{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=opiates&page=46", "query": { "intervention": "opiates", "page": 46 }, "page_size": 10 }, "pagination": { "page": 46, "page_size": 10, "total_count": 1430, "total_pages": 143, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=opiates&page=47&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=opiates&page=45&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-06T17:41:51.765Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02625181", "title": "Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Nausea and Vomiting" ], "interventions": [ { "name": "Automated recommendation at the start of the case", "type": "PROCEDURE" }, { "name": "Automated notification at the start of surgery", "type": "PROCEDURE" }, { "name": "Preoperative recommendations: by email", "type": "PROCEDURE" }, { "name": "Automated notification at the end of surgery", "type": "PROCEDURE" }, { "name": "Anesthesia Information Management System (AIMS)", "type": "DEVICE" }, { "name": "Perioperative Data Warehouse (PDW)", "type": "DEVICE" }, { "name": "General anesthesia", "type": "PROCEDURE" }, { "name": "Elective surgery", "type": "PROCEDURE" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Isoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" }, { "name": "Scopolamine", "type": "DRUG" }, { "name": "Droperidol", "type": "DRUG" }, { "name": "Haloperidol", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Promethazine", "type": "DRUG" }, { "name": "Meclizine", "type": "DRUG" }, { "name": "Aprepitant", "type": "DRUG" }, { "name": "Metoclopramide", "type": "DRUG" }, { "name": "Fentanyl", "type": "DRUG" }, { "name": "Sufentanil", "type": "DRUG" }, { "name": "Alfentanil", "type": "DRUG" }, { "name": "Remifentanil", "type": "DRUG" }, { "name": "Morphine", "type": "DRUG" }, { "name": "Meperidine", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Methadone", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "Oxymorphone", "type": "DRUG" }, { "name": "Hydrocodone", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Granisetron", "type": "DRUG" }, { "name": "Dolasetron mesylate", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Tropisetron", "type": "DRUG" }, { "name": "Ramosetron", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27034, "start_date": "2016-07", "completion_date": "2017-11-30", "has_results": true, "last_update_posted_date": "2019-03-07", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02625181" }, { "nct_id": "NCT01903005", "title": "Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Opioid Dependence, on Agonist Therapy" ], "interventions": [ { "name": "Higher bioavailability BNX sublingual tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Orexo AB", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 668, "start_date": "2013-07", "completion_date": "2014-09", "has_results": true, "last_update_posted_date": "2015-10-28", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 28, "location_summary": "Jefferson County, Alabama • Marion County, Alabama • Winston County, Alabama + 25 more", "locations": [ { "city": "Jefferson County", "state": "Alabama" }, { "city": "Marion County", "state": "Alabama" }, { "city": "Winston County", "state": "Alabama" }, { "city": "Maricopa County", "state": "Arizona" }, { "city": "Los Angeles County", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01903005" }, { "nct_id": "NCT01225991", "title": "Milnacipran for Treatment of Pain in Older Adults With Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Milnacipran", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 18, "start_date": "2010-11", "completion_date": "2013-06", "has_results": true, "last_update_posted_date": "2018-03-29", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01225991" }, { "nct_id": "NCT00183196", "title": "Effectiveness of Gabapentin When Used With Naltrexone to Treat Alcohol Dependence Compared to Placebo and Naltrexone Alone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alcohol Dependence" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Naltrexone plus Gabapentin", "type": "DRUG" }, { "name": "Inactive Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 150, "start_date": "2003-01", "completion_date": "2009-06", "has_results": true, "last_update_posted_date": "2018-06-07", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00183196" }, { "nct_id": "NCT00129246", "title": "Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Smoking", "Nicotine Dependence" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2004-12", "completion_date": "2005-12", "has_results": true, "last_update_posted_date": "2020-12-03", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00129246" }, { "nct_id": "NCT01651325", "title": "Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Pharmacokinetics of Isavuconazole", "Pharmacokinetics of Dextromethorphan", "Healthy Adult Volunteers" ], "interventions": [ { "name": "Isavuconazole", "type": "DRUG" }, { "name": "dextromethorphan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Astellas Pharma Global Development, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 24, "start_date": "2012-05", "completion_date": "2012-05", "has_results": false, "last_update_posted_date": "2015-02-23", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01651325" }, { "nct_id": "NCT03922646", "title": "Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Opioid-use Disorder", "Amphetamine Use Disorders" ], "interventions": [ { "name": "Neurocognitive Empowerment for Addiction Treatment (NEAT)", "type": "BEHAVIORAL" }, { "name": "Active Control", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Laureate Institute for Brain Research, Inc.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 104, "start_date": "2019-03-06", "completion_date": "2023-05-12", "has_results": false, "last_update_posted_date": "2023-08-28", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Tulsa, Oklahoma", "locations": [ { "city": "Tulsa", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT03922646" }, { "nct_id": "NCT02541396", "title": "A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "Wafermine", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "iX Biopharma Ltd.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 72, "start_date": "2015-10", "completion_date": "2015-12", "has_results": false, "last_update_posted_date": "2016-02-23", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02541396" }, { "nct_id": "NCT04188418", "title": "Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hematopoietic and Lymphoid Cell Neoplasm", "Malignant Solid Neoplasm" ], "interventions": [ { "name": "Fentanyl Citrate Buccal Tablet", "type": "DRUG" }, { "name": "Morphine", "type": "DRUG" }, { "name": "Physical Performance Testing", "type": "OTHER" }, { "name": "Placebo Administration", "type": "OTHER" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 150, "start_date": "2020-10-23", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-08-11", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04188418" }, { "nct_id": "NCT02432456", "title": "Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Wounds and Injuries", "Rib Fractures" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Intercostal Nerve Block", "type": "PROCEDURE" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Pantoprazole", "type": "DRUG" }, { "name": "Methocarbamol", "type": "DRUG" }, { "name": "Opioid", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 153, "start_date": "2015-09", "completion_date": "2018-08", "has_results": true, "last_update_posted_date": "2020-02-05", "last_synced_at": "2026-11-06T17:41:51.765Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT02432456" } ] }