{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=prebiotic",
    "query": {
      "intervention": "prebiotic"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 166,
    "total_pages": 17,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=prebiotic&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T21:35:50.956Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00421941",
      "title": "Enteral Feeding Study of Formula Containing Fish Oil in Critical Care Setting",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trauma",
        "Tube Feeding"
      ],
      "interventions": [
        {
          "name": "Tube feeding",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Société des Produits Nestlé (SPN)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 50,
      "start_date": "2007-01",
      "completion_date": "2008-08",
      "has_results": false,
      "last_update_posted_date": "2013-11-01",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00421941"
    },
    {
      "nct_id": "NCT04491734",
      "title": "Tolerability Study of a Novel Microbiome Therapeutic in Subjects With Gastroesophageal Reflux Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "maltosyl-isomalto-oligosaccharides (MIMO)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "ISOThrive Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 156,
      "start_date": "2020-06-01",
      "completion_date": "2021-08-26",
      "has_results": false,
      "last_update_posted_date": "2021-08-30",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Manassas, Virginia",
      "locations": [
        {
          "city": "Manassas",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04491734"
    },
    {
      "nct_id": "NCT06548789",
      "title": "Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Melanoma"
      ],
      "interventions": [
        {
          "name": "Prebiotic Xnack Packouts",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2024-09-16",
      "completion_date": "2030-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06548789"
    },
    {
      "nct_id": "NCT06794619",
      "title": "Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Dietary Supplement with actives",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Olly, PBC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 34,
      "start_date": "2025-02-03",
      "completion_date": "2025-08",
      "has_results": false,
      "last_update_posted_date": "2025-07-15",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "St. Petersburg, Florida",
      "locations": [
        {
          "city": "St. Petersburg",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06794619"
    },
    {
      "nct_id": "NCT04629430",
      "title": "Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Myeloma",
        "Acute Myeloid Leukemia",
        "Acute Lymphoblastic Leukemia",
        "Non Hodgkin Lymphoma",
        "Acute Lymphocytic Leukemia",
        "Hodgkin Lymphoma",
        "Hodgkin Disease",
        "Myelofibrosis",
        "Myelodysplastic Syndromes",
        "Myeloproliferative Neoplasm",
        "Sickle Cell Disease",
        "Mantle Cell Lymphoma"
      ],
      "interventions": [
        {
          "name": "Pre-biotic foods/drinks",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2021-02-19",
      "completion_date": "2022-10-28",
      "has_results": false,
      "last_update_posted_date": "2023-01-04",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04629430"
    },
    {
      "nct_id": "NCT06544954",
      "title": "Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arterial Stiffness",
        "Blood Pressure",
        "Dysbiosis",
        "Inflammation",
        "Permeability; Increased"
      ],
      "interventions": [
        {
          "name": "Freeze-dried grape powder",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo powder",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "45 Years to 70 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-05-07",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06544954"
    },
    {
      "nct_id": "NCT05826184",
      "title": "Time Restricted Eating With or Without a Fiber Supplement for Weight Management in Pediatric Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight, Body"
      ],
      "interventions": [
        {
          "name": "Time restircted eating",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Time restricted eating + prebiotic",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 13,
      "start_date": "2023-11-17",
      "completion_date": "2025-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-03",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05826184"
    },
    {
      "nct_id": "NCT04060212",
      "title": "Mercury Metabolism by Bacteria in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mercury--Toxicology"
      ],
      "interventions": [
        {
          "name": "Tuna fish",
          "type": "OTHER"
        },
        {
          "name": "prebiotic",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 36,
      "start_date": "2019-10-01",
      "completion_date": "2023-08-31",
      "has_results": true,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04060212"
    },
    {
      "nct_id": "NCT03925597",
      "title": "Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prebiotics"
      ],
      "interventions": [
        {
          "name": "Fiber cycles ARM 1",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 2",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 3",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 4",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 5",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 7",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 8",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 9",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 10",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 11",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 12",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 13",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 14",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 15",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 16",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 17",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 18",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 19",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 20",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 21",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 22",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 23",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 24",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-01-21",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-26",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03925597"
    },
    {
      "nct_id": "NCT06464952",
      "title": "Microbiome Modulation With Prebiotics in PTSD and Cirrhosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cirrhosis",
        "PTSD"
      ],
      "interventions": [
        {
          "name": "Resistant potato starch",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Powdered cellulose",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Hunter Holmes Mcguire Veteran Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-07-31",
      "completion_date": "2027-09-25",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-09-03T21:35:50.956Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06464952"
    }
  ]
}