{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=spine+manipulations",
    "query": {
      "intervention": "spine manipulations"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 68,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=spine+manipulations&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T17:40:45.007Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03616145",
      "title": "Effects of Osteopathic Manipulative Treatment (OMT) on Gait Biomechanics in Parkinson's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment (OMT)",
          "type": "PROCEDURE"
        },
        {
          "name": "Light Touch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2018-07-01",
      "completion_date": "2024-01-21",
      "has_results": false,
      "last_update_posted_date": "2023-11-13",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03616145"
    },
    {
      "nct_id": "NCT06906107",
      "title": "Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain Musculoskeletal",
        "Neck Pain Treatment",
        "Cervicalgia"
      ],
      "interventions": [
        {
          "name": "Cervical Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Exercise",
          "type": "PROCEDURE"
        },
        {
          "name": "Mobilization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Baylor University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 160,
      "start_date": "2025-06-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 4,
      "location_summary": "Rochester, Minnesota • Syracuse, New York • Waco, Texas + 1 more",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Waco",
          "state": "Texas"
        },
        {
          "city": "Green Bay",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06906107"
    },
    {
      "nct_id": "NCT02111278",
      "title": "Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Lumbar Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Sham Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 35,
      "start_date": "2012-05",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2014-12-23",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 3,
      "location_summary": "Columbus, Ohio • Westerville, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Westerville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02111278"
    },
    {
      "nct_id": "NCT02750566",
      "title": "Comparing the Effect of Osteopathic Manipulative Medicine (OMM) Versus Counseling in the Treatment of Concussion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Concussion Symptoms",
        "Distorted; Balance"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Counseling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 33,
      "start_date": "2015-11-15",
      "completion_date": "2023-10-04",
      "has_results": false,
      "last_update_posted_date": "2024-08-07",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02750566"
    },
    {
      "nct_id": "NCT05926674",
      "title": "Does Manual Therapy Provide Immediate Improvement in Lumbar Range of Motion?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "N/A Healthy Individuals"
      ],
      "interventions": [
        {
          "name": "Myofascial Release",
          "type": "OTHER"
        },
        {
          "name": "Light Touch Contact",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2023-07-15",
      "completion_date": "2023-07-26",
      "has_results": false,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05926674"
    },
    {
      "nct_id": "NCT04976985",
      "title": "Osteopathic Manipulative Treatment and Migraine Headaches",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Migraine",
        "Migraine Disorders",
        "Headache Disorders",
        "Headache, Migraine"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Therapy (OMT)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "St. Luke's Hospital, Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 140,
      "start_date": "2018-10-02",
      "completion_date": "2022-03-30",
      "has_results": false,
      "last_update_posted_date": "2021-08-03",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04976985"
    },
    {
      "nct_id": "NCT00703248",
      "title": "The Human Immunodeficiency Virus and Osteopathic Manipulation Evaluation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatments",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "MALE",
        "summary": "18 Years to 65 Years · Male only"
      },
      "enrollment_count": null,
      "start_date": "2007-10",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2008-07-08",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 1,
      "location_summary": "Fort Lauderdale, Florida",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00703248"
    },
    {
      "nct_id": "NCT01530321",
      "title": "Cervicogenic Headache Dose-Response",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cervicogenic Headache"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Light Massage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Western States",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 256,
      "start_date": "2012-08",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2018-11-20",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 2,
      "location_summary": "Bloomington, Minnesota • Portland, Oregon",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01530321"
    },
    {
      "nct_id": "NCT01318720",
      "title": "Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Manual Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Masefield and Cavallaro Physical Therapy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 64,
      "start_date": "2009-11",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 2,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01318720"
    },
    {
      "nct_id": "NCT01689168",
      "title": "Chiropractic Treatment With Counseling Versus Counseling Alone for Promoting Smoking Cessation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Chiropractic adjustment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "Southern California University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2012-03",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2015-05-20",
      "last_synced_at": "2026-09-13T17:40:45.007Z",
      "location_count": 1,
      "location_summary": "Whittier, California",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01689168"
    }
  ]
}