{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=sham+ITD",
    "query": {
      "intervention": "sham ITD"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T14:14:32.192Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00576524",
      "title": "Application of Impedance Threshold Device Technologies to Treat and Prevent Hypotension During Dialysis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Intradialytic Hypotension",
        "End Stage Renal Disease",
        "Low Blood Pressure"
      ],
      "interventions": [
        {
          "name": "ITD",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 2,
      "start_date": "2008-09",
      "completion_date": "2011-02",
      "has_results": true,
      "last_update_posted_date": "2013-02-26",
      "last_synced_at": "2026-09-06T14:14:32.192Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00576524"
    },
    {
      "nct_id": "NCT00256724",
      "title": "Efficacy Study of a Facemask Device to Treat Hypotension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypotension"
      ],
      "interventions": [
        {
          "name": "Impedance Threshold Device",
          "type": "DEVICE"
        },
        {
          "name": "sham ITD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Advanced Circulatory Systems",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 47,
      "start_date": "2005-06",
      "completion_date": "2008-01",
      "has_results": true,
      "last_update_posted_date": "2013-07-31",
      "last_synced_at": "2026-09-06T14:14:32.192Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00256724"
    },
    {
      "nct_id": "NCT00394706",
      "title": "Resuscitation Outcomes Consortium (ROC) Prehospital Resuscitation Using an Impedance Valve",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Heart Arrest"
      ],
      "interventions": [
        {
          "name": "Impedance Threshold Device (ITD)",
          "type": "DEVICE"
        },
        {
          "name": "Sham ITD",
          "type": "DEVICE"
        },
        {
          "name": "Analyze early",
          "type": "OTHER"
        },
        {
          "name": "Analyze later",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11738,
      "start_date": "2007-06",
      "completion_date": "2010-07",
      "has_results": true,
      "last_update_posted_date": "2018-08-09",
      "last_synced_at": "2026-09-06T14:14:32.192Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • San Diego, California • Portland, Oregon + 4 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00394706"
    },
    {
      "nct_id": "NCT00962728",
      "title": "Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postural Tachycardia Syndrome",
        "Postural Orthostatic Tachycardia Syndrome"
      ],
      "interventions": [
        {
          "name": "Inspiratory Threshold Device (Res-Q-Gard ITD)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Inspiratory Threshold Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alfredo Gamboa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2009-07",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-09-06T14:14:32.192Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00962728"
    },
    {
      "nct_id": "NCT00962884",
      "title": "Breathing Device for Orthostatic Hypotension (OH)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthostatic Hypotension"
      ],
      "interventions": [
        {
          "name": "Inspiratory Threshold Device (Res-Q-Gard ITD)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Inspiratory Threshold Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alfredo Gamboa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2010-12",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2021-11-22",
      "last_synced_at": "2026-09-06T14:14:32.192Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00962884"
    }
  ]
}