{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=tetanus%2C+diphtheria+and+acellular+pertussis+vaccine+%28Tdap%29&page=2",
    "query": {
      "intervention": "tetanus, diphtheria and acellular pertussis vaccine (Tdap)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 44,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=tetanus%2C+diphtheria+and+acellular+pertussis+vaccine+%28Tdap%29&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=tetanus%2C+diphtheria+and+acellular+pertussis+vaccine+%28Tdap%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-11T07:35:52.539Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03165981",
      "title": "Fever After Simultaneous Versus Sequential Vaccination in Young Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fever After Vaccination",
        "Fever",
        "Febrile Seizure"
      ],
      "interventions": [
        {
          "name": "PCV13",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DTaP",
          "type": "BIOLOGICAL"
        },
        {
          "name": "IIV",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "16 Months",
        "sex": "ALL",
        "summary": "12 Months to 16 Months"
      },
      "enrollment_count": 221,
      "start_date": "2017-08-25",
      "completion_date": "2018-01-15",
      "has_results": true,
      "last_update_posted_date": "2024-11-18",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 3,
      "location_summary": "Oakland, California • Atlanta, Georgia • Durham, North Carolina",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03165981"
    },
    {
      "nct_id": "NCT00662870",
      "title": "Study of the Safety, Immunogenicity and Lot Comparability of DAPTACEL When Administered With Other Recommended Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diphtheria",
        "Tetanus",
        "Whooping Cough",
        "Polio",
        "Haemophilus Influenzae Type b"
      ],
      "interventions": [
        {
          "name": "DAPTACEL® (Diphtheria and Tetanus Toxoids and Acellular Pertussis vaccine)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pentacel: DTaP-IPV/Hib",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Days",
        "maximum_age": "84 Days",
        "sex": "ALL",
        "summary": "42 Days to 84 Days"
      },
      "enrollment_count": 1941,
      "start_date": "2001-05",
      "completion_date": "2004-01",
      "has_results": false,
      "last_update_posted_date": "2012-01-31",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 26,
      "location_summary": "Fayetteville, AR 72703, Arkansas • Jonesboro, AR 72401, Arkansas • Little Rock, AR 72211, Arkansas + 23 more",
      "locations": [
        {
          "city": "Fayetteville, AR 72703",
          "state": "Arkansas"
        },
        {
          "city": "Jonesboro, AR 72401",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock, AR 72211",
          "state": "Arkansas"
        },
        {
          "city": "Fountain Valley, CA 92708",
          "state": "California"
        },
        {
          "city": "Englewood, CO 80112",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00662870"
    },
    {
      "nct_id": "NCT00255047",
      "title": "Safety and Immune Response of Different Pediatric Combination Vaccines.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diphtheria",
        "Polio",
        "Pertussis"
      ],
      "interventions": [
        {
          "name": "DAPTACEL®. (DTaP), IPOL®., and ActHIB®.",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pentacel®: DTaP-IPV/Hib combined",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DTaP-IPV and ActHIB®",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Days",
        "maximum_age": "89 Days",
        "sex": "ALL",
        "summary": "42 Days to 89 Days"
      },
      "enrollment_count": 2167,
      "start_date": "2005-11",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2014-02-14",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 36,
      "location_summary": "Tuscaloosa, Alabama • Fayetteville, Arkansas • Jonesboro, Arkansas + 29 more",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00255047"
    },
    {
      "nct_id": "NCT05183516",
      "title": "Tdap and Biomarkers of Alzheimer's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease, Late Onset"
      ],
      "interventions": [
        {
          "name": "tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Mindful Diagnostics and Therapeutics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2023-05-01",
      "completion_date": "2024-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-08-25",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 1,
      "location_summary": "Eau Claire, Wisconsin",
      "locations": [
        {
          "city": "Eau Claire",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05183516"
    },
    {
      "nct_id": "NCT05028634",
      "title": "Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "Tetanus, diphtheria, and acellular pertussis vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal polysaccharide vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Seasonal influenza vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Celgene",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 63,
      "start_date": "2021-11-11",
      "completion_date": "2023-11-15",
      "has_results": true,
      "last_update_posted_date": "2025-02-11",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 29,
      "location_summary": "Palo Alto, California • Colorado Springs, Colorado • Southington, Connecticut + 26 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Southington",
          "state": "Connecticut"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Port Charlotte",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05028634"
    },
    {
      "nct_id": "NCT00346073",
      "title": "Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acellular Pertussis",
        "Diphtheria",
        "Tetanus"
      ],
      "interventions": [
        {
          "name": "Boostrix™",
          "type": "BIOLOGICAL"
        },
        {
          "name": "ADACEL®",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "19 Years to 64 Years"
      },
      "enrollment_count": 2337,
      "start_date": "2006-07-13",
      "completion_date": "2007-03-07",
      "has_results": true,
      "last_update_posted_date": "2018-08-07",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 42,
      "location_summary": "Huntsville, Alabama • Chandler, Arizona • Mesa, Arizona + 36 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Peoria",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00346073"
    },
    {
      "nct_id": "NCT00457249",
      "title": "A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pertussis",
        "Tetanus",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "ADACEL®: Tetanus, Reduced Diphtheria and Acellular Pertussis Adsorbed",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DECAVAC®: Tetanus and Diphtheria Toxoids Adsorbed",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1564,
      "start_date": "2007-03",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2012-10-19",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 19,
      "location_summary": "Chandler, Arizona • Phoenix, Arizona • Cypress, California + 15 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Cypress",
          "state": "California"
        },
        {
          "city": "San Luis Obispo",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00457249"
    },
    {
      "nct_id": "NCT00707148",
      "title": "Pertussis Vaccine in Healthy Pregnant Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diphtheria",
        "Pertussis",
        "Tetanus"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "Up to 45 Years"
      },
      "enrollment_count": 80,
      "start_date": "2009-01",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2014-07-25",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 4,
      "location_summary": "Durham, North Carolina • Houston, Texas • Seattle, Washington",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00707148"
    },
    {
      "nct_id": "NCT00319553",
      "title": "Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX®",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pertussis",
        "Tetanus",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "ADACEL®:Tetanus, Reduced Diphtheria and Acellular Pertussis Adsorbed",
          "type": "BIOLOGICAL"
        },
        {
          "name": "BOOSTRIX®: Tetanus, Reduced Diphtheria and Acellular Pertussis Adsorbed",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "11 Years to 18 Years"
      },
      "enrollment_count": 647,
      "start_date": "2006-05",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2012-10-05",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 10,
      "location_summary": "Annapolis, Maryland • Baltimore, Maryland • Frederick, Maryland + 6 more",
      "locations": [
        {
          "city": "Annapolis",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Frederick",
          "state": "Maryland"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00319553"
    },
    {
      "nct_id": "NCT00474526",
      "title": "A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Meningitis, Meningococcal"
      ],
      "interventions": [
        {
          "name": "Meningococcal ACWY Conjugate Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DTaP-IPV-HBV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hib",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Rotavirus",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal 7-valent Conjugate Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "HAV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "MMR-V",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DTaP",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Novartis Vaccines",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "2 Months",
        "sex": "ALL",
        "summary": "2 Months to 2 Months"
      },
      "enrollment_count": 4545,
      "start_date": "2007-03",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2014-03-24",
      "last_synced_at": "2026-10-11T07:35:52.539Z",
      "location_count": 53,
      "location_summary": "Bessemer, Alabama • Birmingham, Alabama • Downey, California + 43 more",
      "locations": [
        {
          "city": "Bessemer",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00474526"
    }
  ]
}