{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=vaginal+progesterone+suppository",
    "query": {
      "intervention": "vaginal progesterone suppository"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=vaginal+progesterone+suppository&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T20:40:52.956Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01546454",
      "title": "Relationship Between the Menstrual Cycle and Heart Disease in Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Heart Disease"
      ],
      "interventions": [
        {
          "name": "Ethinyl Estradiol-Levonorgestrel combination",
          "type": "DRUG"
        },
        {
          "name": "leuprolide acetate",
          "type": "DRUG"
        },
        {
          "name": "Estradiol",
          "type": "DRUG"
        },
        {
          "name": "Progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 40 Years · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2012-02",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01546454"
    },
    {
      "nct_id": "NCT03440359",
      "title": "Vaginal Progesterone Supplementation in Women With PCOS Undergoing Ovulation Induction With Letrozole",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Polycystic Ovary Syndrome"
      ],
      "interventions": [
        {
          "name": "Progesterone Vaginal Gel 8%",
          "type": "DRUG"
        },
        {
          "name": "Letrozole Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "pelvic ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ovidrel 250 MCG Per 0.5 ML Prefilled Syringe",
          "type": "DRUG"
        },
        {
          "name": "Intrauterine insemination or timed intercourse",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Eastern Virginia Medical School",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 40 Years · Female only"
      },
      "enrollment_count": 52,
      "start_date": "2012-07-06",
      "completion_date": "2017-12-30",
      "has_results": false,
      "last_update_posted_date": "2018-02-26",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440359"
    },
    {
      "nct_id": "NCT01058382",
      "title": "Progesterone Support of FET",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Frozen Embryo Pregnancy Rate"
      ],
      "interventions": [
        {
          "name": "Progesterone Vaginal Suppositories",
          "type": "DRUG"
        },
        {
          "name": "Intramuscular Progesterone-in-Oil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Charles Coddington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 50 Years · Female only"
      },
      "enrollment_count": 57,
      "start_date": "2010-02",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2013-05-10",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01058382"
    },
    {
      "nct_id": "NCT00579553",
      "title": "Comparing IM vs. Vaginal Progesterone for Pre-term Birth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Premature",
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Intramuscular Progesterone",
          "type": "DRUG"
        },
        {
          "name": "Vaginal Progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 174,
      "start_date": "2006-10",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2021-05-19",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00579553"
    },
    {
      "nct_id": "NCT02518594",
      "title": "A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Short Cervical Length"
      ],
      "interventions": [
        {
          "name": "Vaginal progesterone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Arabin Pessary",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The George Washington University Biostatistics Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 1311,
      "start_date": "2015-11-13",
      "completion_date": "2025-02-18",
      "has_results": true,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 16,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Denver, Colorado + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02518594"
    },
    {
      "nct_id": "NCT03251729",
      "title": "Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short Cervix",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Cervical cerclage",
          "type": "PROCEDURE"
        },
        {
          "name": "Vaginal progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 93,
      "start_date": "2017-09-22",
      "completion_date": "2024-02-20",
      "has_results": false,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03251729"
    },
    {
      "nct_id": "NCT01380158",
      "title": "Preventing Preterm Birth With a Pessary",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Cup pessary (Bioteque America, Inc)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2011-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2021-02-17",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01380158"
    },
    {
      "nct_id": "NCT02901626",
      "title": "A Randomized Trial of Pessary in Singleton Pregnancies With a Short Cervix",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Short Cervix",
        "Preterm Delivery"
      ],
      "interventions": [
        {
          "name": "Arabin Cervical Pessary",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The George Washington University Biostatistics Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 544,
      "start_date": "2017-02-14",
      "completion_date": "2022-05-10",
      "has_results": true,
      "last_update_posted_date": "2026-06-23",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • Chicago, Illinois • New York, New York + 9 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02901626"
    },
    {
      "nct_id": "NCT01954095",
      "title": "The Impact of Vaginal and IM Progestins on the Cervix",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preterm Birth",
        "Short Cervical Length"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 89,
      "start_date": "2013-08",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2015-12-02",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 4,
      "location_summary": "Indianapolis, Indiana • Pittsburgh, Pennsylvania • Galveston, Texas + 1 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Galveston",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01954095"
    },
    {
      "nct_id": "NCT01840228",
      "title": "Vaginal Progesterone for the Prevention of Preterm Birth in Women With Arrested Preterm Labor",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth",
        "Obstetric Labor, Premature"
      ],
      "interventions": [
        {
          "name": "Micronized progesterone suppository",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2013-05",
      "completion_date": "2018-05-07",
      "has_results": true,
      "last_update_posted_date": "2019-06-18",
      "last_synced_at": "2026-09-04T20:40:52.956Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01840228"
    }
  ]
}