{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=tiotropium+bromide&page=5", "query": { "intervention": "tiotropium bromide", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 135, "total_pages": 14, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=tiotropium+bromide&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=tiotropium+bromide&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T16:52:43.348Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00846586", "title": "Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Obstructive Pulmonary Disease (COPD)" ], "interventions": [ { "name": "Indacaterol 150 μg", "type": "DRUG" }, { "name": "Tiotropium 18 μg", "type": "DRUG" }, { "name": "Placebo to indacaterol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 1134, "start_date": "2009-03", "completion_date": "2010-03", "has_results": true, "last_update_posted_date": "2011-08-18", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 61, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Scottsdale, Arizona + 53 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00846586" }, { "nct_id": "NCT00662740", "title": "Tiotropium/Salmeterol Inhalation Powder (Spiriva Handihaler and Salmeterol Polyethylene (PE) Capsule) in Chronic Obstructive Pulmonary Disease (COPD)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Tiotropium/Salmeterol QD", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Salmeterol", "type": "DRUG" }, { "name": "Tiotropium/Salmeterol QD+ Salmeterol", "type": "DRUG" }, { "name": "Tiotropium (Spiriva®)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 220, "start_date": "2008-04-15", "completion_date": "2008-11-21", "has_results": false, "last_update_posted_date": "2023-08-23", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 20, "location_summary": "Boulder, Colorado • Wheat Ridge, Colorado • Winter Park, Florida + 16 more", "locations": [ { "city": "Boulder", "state": "Colorado" }, { "city": "Wheat Ridge", "state": "Colorado" }, { "city": "Winter Park", "state": "Florida" }, { "city": "Coeur d'Alene", "state": "Idaho" }, { "city": "South Bend", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00662740" }, { "nct_id": "NCT00240435", "title": "12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "5 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler", "type": "DEVICE" }, { "name": "10 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 491, "start_date": "2002-11", "completion_date": null, "has_results": false, "last_update_posted_date": "2013-11-01", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 14, "location_summary": "Birmingham, Alabama • Downey, California • Los Angeles, California + 11 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Downey", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Wheat Ridge", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00240435" }, { "nct_id": "NCT00557180", "title": "Examining the Link Between Obesity, Inflammation, and Response to Asthma Medications", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Asthma", "Obesity" ], "interventions": [ { "name": "Beclomethasone dipropionate HFA", "type": "DRUG" }, { "name": "Tiotropium bromide", "type": "DRUG" }, { "name": "Salmeterol xinafoate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Jewish Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2007-10", "completion_date": "2011-02", "has_results": false, "last_update_posted_date": "2020-10-22", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 10, "location_summary": "San Diego, California • San Francisco, California • Denver, Colorado + 7 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00557180" }, { "nct_id": "NCT01225913", "title": "Mechanism(s) of Airflow Limitation During Exacerbation of Asthma", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "fluticasone/salmeterol in all asthmatics", "type": "DRUG" }, { "name": "budesonide/formoterol or fluticasone/salmeterol in all asthmatics", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gelb, Arthur F., M.D.", "sponsor_class": "INDIV", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "10 Years to 80 Years" }, "enrollment_count": 50, "start_date": "2007-10", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2023-10-26", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 1, "location_summary": "Lakewood, California", "locations": [ { "city": "Lakewood", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01225913" }, { "nct_id": "NCT00144339", "title": "Evaluation of the Long- Term Effects of Spiriva on Lung Function in COPD Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "tiotropium", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 5993, "start_date": "2002-12", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-05-20", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 95, "location_summary": "Anniston, Alabama • Birmingham, Alabama • Jasper, Alabama + 82 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Jasper", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00144339" }, { "nct_id": "NCT05179512", "title": "Replication of the INSPIRE Trial in Healthcare Claims Data", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "Tiotropium", "type": "DRUG" }, { "name": "salmeterol-fluticasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 98278, "start_date": "2020-09-22", "completion_date": "2021-08-30", "has_results": false, "last_update_posted_date": "2023-07-27", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05179512" }, { "nct_id": "NCT01085045", "title": "Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PT001, PT003, and PT005 Following Chronic Dosing (7 Days) in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "PT003 MDI", "type": "DRUG" }, { "name": "PT005 MDI", "type": "DRUG" }, { "name": "Placebo MDI", "type": "DRUG" }, { "name": "Tiotropium bromide 18 μg (Spiriva Handihaler®)", "type": "DRUG" }, { "name": "Formoterol Fumarate 12 μg (Foradil® Aerolizer®)", "type": "DRUG" }, { "name": "PT001 MDI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pearl Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 118, "start_date": "2010-03", "completion_date": "2010-11", "has_results": true, "last_update_posted_date": "2017-04-26", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 4, "location_summary": "Clearwater, Florida • Charlotte, North Carolina • Medford, Oregon + 1 more", "locations": [ { "city": "Clearwater", "state": "Florida" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Medford", "state": "Oregon" }, { "city": "Spartanburg", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01085045" }, { "nct_id": "NCT06254664", "title": "Open Label Study to Assess the Effect of Patient Use and Robustness of Tiotropium 18ug Inhalation Powder, Hard Capsule,Zephir Inhaler Device", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "COPD" ], "interventions": [ { "name": "Tiotropium 18 µg inhalation powder, hard capsule", "type": "DRUG" }, { "name": "Zephir inhaler", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Xiromed LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "40 Years to 75 Years" }, "enrollment_count": 116, "start_date": "2022-10-03", "completion_date": "2023-10-27", "has_results": false, "last_update_posted_date": "2024-02-12", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 8, "location_summary": "Fort Myers, Florida • Kissimmee, Florida • Miami, Florida + 2 more", "locations": [ { "city": "Fort Myers", "state": "Florida" }, { "city": "Kissimmee", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06254664" }, { "nct_id": "NCT01122680", "title": "Efficacy and Safety of 3 Doses of Tiotropium Compared to Placebo in Adolescents (12 to 17 Yrs) With Moderate Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "tiotropium bromide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "12 Years to 17 Years" }, "enrollment_count": 105, "start_date": "2010-05", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-05-16", "last_synced_at": "2026-10-04T16:52:43.348Z", "location_count": 5, "location_summary": "Denver, Colorado • Columbia, Missouri • Warrensburg, Missouri + 2 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Columbia", "state": "Missouri" }, { "city": "Warrensburg", "state": "Missouri" }, { "city": "Boys Town", "state": "Nebraska" }, { "city": "Canton", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01122680" } ] }