{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?page=25&q=gene+therapy", "query": { "q": "gene therapy", "page": 25 }, "page_size": 10 }, "pagination": { "page": 25, "page_size": 10, "total_count": 5852, "total_pages": 586, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?page=26&q=gene+therapy&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?page=24&q=gene+therapy&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-15T20:44:16.567Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02223819", "title": "Crizotinib in High-Risk Uveal Melanoma Following Definitive Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Uveal Melanoma" ], "interventions": [ { "name": "Crizotinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 34, "start_date": "2015-03", "completion_date": "2019-07-03", "has_results": true, "last_update_posted_date": "2023-12-06", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 4, "location_summary": "Miami Beach, Florida • New York, New York • Columbus, Ohio", "locations": [ { "city": "Miami Beach", "state": "Florida" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02223819" }, { "nct_id": "NCT02009436", "title": "Azacitidine in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Recurrent Non-Small Cell Lung Carcinoma", "Stage IV Non-Small Cell Lung Cancer" ], "interventions": [ { "name": "Azacitidine", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pharmacological Study", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2015-02-09", "completion_date": "2018-07-18", "has_results": false, "last_update_posted_date": "2020-02-07", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02009436" }, { "nct_id": "NCT02197234", "title": "Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Non Small Cell Lung Cancer" ], "interventions": [ { "name": "Pharmacokinetic sampling - AZD9291", "type": "PROCEDURE" }, { "name": "Simvastatin", "type": "DRUG" }, { "name": "AZD9291 tablet dosing", "type": "DRUG" }, { "name": "Pharmacokinetic sampling - simvastatin", "type": "PROCEDURE" }, { "name": "Pharmacokinetic sampling - AZ5140 and AZ7550", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "130 Years", "sex": "ALL", "summary": "18 Years to 130 Years" }, "enrollment_count": 52, "start_date": "2014-12-22", "completion_date": "2024-06-03", "has_results": true, "last_update_posted_date": "2025-11-20", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02197234" }, { "nct_id": "NCT01670500", "title": "Cisplatin vs. Doxorubicin/Cyclophosphamide in BrCa", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "Cisplatin", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 118, "start_date": "2012-10", "completion_date": "2025-02-02", "has_results": true, "last_update_posted_date": "2026-05-05", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 15, "location_summary": "Aurora, Colorado • Derby, Connecticut • Guilford, Connecticut + 9 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Derby", "state": "Connecticut" }, { "city": "Guilford", "state": "Connecticut" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT01670500" }, { "nct_id": "NCT00777036", "title": "A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to Imatinib", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leukemia" ], "interventions": [ { "name": "Dasatinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "18 Years", "sex": "ALL", "summary": "1 Day to 18 Years" }, "enrollment_count": 133, "start_date": "2009-03-20", "completion_date": "2025-01-27", "has_results": true, "last_update_posted_date": "2025-08-29", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 35, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Long Beach, California + 11 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Long Beach", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00777036" }, { "nct_id": "NCT06253507", "title": "pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "p47", "Autosomal Recessive", "Chronic Granulomatous Disease" ], "interventions": [ { "name": "Cryopreserved Autologous CD34+ cells transduced with pCCLCHIM-p47", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "3 Years to 65 Years" }, "enrollment_count": 10, "start_date": "2024-06-25", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06253507" }, { "nct_id": "NCT00783575", "title": "Genetic Markers as Predictors of Phenotypes in Pediatric Onset Crohn's Disease", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Crohn's Disease", "Ulcerative Colitis", "Inflammatory Bowel Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 0, "start_date": "2002-10", "completion_date": "2015-01", "has_results": false, "last_update_posted_date": "2015-08-24", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT00783575" }, { "nct_id": "NCT02189057", "title": "A Pharmacokinetic/Pharmacodynamic Genetic Variation Treatment Algorithm Versus Treatment As Usual for Management Of Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression", "Mood Disorder", "Bipolar" ], "interventions": [ { "name": "AssureRx GeneSight genotyping results", "type": "OTHER" }, { "name": "Treatment as usual", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 160, "start_date": "2014-11", "completion_date": "2018-10-19", "has_results": false, "last_update_posted_date": "2018-10-22", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02189057" }, { "nct_id": "NCT06885424", "title": "A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Solid Tumor Cancer", "Solid Tumor, Unspecified, Adult", "Colorectal Carcinoma", "Colorectal Carcinoma (CRC)", "Non Small Cell Lung Cancer", "Small Cell Lung Cancer ( SCLC )", "Pancreatic Cancer", "NSCLC", "Mesothelioma", "Ovarian Cancer", "Ovarian Carcinoma", "Head and Neck (HNSCC)", "Head and Neck Cancer", "Renal Cell Carcinoma (Kidney Cancer)", "Triple Negative Breast Cancer (TNBC)" ], "interventions": [ { "name": "No additional intervention administered in this long term follow-up study", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "A2 Biotherapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2025-07-31", "completion_date": "2040-03-31", "has_results": false, "last_update_posted_date": "2026-05-20", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 3, "location_summary": "Gilbert, Arizona • Rochester, Minnesota • New York, New York", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06885424" }, { "nct_id": "NCT05536388", "title": "Drug Discovery for Parkinson's With Mutations in the GBA Gene", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Parkinson Disease", "Gaucher Disease", "Healthy", "GBA Gene Mutation" ], "interventions": [ { "name": "Biological Sample Collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "New York Stem Cell Foundation Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2022-07-15", "completion_date": "2025-07-15", "has_results": false, "last_update_posted_date": "2025-03-03", "last_synced_at": "2026-10-15T20:44:16.567Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05536388" } ] }