{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=prolonged+exposure",
    "query": {
      "intervention": "prolonged exposure"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 168,
    "total_pages": 17,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=prolonged+exposure&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T08:03:55.067Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03827057",
      "title": "RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Reconsolidation of Traumatic Memories (RTM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Prolonged Exposure (PE)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Uniformed Services University of the Health Sciences",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2019-06-12",
      "completion_date": "2025-05-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-15",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03827057"
    },
    {
      "nct_id": "NCT01459705",
      "title": "Comparing Virtual Reality Exposure Therapy to Prolonged Exposure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Disorders",
        "Post-Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Prolonged Exposure Therapy (PE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Virtual Reality Exposure Therapy (VRET)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Waitlist",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Center for Telehealth and Technology",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 162,
      "start_date": "2011-10",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Fort Bragg, North Carolina",
      "locations": [
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01459705"
    },
    {
      "nct_id": "NCT04609657",
      "title": "Liking Adaptation to Beverages With Varying Sweetness Levels After Prolonged Exposure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sweetness Liking Adaptation"
      ],
      "interventions": [
        {
          "name": "Flavored carbonated soft drink (CSD)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "PepsiCo Global R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "25 Years to 55 Years"
      },
      "enrollment_count": 168,
      "start_date": "2020-11-10",
      "completion_date": "2021-05-25",
      "has_results": false,
      "last_update_posted_date": "2022-03-24",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Addison, Illinois",
      "locations": [
        {
          "city": "Addison",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04609657"
    },
    {
      "nct_id": "NCT04280965",
      "title": "Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Post Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Quetiapine Fumarate",
          "type": "DRUG"
        },
        {
          "name": "Standard of care meducations",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2019-02-01",
      "completion_date": "2022-10-17",
      "has_results": false,
      "last_update_posted_date": "2023-05-09",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04280965"
    },
    {
      "nct_id": "NCT01102764",
      "title": "Prolonged Exposure (PE) for Post Traumatic Stress Disorder (PTSD): Telemedicine Versus In Person",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD"
      ],
      "interventions": [
        {
          "name": "Telemedicine",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In Person",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 150,
      "start_date": "2010-10",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2019-03-04",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01102764"
    },
    {
      "nct_id": "NCT01574118",
      "title": "Enhancing Exposure Therapy for Post-traumatic Stress Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Revisiting the Trauma memories",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Processing the trauma memories",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trauma Memory Retrieval Trial",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure to video clips related to the patient's trauma",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Breathing retraining",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure Homework",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Compound extinction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2012-04",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01574118"
    },
    {
      "nct_id": "NCT02290639",
      "title": "Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Brief Cognitive Behavioral Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Contact",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2012-12",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2016-01-12",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 2,
      "location_summary": "Lackland Air Force Base, Texas • Randolph Air Force Base, Texas",
      "locations": [
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Randolph Air Force Base",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02290639"
    },
    {
      "nct_id": "NCT02283333",
      "title": "Treatment of Prolonged Grief Disorder in Combat Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prolonged Grief Disorder"
      ],
      "interventions": [
        {
          "name": "BATE-G",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 155,
      "start_date": "2014-12-01",
      "completion_date": "2020-08-31",
      "has_results": true,
      "last_update_posted_date": "2021-02-18",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 2,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02283333"
    },
    {
      "nct_id": "NCT06968832",
      "title": "Project COMET: Massed Prolonged Exposure for PTSD and SUD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder (PTSD)",
        "Substance Use Disorders (SUD)",
        "Comorbidity",
        "Trauma and Stressor Related Disorders"
      ],
      "interventions": [
        {
          "name": "Massed Prolonged Exposure Therapy (M-PE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard outpatient SUD care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2025-09-02",
      "completion_date": "2029-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-27",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06968832"
    },
    {
      "nct_id": "NCT05663151",
      "title": "Mechanisms Underlying the Efficacy of Prolonged Exposure",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Prolonged Exposure Therapy for Posttraumatic Stress Disorder",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Boston Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-01-01",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-08",
      "last_synced_at": "2026-09-13T08:03:55.067Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05663151"
    }
  ]
}