{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=patient+global+impression+of+function",
    "query": {
      "intervention": "patient global impression of function"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T09:16:20.123Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07071350",
      "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Autonomic Nervous System Disease",
        "Concussive Injury",
        "Mild Traumatic Brain Injury",
        "Post Traumatic Stress Disorder",
        "Persistent Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "HRV Coherence Ratio",
          "type": "OTHER"
        },
        {
          "name": "NSI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pittsburgh Sleep Quality Index (PSQI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quantitative Sleep Measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Global Impression of Change (PGIC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Performance/NIH Toolbox Cognitive Battery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Interference/TBI-QoL Pain Interference Short-Form",
          "type": "OTHER"
        },
        {
          "name": "Patient Health Questionnaire-9 (PHQ-9)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTSD Checklist for DSM-5 (PCL-5)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HRV Biofeedback (HRV-B)",
          "type": "OTHER"
        },
        {
          "name": "Psychoeducational (Edu) Comparator Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2025-09-02",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07071350"
    },
    {
      "nct_id": "NCT03991429",
      "title": "Brain Imaging in Men With Lower Urinary Tract Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Voiding Disorders"
      ],
      "interventions": [
        {
          "name": "Simultaneous functional MRI and urodynamic studies",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Post Void Residual (PVR), Uroflow and Bladder Diary",
          "type": "OTHER"
        },
        {
          "name": "Urinalysis",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "The Methodist Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "90 Years",
        "sex": "MALE",
        "summary": "45 Years to 90 Years · Male only"
      },
      "enrollment_count": 11,
      "start_date": "2019-06-04",
      "completion_date": "2022-07-31",
      "has_results": false,
      "last_update_posted_date": "2023-01-05",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03991429"
    },
    {
      "nct_id": "NCT05419297",
      "title": "True Functional Restoration and Analgesia in Non-Radicular Low Back Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Back Pain Lower Back Chronic",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Buprenorphine Buccal Film [Belbuca]",
          "type": "DRUG"
        },
        {
          "name": "Urine Drug Screening",
          "type": "OTHER"
        },
        {
          "name": "actigraph",
          "type": "DEVICE"
        },
        {
          "name": "PROMIS 29",
          "type": "BEHAVIORAL"
        },
        {
          "name": "sit to stand test",
          "type": "OTHER"
        },
        {
          "name": "numerical rating scale pain score",
          "type": "OTHER"
        },
        {
          "name": "patient global impression of function",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PROMIS - sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Carolinas Pain Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-08-03",
      "completion_date": "2023-07",
      "has_results": false,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05419297"
    },
    {
      "nct_id": "NCT04064970",
      "title": "Patient Satisfaction Survey of Non-surgical Urinary Incontinence Treatment",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Urinary Incontinence"
      ],
      "interventions": [
        {
          "name": "patient acceptable symptom state (PASS)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 125,
      "start_date": "2019-03-14",
      "completion_date": "2020-07-01",
      "has_results": false,
      "last_update_posted_date": "2020-10-06",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04064970"
    },
    {
      "nct_id": "NCT05492500",
      "title": "A Study of Ponsegromab in People With Heart Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Main cohort (Cohort A): Ponsegromab low dose",
          "type": "DRUG"
        },
        {
          "name": "Main cohort (Cohort A): Ponsegromab medium dose",
          "type": "DRUG"
        },
        {
          "name": "Main cohort (Cohort A): ponsegromab high dose",
          "type": "DRUG"
        },
        {
          "name": "Main cohort (Cohort A): Matched placebo",
          "type": "OTHER"
        },
        {
          "name": "Open-label, PK Cohort (Cohort B): ponsegromab low dose",
          "type": "DRUG"
        },
        {
          "name": "Open-label, PK Cohort (Cohort B): ponsegromab medium dose",
          "type": "DRUG"
        },
        {
