{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=physical+exercise+alone+%28PES%29+first",
    "query": {
      "intervention": "physical exercise alone (PES) first"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T18:49:50.868Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03069391",
      "title": "The Interactive Physical and Cognitive Exercise System",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease, Early Onset",
        "MCI",
        "Aging",
        "Mild Cognitive Impairment",
        "Neurocognitive Disorder",
        "Cognitive Impairment",
        "Cognitive Change"
      ],
      "interventions": [
        {
          "name": "physical exercise alone (PES) first",
          "type": "BEHAVIORAL"
        },
        {
          "name": "cognitive exercise alone (iCE) first",
          "type": "DEVICE"
        },
        {
          "name": "interactive Physical and Cognitive Exercise (iPACES™)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Union College, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2017-03-04",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-03-31",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "Schenectady, New York",
      "locations": [
        {
          "city": "Schenectady",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03069391"
    },
    {
      "nct_id": "NCT05639556",
      "title": "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "BMI and lean mass index from DXA",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Anthropometric Measurements",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hand-grip strength",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Six-minute walk Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sit-to-Stand Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Short physical performance battery (SPPB)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "BIA Sub-study",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Accelerometry to assess physical activity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Gastrointestinal (GI) and nutrition questionnaires:",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: PHQ-8",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: GAD-7",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ)",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: CF Fatalism Scale",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA)",
          "type": "OTHER"
        },
        {
          "name": "12-month Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Oral glucose tolerance testing (OGTT)",
          "type": "OTHER"
        },
        {
          "name": "Continuous glucose monitoring (CGM)",
          "type": "DEVICE"
        },
        {
          "name": "Chest CT scans (When available within the past 6 months in medical records)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hologic Dual X-Ray Absorptiometry (DXA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ultrasound Sub-study of assessment of appendage muscles using ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Hunger Vital Sign questionnaire",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory symptom questionnaire: CRISS",
          "type": "OTHER"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Additional Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "CF Management Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Food Frequency Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-20",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 23,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05639556"
    },
    {
      "nct_id": "NCT01988155",
      "title": "Eccentric Exercise Versus Eccentric Exercise and Astym for Insertional Achilles Tendinopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insertional Achilles Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Eccentric Exercise",
          "type": "OTHER"
        },
        {
          "name": "Astym",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Indiana University Health Ball Memorial Hospital Rehabiliation Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2013-12",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-02-23",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "Muncie, Indiana",
      "locations": [
        {
          "city": "Muncie",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01988155"
    },
    {
      "nct_id": "NCT05751785",
      "title": "Shockwave, Photobiomodulation, and Physical Therapy for Achilles Tendinopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Achilles Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        },
        {
          "name": "Shockwave Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Photobiomodulation Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Musculoskeletal Injury Rehabilitation Research for Operational Readiness",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 48,
      "start_date": "2023-02-13",
      "completion_date": "2024-11-14",
      "has_results": true,
      "last_update_posted_date": "2025-07-22",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "Tacoma, Washington",
      "locations": [
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05751785"
    },
    {
      "nct_id": "NCT03918681",
      "title": "Gait Retraining Enhances Athletes' Technique",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury",
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Therapeutic Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Keller Army Community Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-08-01",
      "completion_date": "2020-01-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "West Point, New York",
      "locations": [
        {
          "city": "West Point",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03918681"
    },
    {
      "nct_id": "NCT07397806",
      "title": "Home-Based Leg Dexterity Trainer for Management of Knee Osteoarthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteo Arthritis of the Knee"
      ],
      "interventions": [
        {
          "name": "Lex Dexterity Trainer",
          "type": "DEVICE"
        },
        {
          "name": "Wobble Board",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Steadman Philippon Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 82,
      "start_date": "2025-09-11",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "Vail, Colorado",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07397806"
    },
    {
      "nct_id": "NCT04162262",
      "title": "Effects of Exercise Versus Exercise and Instrument-Assisted Soft Tissue Mobilization for Plantar Fasciopathy Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plantar Fascitis"
      ],
      "interventions": [
        {
          "name": "Instrumental-assisted soft tissue mobilization (IASTM)",
          "type": "OTHER"
        },
        {
          "name": "High-Load Strength Training",
          "type": "OTHER"
        },
        {
          "name": "Plantar Flexor and Gastrocnemius Stretching",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas Tech University Health Sciences Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 83,
      "start_date": "2019-10-24",
      "completion_date": "2021-01-15",
      "has_results": false,
      "last_update_posted_date": "2021-02-05",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04162262"
    },
    {
      "nct_id": "NCT06692478",
      "title": "Benefits of Intrahospital Exercise Program in Pediatric HSCT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hematopoietic Stem Cell Transplant",
        "Pediatric Cancer",
        "Deconditioning"
      ],
      "interventions": [
        {
          "name": "Exercise regimen",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Phoenix Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "4 Years to 21 Years"
      },
      "enrollment_count": 40,
      "start_date": "2017-10-01",
      "completion_date": "2019-10-01",
      "has_results": false,
      "last_update_posted_date": "2024-11-18",
      "last_synced_at": "2026-09-24T18:49:50.868Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06692478"
    }
  ]
}