{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=pupillometry&page=2", "query": { "intervention": "pupillometry", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=pupillometry&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-12T12:55:21.673Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04542707", "title": "Brainwave Activity Response on Common Physical Therapy Intervention", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain" ], "interventions": [ { "name": "joint manipulation", "type": "PROCEDURE" }, { "name": "Exercise", "type": "PROCEDURE" }, { "name": "Soft tissue massage", "type": "DEVICE" } ], "intervention_types": [ "PROCEDURE", "DEVICE" ], "sponsor": "Florida Gulf Coast University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 150, "start_date": "2020-08-20", "completion_date": "2025-07-01", "has_results": false, "last_update_posted_date": "2025-08-07", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Fort Myers, Florida", "locations": [ { "city": "Fort Myers", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04542707" }, { "nct_id": "NCT05584514", "title": "Effects of Listening Effort on Sentence Processing and Memory (Study 1)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sentence Stimulus", "Auditory Noise" ], "interventions": [ { "name": "Sentence Stimulus", "type": "OTHER" }, { "name": "Auditory Noise", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "60 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "60 Years to 90 Years" }, "enrollment_count": 80, "start_date": "2022-01-01", "completion_date": "2023-08-30", "has_results": false, "last_update_posted_date": "2023-11-18", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT05584514" }, { "nct_id": "NCT02058511", "title": "Infrared Pupillometry During General Anesthesia to Predict Pain", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pain", "Objective Assessment of Sedation" ], "interventions": [ { "name": "Anesthesia Premedication, Induction and Maintenance", "type": "DRUG" }, { "name": "Pupillometry after administration of anesthetic drugs", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 24, "start_date": "2012-11", "completion_date": "2016-11", "has_results": true, "last_update_posted_date": "2019-02-15", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02058511" }, { "nct_id": "NCT03862222", "title": "Atlas of Retinal Imaging in Alzheimer's Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer Disease", "Mild Cognitive Impairment", "Mild Dementia", "Aging", "Cognitive Change" ], "interventions": [ { "name": "Retinal Imaging", "type": "OTHER" }, { "name": "Pupillometry", "type": "OTHER" }, { "name": "Contrast Sensitivity", "type": "OTHER" }, { "name": "Neuropsychological Evaluation", "type": "DIAGNOSTIC_TEST" }, { "name": "APOE genotyping", "type": "GENETIC" }, { "name": "blood draw", "type": "OTHER" }, { "name": "Gait Assessment", "type": "OTHER" }, { "name": "Actigraphy", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DIAGNOSTIC_TEST", "GENETIC" ], "sponsor": "University of Rhode Island", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "55 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "55 Years to 80 Years" }, "enrollment_count": 165, "start_date": "2019-12-16", "completion_date": "2025-05-31", "has_results": false, "last_update_posted_date": "2025-06-05", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 4, "location_summary": "Clearwater, Florida • St. Petersburg, Florida • Kingston, Rhode Island + 1 more", "locations": [ { "city": "Clearwater", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" }, { "city": "Kingston", "state": "Rhode Island" }, { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT03862222" }, { "nct_id": "NCT01219569", "title": "Effects of Sevoflurane and Propofol on Light Flashed Evoked Pupillometry", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Blindness" ], "interventions": [ { "name": "propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 35, "start_date": "2007-08", "completion_date": "2010-01", "has_results": false, "last_update_posted_date": "2015-04-24", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Newark, New Jersey", "locations": [ { "city": "Newark", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT01219569" }, { "nct_id": "NCT04925622", "title": "Complex Eye Movements in Parkinson's Disease and Related Movement Disorders", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Parkinson Disease", "Parkinson's Disease and Parkinsonism", "Progressive Supranuclear Palsy", "Corticobasal Degeneration", "Parkinsonian Disorders", "Essential Tremor", "Vascular Parkinsonism", "Multiple System Atrophy, Parkinson Variant", "Parkinsonian Syndrome", "Huntington Disease" ], "interventions": [ { "name": "Complex eye movement exam", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Saccadous, Inc.", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 90, "start_date": "2021-01-04", "completion_date": "2022-04-15", "has_results": false, "last_update_posted_date": "2022-05-04", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT04925622" }, { "nct_id": "NCT06507748", "title": "A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Neurofibromatosis Type 1" ], "interventions": [ { "name": "AlgometRx Nociometer", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "120 Years", "sex": "ALL", "summary": "1 Year to 120 Years" }, "enrollment_count": 70, "start_date": "2026-02-18", "completion_date": "2027-05-01", "has_results": false, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 2, "location_summary": "Washington D.C., District of Columbia • Bethesda, Maryland", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06507748" }, { "nct_id": "NCT06949644", "title": "Pupillometry in Delayed Sleep Wake Phase Disorder", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Delayed Sleep-Wake Phase Disorder" ], "interventions": [ { "name": "Light and Citalopram", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 220, "start_date": "2025-09-01", "completion_date": "2029-08-31", "has_results": false, "last_update_posted_date": "2026-06-08", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06949644" }, { "nct_id": "NCT07236892", "title": "Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Movement Disorders", "Neurorehabilitation", "Non-invasive Activity Recording" ], "interventions": [ { "name": "Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2025-11-26", "completion_date": "2029-12-01", "has_results": false, "last_update_posted_date": "2025-12-24", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07236892" }, { "nct_id": "NCT05010473", "title": "Cortical Contributions to Frequency Following Responses and Modulation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Language" ], "interventions": [ { "name": "Speech and non-speech sound stimulation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "13 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "13 Years to 25 Years" }, "enrollment_count": 73, "start_date": "2022-01-20", "completion_date": "2026-03-04", "has_results": false, "last_update_posted_date": "2026-04-24", "last_synced_at": "2026-09-12T12:55:21.673Z", "location_count": 1, "location_summary": "Evanston, Illinois", "locations": [ { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05010473" } ] }