{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=pain+blocking&page=25",
    "query": {
      "intervention": "pain blocking",
      "page": 25
    },
    "page_size": 10
  },
  "pagination": {
    "page": 25,
    "page_size": 10,
    "total_count": 757,
    "total_pages": 76,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=pain+blocking&page=26&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=pain+blocking&page=24&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T09:58:46.924Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05261009",
      "title": "PENG Block Versus LP Block for THA Postop Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Hip Pain Chronic"
      ],
      "interventions": [
        {
          "name": "Peri-capsular Nerve Group (PENG)",
          "type": "DRUG"
        },
        {
          "name": "Lumbar Plexus Block (LPB)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 154,
      "start_date": "2022-06-13",
      "completion_date": "2023-07-20",
      "has_results": true,
      "last_update_posted_date": "2024-05-21",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05261009"
    },
    {
      "nct_id": "NCT04282239",
      "title": "Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "PECS2 block",
          "type": "PROCEDURE"
        },
        {
          "name": "Ropivacaine 0.5% Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Dexmedetomidine 0.004 MG/ML",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-03-01",
      "completion_date": "2022-07",
      "has_results": false,
      "last_update_posted_date": "2021-12-29",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Mineola, New York",
      "locations": [
        {
          "city": "Mineola",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04282239"
    },
    {
      "nct_id": "NCT02075411",
      "title": "Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Injury of Anterior Cruciate Ligament"
      ],
      "interventions": [
        {
          "name": "bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "continuous perineural infusion catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "14 Years to 18 Years"
      },
      "enrollment_count": 1,
      "start_date": "2014-03",
      "completion_date": "2015-02",
      "has_results": true,
      "last_update_posted_date": "2016-05-18",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02075411"
    },
    {
      "nct_id": "NCT07212114",
      "title": "Efficacy of EXPAREL vs. Bupivacaine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Total Ankle Arthroplasty",
        "Postsurgical Analgesia"
      ],
      "interventions": [
        {
          "name": "EXPAREL",
          "type": "DRUG"
        },
        {
          "name": "0.25% bupivacaine (HCl): 50 ml",
          "type": "DRUG"
        },
        {
          "name": "0.25% bupivacaine (HCl): 30 ml",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2025-11-17",
      "completion_date": "2029-08",
      "has_results": false,
      "last_update_posted_date": "2026-02-23",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07212114"
    },
    {
      "nct_id": "NCT03951649",
      "title": "Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Headache",
        "Pregnancy Related",
        "Occipital Nerve Block"
      ],
      "interventions": [
        {
          "name": "Occipital Nerve Block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 60 Years · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2020-02-10",
      "completion_date": "2022-12-31",
      "has_results": true,
      "last_update_posted_date": "2023-12-20",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03951649"
    },
    {
      "nct_id": "NCT05658874",
      "title": "A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Interstitial Cystitis",
        "Levator Spasm",
        "Bladder Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "Multimodal Bundle Drugs",
          "type": "DRUG"
        },
        {
          "name": "Operative Cystoscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Behavioral health consultation/therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pelvic floor physical therapy",
          "type": "OTHER"
        },
        {
          "name": "Usual Urogynecologic care",
          "type": "OTHER"
        },
        {
          "name": "Bladder Instillation",
          "type": "DRUG"
        },
        {
          "name": "Vaginal estrogen",
          "type": "DRUG"
        },
        {
          "name": "Methenamine",
          "type": "DRUG"
        },
        {
          "name": "Amitriptyline/Gabapentin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Jocelyn Fitzgerald",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 99 Years · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2022-12-06",
      "completion_date": "2025-12-30",
      "has_results": true,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05658874"
    },
    {
      "nct_id": "NCT02423876",
      "title": "Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intraoperative Complication",
        "Malignant Female Reproductive System Neoplasm",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Epidural analgesia",
          "type": "DRUG"
        },
        {
          "name": "Intraoperative Complication Management and Prevention",
          "type": "OTHER"
        },
        {
          "name": "Pain Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 104,
      "start_date": "2015-03-17",
      "completion_date": "2022-01-03",
      "has_results": true,
      "last_update_posted_date": "2023-09-06",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02423876"
    },
    {
      "nct_id": "NCT07588126",
      "title": "Ultrasound-guided Transgluteal Sciatic Nerve Hydrodissection for the Treatment of Sciatica in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sciatica Acute",
        "Sciatica Pain"
      ],
      "interventions": [
        {
          "name": "Ultrasound guided transgluteal sciatic nerve hydrodissection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 69,
      "start_date": "2024-01-12",
      "completion_date": "2025-02-21",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07588126"
    },
    {
      "nct_id": "NCT05110989",
      "title": "A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post Operative Pain"
      ],
      "interventions": [
        {
          "name": "AtriCure Cryo Nerve Block (cryoNB) Device Family",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "AtriCure, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 5000,
      "start_date": "2018-06-29",
      "completion_date": "2040-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 7,
      "location_summary": "Jacksonville, Florida • Orlando, Florida • Annapolis, Maryland + 4 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Annapolis",
          "state": "Maryland"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Manchester",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05110989"
    },
    {
      "nct_id": "NCT02341079",
      "title": "Intraoperative Liposomal Bupivacaine Injection in Primary Total Knee Arthroplasty",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis",
        "Osteoarthritis, Knee",
        "Arthritis, Degenerative",
        "Osteoarthrosis",
        "Osteoarthrosis Deformans"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Liposome Injection",
          "type": "DRUG"
        },
        {
          "name": "Indwelling femoral nerve block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2015-03",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2017-03-10",
      "last_synced_at": "2026-10-20T09:58:46.924Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02341079"
    }
  ]
}