{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=transcranial+ultrasound&page=2",
    "query": {
      "intervention": "transcranial ultrasound",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 124,
    "total_pages": 13,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=transcranial+ultrasound&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=transcranial+ultrasound&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T03:59:51.596Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04579692",
      "title": "MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trigeminal Neuralgia"
      ],
      "interventions": [
        {
          "name": "ExAblate Transcranial treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-08-16",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04579692"
    },
    {
      "nct_id": "NCT01404052",
      "title": "Effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound on Osteoarthritis Pain of the Knee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 38,
      "start_date": "2011-01",
      "completion_date": "2014-07-30",
      "has_results": false,
      "last_update_posted_date": "2020-04-24",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01404052"
    },
    {
      "nct_id": "NCT04583163",
      "title": "Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cerebral Aneurysm",
        "Stroke",
        "Vasospasm, Cerebral",
        "Subarachnoid Hemorrhage, Aneurysmal",
        "Aneurysmal Subarachnoid Hemorrhage",
        "Cerebral Ischemia"
      ],
      "interventions": [
        {
          "name": "Transcranial Doppler",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Hackensack Meridian Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2020-09-22",
      "completion_date": "2022-08-12",
      "has_results": true,
      "last_update_posted_date": "2025-04-15",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Hackensack, New Jersey",
      "locations": [
        {
          "city": "Hackensack",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04583163"
    },
    {
      "nct_id": "NCT05417555",
      "title": "Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Amnestic Mild Cognitive Disorder",
        "Deep Brain Stimulation",
        "Mild Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Low-Intensity Focused Ultrasound Pulsation (LIFUP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 120,
      "start_date": "2022-09-01",
      "completion_date": "2026-09-15",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05417555"
    },
    {
      "nct_id": "NCT01019343",
      "title": "Physiological Investigations of Movement Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Tourette's Syndrome",
        "Tic Disorders",
        "Dystonia",
        "Movement Disorders"
      ],
      "interventions": [
        {
          "name": "Transcranial Direct Current Stimulation (tDCS)",
          "type": "PROCEDURE"
        },
        {
          "name": "Eye-tracking Device",
          "type": "DEVICE"
        },
        {
          "name": "Pulsed vibrator",
          "type": "DEVICE"
        },
        {
          "name": "Gait Trainer Treadmill (GTT)",
          "type": "OTHER"
        },
        {
          "name": "Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA",
          "type": "OTHER"
        },
        {
          "name": "iMobility",
          "type": "DEVICE"
        },
        {
          "name": "QMAT",
          "type": "DEVICE"
        },
        {
          "name": "Treadmill Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Arm Intellistretch Device",
          "type": "DEVICE"
        },
        {
          "name": "Transcranial Sonography (TCS)",
          "type": "PROCEDURE"
        },
        {
          "name": "Behavioral tasks",
          "type": "OTHER"
        },
        {
          "name": "TMS single/paired pulse",
          "type": "PROCEDURE"
        },
        {
          "name": "MEG",
          "type": "PROCEDURE"
        },
        {
          "name": "EEG",
          "type": "PROCEDURE"
        },
        {
          "name": "MRI techniques",
          "type": "PROCEDURE"
        },
        {
          "name": "Peripheral Nerve Stimulation",
          "type": "PROCEDURE"
        },
        {
          "name": "EMG",
          "type": "PROCEDURE"
        },
        {
          "name": "Trancutaneous spinal direct current stimulation (tsDCS)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1273,
      "start_date": "2009-12-08",
      "completion_date": "2020-10-09",
      "has_results": false,
      "last_update_posted_date": "2026-09-18",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01019343"
    },
    {
      "nct_id": "NCT05475340",
      "title": "Open Label Study for the Use of Transcranial Ultrasound Treatment of Tremor",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Tremor",
        "Parkinson Disease",
        "Essential Tremor"
      ],
      "interventions": [
        {
          "name": "Focused Ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Neurological Associates of West Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 50,
      "start_date": "2022-07-13",
      "completion_date": "2024-08-13",
      "has_results": false,
      "last_update_posted_date": "2023-01-26",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05475340"
    },
    {
      "nct_id": "NCT02246374",
      "title": "ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "ExAblate Transcranial System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "InSightec",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2014-09",
      "completion_date": "2021-05-18",
      "has_results": true,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02246374"
    },
    {
      "nct_id": "NCT04218084",
      "title": "Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Voxelotor",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "2 Years to 14 Years"
      },
      "enrollment_count": 236,
      "start_date": "2020-11-11",
      "completion_date": "2024-11-06",
      "has_results": true,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 13,
      "location_summary": "Washington D.C., District of Columbia • Miami, Florida • Atlanta, Georgia + 5 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04218084"
    },
    {
      "nct_id": "NCT07852923",
      "title": "Examination of Transcranial Focused Ultrasound on Brain Activity in Adults With Cocaine Use Disorder",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cocaine Use Disorder (CUD)"
      ],
      "interventions": [
        {
          "name": "tFUS",
          "type": "DEVICE"
        },
        {
          "name": "Sham tFUS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mary Phillips, MD MD (Cantab)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 57,
      "start_date": "2026-12-15",
      "completion_date": "2028-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-10-01",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07852923"
    },
    {
      "nct_id": "NCT07508722",
      "title": "Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers",
        "no Condition, Basic Science"
      ],
      "interventions": [
        {
          "name": "Transcranial Focused Ultrasound Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Electroencephalography",
          "type": "DEVICE"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-10-01",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-10-08T03:59:51.596Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07508722"
    }
  ]
}