{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=spinal+manipulative+therapy&page=2",
    "query": {
      "intervention": "spinal manipulative therapy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=spinal+manipulative+therapy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T16:24:06.239Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03916705",
      "title": "Thoraco-Lumbar Fascia Mobility",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "High Velocity Low amplitude spinal manipulation (HVLA-SM)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 31,
      "start_date": "2019-09-09",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-05-04",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03916705"
    },
    {
      "nct_id": "NCT06965920",
      "title": "Influence of Flexion Distraction Manipulation on Measures of Performance and Postural Control",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spine Condition",
        "Low Back Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Keiser University College of Chiropractic Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-05-15",
      "completion_date": "2026-05-14",
      "has_results": false,
      "last_update_posted_date": "2025-05-18",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "West Palm Beach, Florida",
      "locations": [
        {
          "city": "West Palm Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06965920"
    },
    {
      "nct_id": "NCT03749564",
      "title": "Influence of Opioid Use on the Effects of Spinal Manipulative Therapy for Low Back Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "SMT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Activation Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mobilizing Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Extended SMT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 7,
      "start_date": "2019-01-17",
      "completion_date": "2020-03-03",
      "has_results": false,
      "last_update_posted_date": "2022-09-22",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03749564"
    },
    {
      "nct_id": "NCT01312233",
      "title": "Collaborative Care for Older Adults With Back Pain (COCOA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Medical Care",
          "type": "OTHER"
        },
        {
          "name": "Dual Care",
          "type": "OTHER"
        },
        {
          "name": "Shared Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 131,
      "start_date": "2011-03",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2021-03-30",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 2,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        },
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01312233"
    },
    {
      "nct_id": "NCT00163124",
      "title": "A Randomized Controlled Trial of Best Approach to Care Compared to Diversified Chiropractic Adjustive Technique",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Headache",
        "Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "spinal manipulation & patient education/nutrition",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Parker College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 155,
      "start_date": "2005-03",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2005-09-13",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00163124"
    },
    {
      "nct_id": "NCT00475787",
      "title": "Chiropractic Management of Chronic Lower Back Pain in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Detuned Ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2008-04",
      "completion_date": "2011-04",
      "has_results": true,
      "last_update_posted_date": "2014-12-30",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 2,
      "location_summary": "Buffalo, New York • Canandaigua, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Canandaigua",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475787"
    },
    {
      "nct_id": "NCT04513535",
      "title": "Effects of Manual Therapy on Shoulder Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Manipulations",
        "Shoulder",
        "Range of Motion",
        "Muscle Strength",
        "Surface Electromyography"
      ],
      "interventions": [
        {
          "name": "Thoracic Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Cervical Manipulation",
          "type": "OTHER"
        },
        {
          "name": "glenohumeral posterior glide mobilization",
          "type": "OTHER"
        },
        {
          "name": "Sleeper stretch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Hartford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 48,
      "start_date": "2020-02-07",
      "completion_date": "2020-11-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-23",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "West Hartford, Connecticut",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04513535"
    },
    {
      "nct_id": "NCT01940744",
      "title": "Prescriptive Mobilization Versus a Pragmatic Mobilization",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mechanical Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Prescriptive Mobilization",
          "type": "PROCEDURE"
        },
        {
          "name": "Pragmatic Mobilization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Walsh University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2013-10",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2013-11-13",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 3,
      "location_summary": "Des Moines, Iowa • North Canton, Ohio • Youngstown, Ohio",
      "locations": [
        {
          "city": "Des Moines",
          "state": "Iowa"
        },
        {
          "city": "North Canton",
          "state": "Ohio"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01940744"
    },
    {
      "nct_id": "NCT01168999",
      "title": "The Mechanisms of Manual Therapy in the Treatment of Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "spinal manipulation",
          "type": "OTHER"
        },
        {
          "name": "sham spinal manipulation",
          "type": "OTHER"
        },
        {
          "name": "Enhanced sham spinal manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 110,
      "start_date": "2009-09",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2015-10-28",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01168999"
    },
    {
      "nct_id": "NCT05726331",
      "title": "Chronic Non-Specific Neck Pain Treated With Tai Chi and Chiropractic Care",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Chiropractic Care",
          "type": "OTHER"
        },
        {
          "name": "Tai Chi",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Harvard University Faculty of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2023-10-25",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-01-19",
      "last_synced_at": "2026-09-28T16:24:06.239Z",
      "location_count": 1,
      "location_summary": "Chestnut Hill, Massachusetts",
      "locations": [
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05726331"
    }
  ]
}