{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=thoracic+spine+manipulation",
    "query": {
      "intervention": "thoracic spine manipulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 58,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=thoracic+spine+manipulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T08:29:02.092Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02708953",
      "title": "Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Headache Disorders, Secondary"
      ],
      "interventions": [
        {
          "name": "Thoracic manipulation (Manipulation Group)",
          "type": "PROCEDURE"
        },
        {
          "name": "Thoracic Manipulation (Control wait-list)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2016-05",
      "completion_date": "2019-09-19",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02708953"
    },
    {
      "nct_id": "NCT06273969",
      "title": "Ultrasonographic Evaluation of Osteopathic Manipulation for Thoracic Outlet Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracic Outlet Syndrome"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment (OMT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "A.T. Still University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2024-04-01",
      "completion_date": "2024-04-03",
      "has_results": false,
      "last_update_posted_date": "2024-07-24",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Kirksville, Missouri",
      "locations": [
        {
          "city": "Kirksville",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06273969"
    },
    {
      "nct_id": "NCT00703248",
      "title": "The Human Immunodeficiency Virus and Osteopathic Manipulation Evaluation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatments",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "MALE",
        "summary": "18 Years to 65 Years · Male only"
      },
      "enrollment_count": null,
      "start_date": "2007-10",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2008-07-08",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Fort Lauderdale, Florida",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00703248"
    },
    {
      "nct_id": "NCT06287242",
      "title": "Validation of the Cervicothoracic Differentiation Test",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "spinal manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Hartford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-02-20",
      "completion_date": "2024-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-11",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "West Hartford, Connecticut",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06287242"
    },
    {
      "nct_id": "NCT01753271",
      "title": "Subacute Effects of Spinal Mobilization to Treat Subacromial Impingement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subacromial Impingement Syndrome"
      ],
      "interventions": [
        {
          "name": "thoracic mobilization & shoulder mobilization & exercise",
          "type": "OTHER"
        },
        {
          "name": "shoulder mobilization & exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "High Point University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-09",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-08-20",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Elizabethton, Tennessee • Johnson City, Tennessee",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Elizabethton",
          "state": "Tennessee"
        },
        {
          "city": "Johnson City",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01753271"
    },
    {
      "nct_id": "NCT06534931",
      "title": "Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Weakness"
      ],
      "interventions": [
        {
          "name": "High velocity low amplitude thoracic spine manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of New England",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-11-08",
      "completion_date": "2023-12-13",
      "has_results": false,
      "last_update_posted_date": "2024-08-02",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06534931"
    },
    {
      "nct_id": "NCT04823637",
      "title": "Evaluating for a Correlation Between Osteopathic Examination and Ultrasonography on Thoracic Spine Asymmetry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteopathic Manipulative Treatment",
        "Ultrasonography"
      ],
      "interventions": [
        {
          "name": "Ultrasonography vs Osteopathic manipulative medicine structural exam",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Midwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 74,
      "start_date": "2019-10-10",
      "completion_date": "2021-01-14",
      "has_results": false,
      "last_update_posted_date": "2021-04-01",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Glendale, Arizona",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04823637"
    },
    {
      "nct_id": "NCT02379871",
      "title": "The Effects of Mid-thoracic Manipulation on Heart Rate Variability.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurophysiological Mechanisms Underlying Spinal Manipulation"
      ],
      "interventions": [
        {
          "name": "Experimental Group",
          "type": "OTHER"
        },
        {
          "name": "Sham Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mount St. Mary's College, Los Angeles, CA",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 90,
      "start_date": "2014-01",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2015-03-05",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02379871"
    },
    {
      "nct_id": "NCT02972710",
      "title": "A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Supine thoracic spine thrust manipulation",
          "type": "OTHER"
        },
        {
          "name": "Seated thoracic spine thrust manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northern Arizona University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 76,
      "start_date": "2016-11",
      "completion_date": "2018-11",
      "has_results": false,
      "last_update_posted_date": "2018-03-13",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Flagstaff, Arizona",
      "locations": [
        {
          "city": "Flagstaff",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02972710"
    },
    {
      "nct_id": "NCT04972929",
      "title": "Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Sham Spinal Manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2023-09-15",
      "completion_date": "2025-03-12",
      "has_results": true,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-09-23T08:29:02.092Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04972929"
    }
  ]
}