "DRUG" }, { "name": "Ibrutinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Incyte Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 330, "start_date": "2017-06-29", "completion_date": "2022-12-15", "has_results": true, "last_update_posted_date": "2025-08-12", "last_synced_at": "2026-10-23T14:34:56.625Z", "location_count": 38, "location_summary": "Tucson, Arizona • Duarte, California • La Jolla, California + 28 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03112603" } ] }