{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=opiates&page=14", "query": { "intervention": "opiates", "page": 14 }, "page_size": 10 }, "pagination": { "page": 14, "page_size": 10, "total_count": 1428, "total_pages": 143, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=opiates&page=15&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=opiates&page=13&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-31T00:38:57.246Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01571362", "title": "A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Pain", "Low Back Pain", "Analgesia" ], "interventions": [ { "name": "ALO-02", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 410, "start_date": "2012-06", "completion_date": "2013-06", "has_results": true, "last_update_posted_date": "2017-04-04", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 52, "location_summary": "Mobile, Alabama • Goodyear, Arizona • Phoenix, Arizona + 38 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Goodyear", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01571362" }, { "nct_id": "NCT00316277", "title": "Prescription Opioid Addiction Treatment Study (POATS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Opiate Dependence", "Substance-related Disorders", "Opioid-related Disorders" ], "interventions": [ { "name": "Standard Medical Management (SMM) of Prescription Opiate Abuse", "type": "BEHAVIORAL" }, { "name": "Enhanced Medical Management (EMM) of Prescription Opiate Abuse", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Mclean Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 653, "start_date": "2006-05", "completion_date": "2013-01", "has_results": true, "last_update_posted_date": "2013-02-06", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 12, "location_summary": "Los Angeles, California • San Francisco, California • Lawrenceburg, Indiana + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Lawrenceburg", "state": "Indiana" }, { "city": "Belmont", "state": "Massachusetts" }, { "city": "Glen Oaks", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00316277" }, { "nct_id": "NCT00338962", "title": "Naltrexone & SSRI in Alcoholics With Depression/PTSD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alcoholism", "Depression", "PTSD" ], "interventions": [ { "name": "paroxetine", "type": "DRUG" }, { "name": "desipramine", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "21 Years to 75 Years" }, "enrollment_count": 88, "start_date": "2001-10", "completion_date": "2015-07", "has_results": true, "last_update_posted_date": "2016-02-05", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 1, "location_summary": "West Haven, Connecticut", "locations": [ { "city": "West Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00338962" }, { "nct_id": "NCT01015066", "title": "Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Opiate Addiction" ], "interventions": [ { "name": "Buprenorphine/naloxone", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "State University of New York at Buffalo", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "16 Years to 25 Years" }, "enrollment_count": 0, "start_date": "2009-11", "completion_date": "2014-06", "has_results": false, "last_update_posted_date": "2014-06-10", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01015066" }, { "nct_id": "NCT03681769", "title": "Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Chronic Pain", "Opiate Dependence", "Lower Back Pain" ], "interventions": [ { "name": "iTBS to the left dlPFC", "type": "DEVICE" }, { "name": "Sham iTBS to the left dlPFC", "type": "DEVICE" }, { "name": "cTBS to the mPFC", "type": "DEVICE" }, { "name": "Sham cTBS to the mPFC", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 24, "start_date": "2019-02-22", "completion_date": "2021-03-19", "has_results": true, "last_update_posted_date": "2023-02-10", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03681769" }, { "nct_id": "NCT00818493", "title": "Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Q8003 (morphine sulfate and oxycodone hydrochloride)", "type": "DRUG" }, { "name": "Low dose Q8003 (morphine sulfate and oxycodone hydrochloride)", "type": "DRUG" }, { "name": "Percocet (oxycodone and acetaminophen)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "QRxPharma Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 44, "start_date": "2009-02", "completion_date": "2009-07", "has_results": false, "last_update_posted_date": "2012-05-17", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 4, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Royal Oak, Michigan + 1 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Royal Oak", "state": "Michigan" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00818493" }, { "nct_id": "NCT01546948", "title": "Intraoperative Opioids and Postoperative Recovery After Hepatobiliary or Foregut Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Methadone", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Endeavor Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 60, "start_date": "2011-08", "completion_date": "2018-06", "has_results": false, "last_update_posted_date": "2021-12-21", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 1, "location_summary": "Evanston, Illinois", "locations": [ { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01546948" }, { "nct_id": "NCT02321319", "title": "Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Pain" ], "interventions": [ { "name": "Hydromorphone HCl ER Tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mallinckrodt", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 5, "start_date": "2017-03-11", "completion_date": "2019-02-04", "has_results": true, "last_update_posted_date": "2020-05-21", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 3, "location_summary": "Miami, Florida • Tampa, Florida", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02321319" }, { "nct_id": "NCT00069550", "title": "Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rett Syndrome" ], "interventions": [ { "name": "dextromethorphan", "type": "DRUG" }, { "name": "donepezil hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "15 Years", "sex": "ALL", "summary": "1 Year to 15 Years" }, "enrollment_count": 90, "start_date": "2004-09", "completion_date": "2008-06", "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00069550" }, { "nct_id": "NCT03511118", "title": "Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lactating Women on Select DOI", "Breastfed Infants of Mothers on Select DOI" ], "interventions": [ { "name": "Tranexamic acid (TXA)", "type": "DRUG" }, { "name": "labetalol", "type": "DRUG" }, { "name": "metformin", "type": "DRUG" }, { "name": "nifedipine", "type": "DRUG" }, { "name": "clindamycin", "type": "DRUG" }, { "name": "oxycodone", "type": "DRUG" }, { "name": "azithromycin", "type": "DRUG" }, { "name": "escitalopram", "type": "DRUG" }, { "name": "sertraline", "type": "DRUG" }, { "name": "ondansetron", "type": "DRUG" }, { "name": "Ciprofloxacin", "type": "DRUG" }, { "name": "Doxycycline", "type": "DRUG" }, { "name": "Levofloxacin", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" }, { "name": "Sumatriptan", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Cyclobenzaprine", "type": "DRUG" }, { "name": "Furosemide", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Hydroxyurea", "type": "DRUG" }, { "name": "Rosuvastatin", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Trazodone", "type": "DRUG" }, { "name": "Valganciclovir", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Verapamil", "type": "DRUG" }, { "name": "Remdesivir", "type": "DRUG" }, { "name": "Anakinra", "type": "DRUG" }, { "name": "Tocilizumab", "type": "DRUG" }, { "name": "Fluvoxamine", "type": "DRUG" }, { "name": "Amoxicillin", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Hydrocodone", "type": "DRUG" }, { "name": "Levetiracetam", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Buprenorphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1600, "start_date": "2018-10-04", "completion_date": "2028-07-31", "has_results": false, "last_update_posted_date": "2026-07-29", "last_synced_at": "2026-10-31T00:38:57.246Z", "location_count": 20, "location_summary": "La Jolla, California • Loma Linda, California • Chicago, Illinois + 15 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03511118" } ] }