{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=therapy&page=115",
    "query": {
      "intervention": "therapy",
      "page": 115
    },
    "page_size": 10
  },
  "pagination": {
    "page": 115,
    "page_size": 10,
    "total_count": 84083,
    "total_pages": 8409,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=therapy&page=116&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=therapy&page=114&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-10T14:38:49.381Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01419067",
      "title": "A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Craniopharyngioma"
      ],
      "interventions": [
        {
          "name": "Radical Surgery or Limited Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Proton Therapy",
          "type": "DEVICE"
        },
        {
          "name": "^1^8F-fluorodeoxyglucose",
          "type": "DRUG"
        },
        {
          "name": "^1^1C-methionine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 112,
      "start_date": "2011-08-22",
      "completion_date": "2031-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Memphis, Tennessee",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01419067"
    },
    {
      "nct_id": "NCT00880100",
      "title": "Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cystic Fibrosis",
        "Pancreatic Insufficiency"
      ],
      "interventions": [
        {
          "name": "Ultrase® MT12",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Forest Laboratories",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "2 Years to 6 Years"
      },
      "enrollment_count": 49,
      "start_date": "2009-04",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2017-03-16",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 15,
      "location_summary": "Aurora, Colorado • Ann Arbor, Michigan • Grand Rapids, Michigan + 11 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00880100"
    },
    {
      "nct_id": "NCT02007200",
      "title": "Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Hypopharyngeal Squamous Cell Carcinoma",
        "Recurrent Laryngeal Squamous Cell Carcinoma",
        "Recurrent Laryngeal Verrucous Carcinoma",
        "Recurrent Lip and Oral Cavity Squamous Cell Carcinoma",
        "Recurrent Oral Cavity Verrucous Carcinoma",
        "Recurrent Oropharyngeal Squamous Cell Carcinoma",
        "Stage I Hypopharyngeal Squamous Cell Carcinoma",
        "Stage I Laryngeal Squamous Cell Carcinoma",
        "Stage I Laryngeal Verrucous Carcinoma",
        "Stage I Lip and Oral Cavity Squamous Cell Carcinoma",
        "Stage I Oral Cavity Verrucous Carcinoma",
        "Stage I Oropharyngeal Squamous Cell Carcinoma",
        "Stage II Hypopharyngeal Squamous Cell Carcinoma",
        "Stage II Laryngeal Squamous Cell Carcinoma",
        "Stage II Laryngeal Verrucous Carcinoma",
        "Stage II Lip and Oral Cavity Squamous Cell Carcinoma",
        "Stage II Oral Cavity Verrucous Carcinoma",
        "Stage II Oropharyngeal Squamous Cell Carcinoma",
        "Stage III Hypopharyngeal Squamous Cell Carcinoma",
        "Stage III Laryngeal Squamous Cell Carcinoma",
        "Stage III Laryngeal Verrucous Carcinoma",
        "Stage III Lip and Oral Cavity Squamous Cell Carcinoma",
        "Stage III Oral Cavity Verrucous Carcinoma",
        "Stage III Oropharyngeal Squamous Cell Carcinoma",
        "Stage IV Hypopharyngeal Squamous Cell Carcinoma",
        "Stage IVA Laryngeal Squamous Cell Carcinoma",
        "Stage IVA Laryngeal Verrucous Carcinoma",
        "Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma",
        "Stage IVA Oral Cavity Verrucous Carcinoma",
        "Stage IVA Oropharyngeal Squamous Cell Carcinoma",
        "Tongue Carcinoma"
      ],
      "interventions": [
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Soy Isoflavones",
          "type": "DRUG"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "19 Years to 79 Years"
      },
      "enrollment_count": 55,
      "start_date": "2009-07",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2016-10-24",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Ann Arbor, Michigan • Detroit, Michigan",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02007200"
    },
    {
      "nct_id": "NCT03337100",
      "title": "The Impact of Co-Dispensing Naloxone to Patients Prescribed Chronic Opioid Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose",
        "Risk Behavior"
      ],
      "interventions": [
        {
          "name": "Co-Dispensing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2017-11-27",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-03-03",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03337100"
    },
    {
      "nct_id": "NCT00061100",
      "title": "HIV Counseling Intervention for Methadone-Maintained Patients - 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Opioid-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Behavior Therapy-RISE",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard prevention Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 50,
      "start_date": "1999-10",
      "completion_date": "2003-10",
      "has_results": false,
      "last_update_posted_date": "2019-04-23",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00061100"
    },
    {
      "nct_id": "NCT02240407",
      "title": "Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pompe Disease"
      ],
      "interventions": [
        {
          "name": "Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase",
          "type": "GENETIC"
        },
        {
          "name": "Rapamycin",
          "type": "DRUG"
        },
        {
          "name": "saline",
          "type": "OTHER"
        },
        {
          "name": "Rituxan",
          "type": "DRUG"
        },
        {
          "name": "Diphenhydramine",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "LMX 4 Topical Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "GENETIC",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 2,
      "start_date": "2017-10-17",
      "completion_date": "2021-08-26",
      "has_results": false,
      "last_update_posted_date": "2022-04-05",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02240407"
    },
    {
      "nct_id": "NCT01407107",
      "title": "Dose Escalation Trial of Nitroglycerin, 5-flourouracil and Rad Therapy for Rectal Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Rectal Cancer"
      ],
      "interventions": [
        {
          "name": "Nitroglycerin 0.2 MG/HR",
          "type": "DRUG"
        },
        {
          "name": "Nitroglycerin 0.4 MG/HR",
          "type": "DRUG"
        },
        {
          "name": "Nitroglycerin 0.6 MG/HR",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 13,
      "start_date": "2011-01",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2021-01-14",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01407107"
    },
    {
      "nct_id": "NCT01018407",
      "title": "Interventions for Communication in Autism Network",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism"
      ],
      "interventions": [
        {
          "name": "Discrete Trial Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Interpersonal Developmental Approach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "33 Months",
        "maximum_age": "54 Months",
        "sex": "ALL",
        "summary": "33 Months to 54 Months"
      },
      "enrollment_count": 192,
      "start_date": "2009-12",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2024-06-14",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Baltimore, Maryland • Rochester, New York",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01018407"
    },
    {
      "nct_id": "NCT03774407",
      "title": "Vaginal Estriol in Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Neurogenic Bladder"
      ],
      "interventions": [
        {
          "name": "vaginal estriol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Texas Tech University Health Sciences Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2019-06-20",
      "completion_date": "2020-11-29",
      "has_results": true,
      "last_update_posted_date": "2022-09-21",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03774407"
    },
    {
      "nct_id": "NCT00335907",
      "title": "Protocol-driven Hemodynamic Support for Patients With Septic Shock",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shock, Septic",
        "Severe Sepsis",
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Fluid and Vasopressor Protocol",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institute of General Medical Sciences (NIGMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2006-09",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2010-08-25",
      "last_synced_at": "2026-11-10T14:38:49.381Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00335907"
    }
  ]
}