{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=sertraline+%28Zoloft%29", "query": { "intervention": "sertraline (Zoloft)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 216, "total_pages": 22, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=sertraline+%28Zoloft%29&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-24T21:45:18.686Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00262470", "title": "Treatment of Orthostatic Intolerance", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Tachycardia", "Chronic Orthostatic Intolerance" ], "interventions": [ { "name": "Acetazolamide", "type": "DRUG" }, { "name": "Atomoxetine", "type": "DRUG" }, { "name": "NO Drug", "type": "OTHER" }, { "name": "Clonidine", "type": "DRUG" }, { "name": "Entacapone", "type": "DRUG" }, { "name": "Entacapone & Propranolol", "type": "DRUG" }, { "name": "Atomoxetine & Propranolol", "type": "DRUG" }, { "name": "Indomethacin", "type": "DRUG" }, { "name": "Mecamylamine", "type": "DRUG" }, { "name": "Isosorbide Dinitrate", "type": "DRUG" }, { "name": "Melatonin", "type": "DIETARY_SUPPLEMENT" }, { "name": "Midodrine", "type": "DRUG" }, { "name": "Modafinil", "type": "DRUG" }, { "name": "Octreotide", "type": "DRUG" }, { "name": "Placebo", "type": "RADIATION" }, { "name": "Propranolol", "type": "DRUG" }, { "name": "Modafinil & Propranolol", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "IV Saline", "type": "PROCEDURE" }, { "name": "Drinking Water", "type": "OTHER" }, { "name": "Breathing Device", "type": "DEVICE" }, { "name": "memantine", "type": "DRUG" }, { "name": "Abdominal binder", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "RADIATION", "PROCEDURE", "DEVICE" ], "sponsor": "Satish R. Raj", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 150, "start_date": "1997-04", "completion_date": "2029-12", "has_results": false, "last_update_posted_date": "2025-10-08", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00262470" }, { "nct_id": "NCT02452983", "title": "Sertraline in Treatment of Low-Risk Myelodysplastic Syndrome", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Myelodysplastic Syndromes" ], "interventions": [ { "name": "Sertraline", "type": "DRUG" }, { "name": "Bone Marrow Aspirate/Biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Gustavo Rivero", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2015-05", "completion_date": "2020-11", "has_results": false, "last_update_posted_date": "2022-06-02", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 2, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02452983" }, { "nct_id": "NCT00118430", "title": "Stepped Care for Depression and Musculoskeletal Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain", "Depression" ], "interventions": [ { "name": "Stepped Care", "type": "BEHAVIORAL" }, { "name": "Antidepressants", "type": "DRUG" }, { "name": "Usual Care", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500, "start_date": "2004-09", "completion_date": "2008-08", "has_results": true, "last_update_posted_date": "2017-05-09", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00118430" }, { "nct_id": "NCT00169988", "title": "Antidepressant and Antipsychotic to Treat Attenuated Positive and Negative Symptoms", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prodromal Schizophrenia", "Psychotic Disorders" ], "interventions": [ { "name": "risperidone", "type": "DRUG" }, { "name": "sertraline-primary", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "22 Years", "sex": "ALL", "summary": "12 Years to 22 Years" }, "enrollment_count": 8, "start_date": "2004-03", "completion_date": "2007-04", "has_results": false, "last_update_posted_date": "2009-12-17", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "Glen Oaks, New York", "locations": [ { "city": "Glen Oaks", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00169988" }, { "nct_id": "NCT00080158", "title": "Treatment of Adolescent Suicide Attempters (TASA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Depression", "Suicide, Attempted" ], "interventions": [ { "name": "fluoxetine", "type": "DRUG" }, { "name": "sertraline", "type": "DRUG" }, { "name": "citalopram", "type": "DRUG" }, { "name": "escitalopram", "type": "DRUG" }, { "name": "bupropion", "type": "DRUG" }, { "name": "mirtazapine", "type": "DRUG" }, { "name": "venlafaxine", "type": "DRUG" }, { "name": "lithium", "type": "DRUG" }, { "name": "Cognitive Behavioral Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "12 Years to 18 Years" }, "enrollment_count": 120, "start_date": "2004-03", "completion_date": "2007-06", "has_results": false, "last_update_posted_date": "2020-06-22", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 6, "location_summary": "Baltimore, Maryland • New York, New York • Durham, North Carolina + 2 more", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00080158" }, { "nct_id": "NCT00382291", "title": "Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Obsessive-Compulsive Disorder" ], "interventions": [ { "name": "Regular Titration", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Slow Titration", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 56, "start_date": "2009-02", "completion_date": "2011-02", "has_results": true, "last_update_posted_date": "2013-03-12", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 2, "location_summary": "Gainesville, Florida • Tampa, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00382291" }, { "nct_id": "NCT07139834", "title": "Pattern Separation in Major Depressive Disorder", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Major Depressive Disorder (MDD)" ], "interventions": [ { "name": "SSRI (escitalopram or sertraline)", "type": "DRUG" }, { "name": "Extended-Release Memantine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jeffrey Miller", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 30, "start_date": "2026-06-01", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07139834" }, { "nct_id": "NCT00050804", "title": "Evaluation of Stress Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Acute Traumatic Stress Disorders", "Post-Traumatic Stress Disorders" ], "interventions": [ { "name": "sertraline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 80, "start_date": "2002-12", "completion_date": "2004-02", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00050804" }, { "nct_id": "NCT00834652", "title": "Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Sertraline", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "20 Years to 60 Years" }, "enrollment_count": 206, "start_date": "2007-09", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2018-09-10", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00834652" }, { "nct_id": "NCT06591091", "title": "Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life Depression", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Clemastine Fumarate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Illinois at Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 80, "start_date": "2025-12-10", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-06-30", "last_synced_at": "2026-09-24T21:45:18.686Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06591091" } ] }