{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=quinolone", "query": { "intervention": "quinolone" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 627, "total_pages": 63, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=quinolone&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T04:47:52.949Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01988779", "title": "Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Rhinosinusitis" ], "interventions": [ { "name": "oral levofloxacin", "type": "DRUG" }, { "name": "nebulized levofloxacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2013-10", "completion_date": "2020-12-31", "has_results": true, "last_update_posted_date": "2021-03-24", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01988779" }, { "nct_id": "NCT00110461", "title": "Aripiprazole in Children and Adolescents With Bipolar I Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Aripiprazole", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 296, "start_date": "2005-03", "completion_date": "2007-02", "has_results": true, "last_update_posted_date": "2012-05-21", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 53, "location_summary": "Scottsdale, Arizona • Little Rock, Arkansas • National City, California + 50 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "National City", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00110461" }, { "nct_id": "NCT03347461", "title": "Otiprio Versus Ciprodex Tympanostomy Tube Outcomes", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Otorrhea", "Otitis Media With Effusion in Children" ], "interventions": [ { "name": "Otiprio", "type": "DRUG" }, { "name": "Ciprodex", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boston Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "10 Years", "sex": "ALL", "summary": "6 Months to 10 Years" }, "enrollment_count": 0, "start_date": "2018-10", "completion_date": "2019-06", "has_results": false, "last_update_posted_date": "2018-09-14", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03347461" }, { "nct_id": "NCT04639817", "title": "Trimethoprim-Sulfamethoxazole vs Levofloxacin as Targeted Therapy for Stenotrophomonas Maltophilia Infections: a Retrospective Cohort Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Stenotrophomonas Infection" ], "interventions": [ { "name": "Levofloxacin", "type": "DRUG" }, { "name": "trimethoprim-sulfamethoxazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institutes of Health Clinical Center (CC)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1621, "start_date": "2020-08-14", "completion_date": "2021-04-27", "has_results": false, "last_update_posted_date": "2021-04-28", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04639817" }, { "nct_id": "NCT02216071", "title": "Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis Externa", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Otitis Externa" ], "interventions": [ { "name": "Ciprodex®", "type": "DRUG" }, { "name": "EXL CDOS (Ciprofloxacin 0.3% and Dexamethasone 0.1%) Sterile Otic Suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Exela Pharma Sciences, LLC.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": null, "sex": "ALL", "summary": "6 Months and older" }, "enrollment_count": 499, "start_date": "2014-07-20", "completion_date": "2015-08-11", "has_results": true, "last_update_posted_date": "2021-05-28", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 46, "location_summary": "Birmingham, Alabama • Mesa, Arizona • Jonesboro, Arkansas + 36 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02216071" }, { "nct_id": "NCT02960763", "title": "Optimizing Outcomes of Treatment-Resistant Depression in Older Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Treatment Resistant Depression", "Major Depressive Disorder", "Treatment-Refractory Depression", "Late Life Depression", "Geriatric Depression" ], "interventions": [ { "name": "Aripiprazole Augmentation", "type": "DRUG" }, { "name": "Bupropion Augmentation", "type": "DRUG" }, { "name": "Switch to bupropion", "type": "DRUG" }, { "name": "Lithium Augmentation", "type": "DRUG" }, { "name": "Switch to nortriptyline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 742, "start_date": "2017-02-24", "completion_date": "2021-09-01", "has_results": true, "last_update_posted_date": "2024-10-03", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 4, "location_summary": "Los Angeles, California • St Louis, Missouri • New York, New York + 1 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "St Louis", "state": "Missouri" }, { "city": "New York", "state": "New York" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02960763" }, { "nct_id": "NCT02197130", "title": "Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Huntington's Disease" ], "interventions": [ { "name": "PF-02545920", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "30 Years to 65 Years" }, "enrollment_count": 272, "start_date": "2014-09", "completion_date": "2016-10", "has_results": true, "last_update_posted_date": "2017-11-17", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 22, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 12 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02197130" }, { "nct_id": "NCT00330863", "title": "Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder" ], "interventions": [ { "name": "Risperidone microspheres", "type": "DRUG" }, { "name": "Risperidone", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Ziprasidone", "type": "DRUG" }, { "name": "Aripiprazole", "type": "DRUG" }, { "name": "Paliperidone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 357, "start_date": "2006-05", "completion_date": "2011-01", "has_results": true, "last_update_posted_date": "2018-07-10", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 8, "location_summary": "Los Angeles, California • Augusta, Georgia • Iowa City, Iowa + 5 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Fall River", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00330863" }, { "nct_id": "NCT00789568", "title": "A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Phenylketonuria" ], "interventions": [ { "name": "sapropterin dihydrochloride", "type": "DRUG" }, { "name": "Moxifloxacin", "type": "DRUG" }, { "name": "Moxifloxacin placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioMarin Pharmaceutical", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 56, "start_date": "2008-10", "completion_date": "2009-10", "has_results": false, "last_update_posted_date": "2021-07-23", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 1, "location_summary": "Fargo, North Dakota", "locations": [ { "city": "Fargo", "state": "North Dakota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00789568" }, { "nct_id": "NCT05542264", "title": "A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Schizophrenia" ], "interventions": [ { "name": "SEP-363856", "type": "DRUG" }, { "name": "Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 19, "start_date": "2022-11-15", "completion_date": "2024-02-12", "has_results": false, "last_update_posted_date": "2024-06-26", "last_synced_at": "2026-09-03T04:47:52.949Z", "location_count": 4, "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • Dayton, Ohio + 1 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Dayton", "state": "Ohio" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05542264" } ] }