{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=or+Metformin+HCl+alone&page=2", "query": { "intervention": "or Metformin HCl alone", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 108, "total_pages": 11, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=or+Metformin+HCl+alone&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=or+Metformin+HCl+alone&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-08T02:48:24.762Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02365233", "title": "Fatty Liver Study in Patients With Type II Diabetes", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Type II Diabetes", "Nonalcoholic Fatty Liver" ], "interventions": [ { "name": "DPP4 inhibitor", "type": "DRUG" }, { "name": "Pioglitazone", "type": "DRUG" }, { "name": "Lantus insulin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Medical Branch, Galveston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 5, "start_date": "2013-05-01", "completion_date": "2016-12-31", "has_results": true, "last_update_posted_date": "2018-07-31", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 1, "location_summary": "Galveston, Texas", "locations": [ { "city": "Galveston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02365233" }, { "nct_id": "NCT03893422", "title": "Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "WB-010", "type": "OTHER" }, { "name": "WB-011", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Pendulum Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 76, "start_date": "2017-10-22", "completion_date": "2018-09-14", "has_results": false, "last_update_posted_date": "2020-02-27", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 5, "location_summary": "Torrance, California • Tustin, California • Youngstown, Ohio + 2 more", "locations": [ { "city": "Torrance", "state": "California" }, { "city": "Tustin", "state": "California" }, { "city": "Youngstown", "state": "Ohio" }, { "city": "Mt. Pleasant", "state": "South Carolina" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03893422" }, { "nct_id": "NCT01434186", "title": "A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Placebo matching with Saxagliptin", "type": "DRUG" }, { "name": "Metformin IR", "type": "DRUG" }, { "name": "Metformin XR", "type": "DRUG" }, { "name": "Saxagliptin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 32, "start_date": "2012-05", "completion_date": "2016-04", "has_results": true, "last_update_posted_date": "2017-04-18", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 7, "location_summary": "Los Angeles, California • Tallahassee, Florida • Dearborn, Michigan + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Tallahassee", "state": "Florida" }, { "city": "Dearborn", "state": "Michigan" }, { "city": "Saint Paul", "state": "Minnesota" }, { "city": "Mineola", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01434186" }, { "nct_id": "NCT00672464", "title": "Cardio Risk of Acute Schizophrenia Olanzapine Duke", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder" ], "interventions": [ { "name": "Olanzapine", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" }, { "name": "Simvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 0, "start_date": "2008-04", "completion_date": "2010-02", "has_results": false, "last_update_posted_date": "2014-07-31", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 2, "location_summary": "Butner, North Carolina • Durham, North Carolina", "locations": [ { "city": "Butner", "state": "North Carolina" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00672464" }, { "nct_id": "NCT01023581", "title": "Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Alogliptin", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" }, { "name": "Alogliptin Placebo", "type": "DRUG" }, { "name": "Metformin Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 784, "start_date": "2009-11", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2013-03-26", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 109, "location_summary": "Dothan, Alabama • Muscle Shoals, Alabama • Pell City, Alabama + 106 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Pell City", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01023581" }, { "nct_id": "NCT02419612", "title": "A 52-week International, Multicenter Trial With a Long -Term Extension to Evaluate Saxagliptin With Dapagliflozin in Combination With Metformin Compared to Glimepiride in Combination With Metformin in Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes" ], "interventions": [ { "name": "Saxagliptin", "type": "DRUG" }, { "name": "Dapagliflozin", "type": "DRUG" }, { "name": "Glimepiride", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 444, "start_date": "2015-08-14", "completion_date": "2019-09-18", "has_results": true, "last_update_posted_date": "2020-06-23", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 22, "location_summary": "Birmingham, Alabama • Chandler, Arizona • Tempe, Arizona + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Huntington Park", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02419612" }, { "nct_id": "NCT00894322", "title": "A Study to Examine the Pharmacokinetics, Tolerability, Safety and Efficacy of Exenatide Once Weekly Suspension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "exenatide once weekly", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "19 Years to 75 Years" }, "enrollment_count": 65, "start_date": "2009-04", "completion_date": "2009-08", "has_results": true, "last_update_posted_date": "2015-09-18", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 1, "location_summary": "Lincoln, Nebraska", "locations": [ { "city": "Lincoln", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT00894322" }, { "nct_id": "NCT05365451", "title": "Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Interaction", "Endogenous Biomarkers" ], "interventions": [ { "name": "MetFORMIN Oral Solution", "type": "DRUG" }, { "name": "Cimetidine 400 MG", "type": "DRUG" }, { "name": "Furosemide Oral Liquid Product", "type": "DRUG" }, { "name": "Probenecid 500 MG", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 16, "start_date": "2022-04-11", "completion_date": "2023-07-22", "has_results": true, "last_update_posted_date": "2025-08-08", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 1, "location_summary": "Spokane, Washington", "locations": [ { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT05365451" }, { "nct_id": "NCT00332488", "title": "Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Technosphere Insulin", "type": "DRUG" }, { "name": "Metformin & Secretagogues", "type": "DRUG" }, { "name": "Technosphere Insulin & Metformin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mannkind Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 547, "start_date": "2004-12", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-10-16", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 43, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Chula Vista, California + 25 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00332488" }, { "nct_id": "NCT00929539", "title": "Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type II Diabetes Mellitus" ], "interventions": [ { "name": "JTT-130", "type": "DRUG" }, { "name": "JTT-130 Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Akros Pharma Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 496, "start_date": "2009-06", "completion_date": "2010-07", "has_results": false, "last_update_posted_date": "2013-02-04", "last_synced_at": "2026-10-08T02:48:24.762Z", "location_count": 48, "location_summary": "Birmingham, Alabama • Muscle Shoals, Alabama • Scottsboro, Alabama + 45 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Scottsboro", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Encino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00929539" } ] }