          "name": "Open-label, PK Cohort (Cohort B): ponsegromab high dose",
          "type": "DRUG"
        },
        {
          "name": "Optional Cohort C: Ponsegromab low dose",
          "type": "DRUG"
        },
        {
          "name": "Optional Cohort C: Matched placebo",
          "type": "OTHER"
        },
        {
          "name": "Optional Cohort D: Ponsegromab high dose",
          "type": "DRUG"
        },
        {
          "name": "Optional Cohort D: Matched placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 455,
      "start_date": "2022-09-26",
      "completion_date": "2025-03-05",
      "has_results": true,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 22,
      "location_summary": "Fairhope, Alabama • Los Angeles, California • Washington D.C., District of Columbia + 13 more",
      "locations": [
        {
          "city": "Fairhope",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Hazel Crest",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05492500"
    },
    {
      "nct_id": "NCT06840314",
      "title": "VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Genito-Pelvic Pain/Penetration Disorder",
        "Dyspareunia",
        "Vaginismus",
        "Pelvic Pain",
        "Vestibulodynia",
        "Vulvodynia (Chronic Vulvar Pain)"
      ],
      "interventions": [
        {
          "name": "Pelvic floor therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2025-03-01",
      "completion_date": "2026-03",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06840314"
    },
    {
      "nct_id": "NCT05214144",
      "title": "The In4M Study: Integrating 4 Methods to Assess Physical Function in Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Physical Function",
        "Cancer, Breast",
        "Lymphoma",
        "Patient Empowerment",
        "Patient Education",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "PRO Instruments assessment questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Baseline Survey Clinician- reported (ClinRO) ECOG",
          "type": "OTHER"
        },
        {
          "name": "Fitbit",
          "type": "DEVICE"
        },
        {
          "name": "Hugo Health (\"Hugo\")",
          "type": "OTHER"
        },
        {
          "name": "6 Minute Walk Test (6MWT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 208,
      "start_date": "2022-01-27",
      "completion_date": "2024-10-24",
      "has_results": false,
      "last_update_posted_date": "2024-11-07",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut • Rochester, Minnesota",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05214144"
    },
    {
      "nct_id": "NCT02420041",
      "title": "Comparing the Effects of Ultrasound Versus Fluoroscopy for Sacroiliac Joint Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sacroiliitis"
      ],
      "interventions": [
        {
          "name": "Active comparator: Fluoroscopic Guided SIJ injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Ultrasound Guided Sacroiliac Joint Injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Havel's Inc. EchoStim (facet tip) 21 Gauge 4\" needle",
          "type": "DEVICE"
        },
        {
          "name": "SonoSite S-nerve",
          "type": "DEVICE"
        },
        {
          "name": "iohexol",
          "type": "DEVICE"
        },
        {
          "name": "triamcinolone/lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2012-10",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2015-11-13",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02420041"
    },
    {
      "nct_id": "NCT00602290",
      "title": "Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Citalopram",
          "type": "DRUG"
        },
        {
          "name": "Methylphenidate (MPH)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 181,
      "start_date": "2008-02",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2018-01-11",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00602290"
    },
    {
      "nct_id": "NCT06433635",
      "title": "Sequential Multiple Assignment Randomized Trial for Bipolar Depression",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bipolar I Disorder",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Cariprazine",
          "type": "DRUG"
        },
        {
          "name": "Aripiprazole/Escitalopram combination",
          "type": "DRUG"
        },
        {
          "name": "Quetiapine",
          "type": "DRUG"
        },
        {
          "name": "Lurasidone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 2726,
      "start_date": "2024-10-01",
      "completion_date": "2030-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-12-16",
      "last_synced_at": "2026-09-03T09:16:20.123Z",
      "location_count": 17,
      "location_summary": "Birmingham, Alabama • Bloomington, Indiana • Baltimore, Maryland + 13 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Bloomington",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Belmont",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06433635"
    }
  ]
}