{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=orthodontia&page=2",
    "query": {
      "intervention": "orthodontia",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=orthodontia&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T18:04:29.827Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03299023",
      "title": "The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Orthodontic Tooth Movement",
        "Apnea",
        "Sleep Disordered Breathing"
      ],
      "interventions": [
        {
          "name": "Medibyte Portable Monitor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Harvard School of Dental Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2017-01-20",
      "completion_date": "2019-06-10",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03299023"
    },
    {
      "nct_id": "NCT07091422",
      "title": "A Split-Mouth Clinical Trial Evaluating the Bond Failure Rate of a New Etch-Free Orthodontic Adhesive",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bracket Bonding",
        "Orthodontic Treatment",
        "Dental Adhesives/Restorations Performance",
        "White Spot Lesion of Tooth"
      ],
      "interventions": [
        {
          "name": "Etch-Free Adhesive",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Etch-and-Bond Adhesive",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-11-05",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07091422"
    },
    {
      "nct_id": "NCT02603289",
      "title": "One Week Aligner Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Invisalign",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Align Technology, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 287,
      "start_date": "2015-09",
      "completion_date": "2020-08",
      "has_results": false,
      "last_update_posted_date": "2020-10-20",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 23,
      "location_summary": "Livermore, California • Napa, California • San Francisco, California + 20 more",
      "locations": [
        {
          "city": "Livermore",
          "state": "California"
        },
        {
          "city": "Napa",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "San Ramon",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02603289"
    },
    {
      "nct_id": "NCT05905224",
      "title": "Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthodontic Tooth Movement"
      ],
      "interventions": [
        {
          "name": "Invisalign 7-day wear protocol",
          "type": "DEVICE"
        },
        {
          "name": "Invisalign 3-day wear protocol",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-10-30",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05905224"
    },
    {
      "nct_id": "NCT03333876",
      "title": "In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Snoring"
      ],
      "interventions": [
        {
          "name": "Nasal Dilator",
          "type": "DEVICE"
        },
        {
          "name": "Mandibular Advancement",
          "type": "DEVICE"
        },
        {
          "name": "Positional Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Respironics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 58,
      "start_date": "2017-10-09",
      "completion_date": "2017-12-03",
      "has_results": true,
      "last_update_posted_date": "2019-02-15",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Murrysville, Pennsylvania",
      "locations": [
        {
          "city": "Murrysville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03333876"
    },
    {
      "nct_id": "NCT06573996",
      "title": "The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthodontic Appliance",
        "Pain",
        "Transcutaneous Electric Nerve Stimulation",
        "Orthodontic Appliance Complication"
      ],
      "interventions": [
        {
          "name": "Active TENS Device",
          "type": "DEVICE"
        },
        {
          "name": "Intervention 2: Placebo/Sham Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of the Pacific",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2024-09-16",
      "completion_date": "2029-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06573996"
    },
    {
      "nct_id": "NCT04815564",
      "title": "Clear Aligners for the Treatment of Dental Malocclusion in OI",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteogenesis Imperfecta"
      ],
      "interventions": [
        {
          "name": "Invisalign",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "12 Years to 40 Years"
      },
      "enrollment_count": 57,
      "start_date": "2022-08-01",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Bethesda, Maryland",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04815564"
    },
    {
      "nct_id": "NCT03653143",
      "title": "JASPER Intervention in Down Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Down Syndrome, Trisomy 21"
      ],
      "interventions": [
        {
          "name": "JASPER",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "48 Months",
        "sex": "ALL",
        "summary": "24 Months to 48 Months"
      },
      "enrollment_count": 12,
      "start_date": "2018-12-01",
      "completion_date": "2021-07-31",
      "has_results": false,
      "last_update_posted_date": "2022-01-18",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03653143"
    },
    {
      "nct_id": "NCT04528134",
      "title": "Orthodontic Varnish Microbiology Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries",
        "Dental Plaque",
        "Dental White Spot"
      ],
      "interventions": [
        {
          "name": "Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish",
          "type": "DEVICE"
        },
        {
          "name": "5% Sodium Fluoride Varnish",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "27 Years",
        "sex": "ALL",
        "summary": "12 Years to 27 Years"
      },
      "enrollment_count": 38,
      "start_date": "2022-02-07",
      "completion_date": "2025-07-01",
      "has_results": true,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04528134"
    },
    {
      "nct_id": "NCT04560478",
      "title": "Comparing Fluoride Varnish and Sealant to Prevent White Spots in Orthodontic Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "White Spot Lesion"
      ],
      "interventions": [
        {
          "name": "Pro Seal Sealant",
          "type": "DEVICE"
        },
        {
          "name": "MI Varnish",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Texas A&M University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-10-01",
      "completion_date": "2020-03-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-23",
      "last_synced_at": "2026-09-26T18:04:29.827Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04560478"
    }
  ]
}