{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=sertraline-primary", "query": { "intervention": "sertraline-primary" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=sertraline-primary&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-11T17:02:09.476Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01028625", "title": "Depression and Self-care in Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure", "Depression" ], "interventions": [ { "name": "Cognitive Behavior Therapy", "type": "BEHAVIORAL" }, { "name": "Heart Failure Self-care Education", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 158, "start_date": "2010-01", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2014-05-29", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01028625" }, { "nct_id": "NCT00058903", "title": "Treatment of Cholestatic Pruritus With Sertraline", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pruritus", "Liver Cirrhosis, Biliary", "Hepatitis C" ], "interventions": [ { "name": "sertraline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "21 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2003-04", "completion_date": "2005-03", "has_results": false, "last_update_posted_date": "2010-01-13", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00058903" }, { "nct_id": "NCT00198094", "title": "A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Panic Disorder" ], "interventions": [ { "name": "Sertraline and Alprazolam XR", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 150, "start_date": "2003-12", "completion_date": "2007-09", "has_results": false, "last_update_posted_date": "2007-10-22", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 3, "location_summary": "Tampa, Florida • Indianapolis, Indiana • Philadelphia, Pennsylvania", "locations": [ { "city": "Tampa", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00198094" }, { "nct_id": "NCT07139834", "title": "Pattern Separation in Major Depressive Disorder", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Major Depressive Disorder (MDD)" ], "interventions": [ { "name": "SSRI (escitalopram or sertraline)", "type": "DRUG" }, { "name": "Extended-Release Memantine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jeffrey Miller", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 30, "start_date": "2026-06-01", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07139834" }, { "nct_id": "NCT03511118", "title": "Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lactating Women on Select DOI", "Breastfed Infants of Mothers on Select DOI" ], "interventions": [ { "name": "Tranexamic acid (TXA)", "type": "DRUG" }, { "name": "labetalol", "type": "DRUG" }, { "name": "metformin", "type": "DRUG" }, { "name": "nifedipine", "type": "DRUG" }, { "name": "clindamycin", "type": "DRUG" }, { "name": "oxycodone", "type": "DRUG" }, { "name": "azithromycin", "type": "DRUG" }, { "name": "escitalopram", "type": "DRUG" }, { "name": "sertraline", "type": "DRUG" }, { "name": "ondansetron", "type": "DRUG" }, { "name": "Ciprofloxacin", "type": "DRUG" }, { "name": "Doxycycline", "type": "DRUG" }, { "name": "Levofloxacin", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" }, { "name": "Sumatriptan", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Cyclobenzaprine", "type": "DRUG" }, { "name": "Furosemide", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Hydroxyurea", "type": "DRUG" }, { "name": "Rosuvastatin", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Trazodone", "type": "DRUG" }, { "name": "Valganciclovir", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Verapamil", "type": "DRUG" }, { "name": "Remdesivir", "type": "DRUG" }, { "name": "Anakinra", "type": "DRUG" }, { "name": "Tocilizumab", "type": "DRUG" }, { "name": "Fluvoxamine", "type": "DRUG" }, { "name": "Amoxicillin", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Hydrocodone", "type": "DRUG" }, { "name": "Levetiracetam", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Buprenorphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1600, "start_date": "2018-10-04", "completion_date": "2028-07-31", "has_results": false, "last_update_posted_date": "2026-07-29", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 20, "location_summary": "La Jolla, California • Loma Linda, California • Chicago, Illinois + 15 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03511118" }, { "nct_id": "NCT00074815", "title": "Treatment of Obsessive Compulsive Disorder in Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Obsessive-Compulsive Disorder" ], "interventions": [ { "name": "Serotonin reuptake inhibitors management", "type": "DRUG" }, { "name": "Cognitive behavioral therapy by a psychologist", "type": "BEHAVIORAL" }, { "name": "Instructional cognitive behavioral therapy by a psychiatrist", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 124, "start_date": "2003-09", "completion_date": "2009-11", "has_results": true, "last_update_posted_date": "2014-07-29", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 3, "location_summary": "Durham, North Carolina • Philadelphia, Pennsylvania • Providence, Rhode Island", "locations": [ { "city": "Durham", "state": "North Carolina" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT00074815" }, { "nct_id": "NCT02458690", "title": "eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression", "Major Depressive Disorder", "Dysthymic Disorder", "Depressive Symptoms", "Cardiovascular Diseases", "Heart Diseases", "Coronary Artery Disease", "Stroke" ], "interventions": [ { "name": "Beating the Blues (BtB)", "type": "BEHAVIORAL" }, { "name": "Problem Solving Treatment in Primary Care (PST-PC)", "type": "BEHAVIORAL" }, { "name": "Antidepressant Medications", "type": "DRUG" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "DRUG", "OTHER" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 216, "start_date": "2015-07", "completion_date": "2021-03", "has_results": true, "last_update_posted_date": "2023-10-19", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02458690" }, { "nct_id": "NCT01993017", "title": "Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Coronary Syndrome", "Depressive Symptoms" ], "interventions": [ { "name": "Cognitive Behavioral Therapy (CBT)", "type": "OTHER" }, { "name": "Antidepressant Medication", "type": "DRUG" }, { "name": "Standard Care", "type": "OTHER" }, { "name": "Depressive symptom screener", "type": "OTHER" }, { "name": "No intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 1501, "start_date": "2013-11", "completion_date": "2019-07-31", "has_results": true, "last_update_posted_date": "2023-04-14", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 4, "location_summary": "Bloomington, Minnesota • New York, New York • Henderson, North Carolina + 1 more", "locations": [ { "city": "Bloomington", "state": "Minnesota" }, { "city": "New York", "state": "New York" }, { "city": "Henderson", "state": "North Carolina" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01993017" }, { "nct_id": "NCT01347541", "title": "Piloting Acute Care to Primary Care Linkage of Safety Net Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Posttraumatic Stress Disorder" ], "interventions": [ { "name": "Cognitive Behavioral Therapy", "type": "BEHAVIORAL" }, { "name": "Motivational Interviewing", "type": "BEHAVIORAL" }, { "name": "FDA-Approved Anti-Anxiety Medications", "type": "DRUG" }, { "name": "Standard Care Control", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4, "start_date": "2011-01", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2021-03-10", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01347541" }, { "nct_id": "NCT03222570", "title": "An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depressive Disorder" ], "interventions": [ { "name": "Interpersonal Psychotherapy for Depressed Adolescents", "type": "BEHAVIORAL" }, { "name": "Selective Serotonin Reuptake Inhibitor", "type": "DRUG" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "DRUG", "OTHER" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "12 Years to 18 Years" }, "enrollment_count": 90, "start_date": "2018-02-26", "completion_date": "2024-04-28", "has_results": true, "last_update_posted_date": "2025-07-02", "last_synced_at": "2026-09-11T17:02:09.476Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03222570" } ] }