{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=suprachoroidal+sham", "query": { "intervention": "suprachoroidal sham" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 8, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-09T14:31:29.752Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03126786", "title": "Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetic Macular Edema" ], "interventions": [ { "name": "IVT aflibercept", "type": "DRUG" }, { "name": "Sham SC", "type": "DRUG" }, { "name": "SC CLS-TA", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clearside Biomedical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 71, "start_date": "2017-07-11", "completion_date": "2018-04-17", "has_results": true, "last_update_posted_date": "2021-05-13", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 29, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Bakersfield, California + 25 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Mountain View", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03126786" }, { "nct_id": "NCT02595398", "title": "Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Uveitis", "Uveitis, Posterior", "Uveitis, Anterior", "Uveitis, Intermediate", "Panuveitis" ], "interventions": [ { "name": "4mg CLS-TA Suprachoriodal Injection", "type": "DRUG" }, { "name": "Sham Procedure", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clearside Biomedical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 160, "start_date": "2015-11-17", "completion_date": "2018-01-18", "has_results": true, "last_update_posted_date": "2021-05-28", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 40, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Bakersfield, California + 36 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02595398" }, { "nct_id": "NCT03203447", "title": "Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Macular Edema", "Retinal Vein Occlusion" ], "interventions": [ { "name": "suprachoroidal CLS-TA", "type": "DRUG" }, { "name": "suprachoroidal sham", "type": "DRUG" }, { "name": "Lucentis or Avastin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clearside Biomedical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 325, "start_date": "2018-03-05", "completion_date": "2018-12-18", "has_results": true, "last_update_posted_date": "2021-04-23", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 72, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Arcadia, California + 61 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Arcadia", "state": "California" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03203447" }, { "nct_id": "NCT06007690", "title": "A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Choroidal Melanoma", "Indeterminate Lesions", "Uveal Melanoma", "Ocular Melanoma" ], "interventions": [ { "name": "Bel-sar", "type": "DRUG" }, { "name": "Suprachoroidal Microinjector", "type": "DEVICE" }, { "name": "Infrared Laser", "type": "DEVICE" }, { "name": "Sham Infrared Laser", "type": "DEVICE" }, { "name": "Sham Microinjector", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Aura Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2023-12-06", "completion_date": "2028-08-15", "has_results": false, "last_update_posted_date": "2026-07-31", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 32, "location_summary": "La Jolla, California • Los Angeles, California • Palo Alto, California + 27 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06007690" }, { "nct_id": "NCT02303184", "title": "Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Macular Edema", "Retinal Vein Occlusion" ], "interventions": [ { "name": "4 mg CLS-TA", "type": "DRUG" }, { "name": "Sham", "type": "DRUG" }, { "name": "IVT aflibercept", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clearside Biomedical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2015-01", "completion_date": "2016-03", "has_results": true, "last_update_posted_date": "2021-02-08", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 14, "location_summary": "Phoenix, Arizona • Beverly Hills, California • San Diego, California + 11 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Boynton Beach", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02303184" }, { "nct_id": "NCT02952001", "title": "MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Uveitis", "Uveitis, Posterior", "Uveitis, Anterior", "Uveitis, Intermediate", "Panuveitis" ], "interventions": [ { "name": "4 mg CLS-TA Suprachoriodal Injection", "type": "DRUG" }, { "name": "Sham procedure", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clearside Biomedical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2017-12-13", "completion_date": "2018-05-22", "has_results": true, "last_update_posted_date": "2021-06-02", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 10, "location_summary": "Phoenix, Arizona • Mountain View, California • Fort Lauderdale, Florida + 7 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Mountain View", "state": "California" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Marietta", "state": "Georgia" }, { "city": "Ayer", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02952001" }, { "nct_id": "NCT07592273", "title": "Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Diabetic Retinopathy" ], "interventions": [ { "name": "Surabgene Lomparvovec", "type": "DRUG" }, { "name": "Sham", "type": "DRUG" }, { "name": "Topical Steroid", "type": "DRUG" }, { "name": "Artificial Tears", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 576, "start_date": "2026-06-01", "completion_date": "2036-01", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 29, "location_summary": "Phoenix, Arizona • Scottsdale, Arizona • Bakersfield, California + 26 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Mountain View", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07592273" }, { "nct_id": "NCT02980874", "title": "Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Macular Edema", "Retinal Vein Occlusion" ], "interventions": [ { "name": "suprachoroidal CLS-TA", "type": "DRUG" }, { "name": "suprachoroidal sham", "type": "DRUG" }, { "name": "IVT aflibercept", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clearside Biomedical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 460, "start_date": "2017-01-31", "completion_date": "2018-12-10", "has_results": true, "last_update_posted_date": "2021-04-14", "last_synced_at": "2026-09-09T14:31:29.752Z", "location_count": 58, "location_summary": "Peoria, Arizona • Phoenix, Arizona • Tucson, Arizona + 51 more", "locations": [ { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02980874" } ] }