{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?page=51&q=gene+therapy", "query": { "q": "gene therapy", "page": 51 }, "page_size": 10 }, "pagination": { "page": 51, "page_size": 10, "total_count": 5852, "total_pages": 586, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?page=52&q=gene+therapy&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?page=50&q=gene+therapy&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-17T10:02:26.457Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02822378", "title": "Dried Plums and Bone Health in Postmenopausal Women", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postmenopausal Osteoporosis" ], "interventions": [ { "name": "Dried Plum", "type": "DIETARY_SUPPLEMENT" }, { "name": "Calcium supplement", "type": "DIETARY_SUPPLEMENT" }, { "name": "Vitamin D supplement", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Penn State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "55 Years to 75 Years · Female only" }, "enrollment_count": 322, "start_date": "2016-06-01", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-07-06", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "University Park, Pennsylvania", "locations": [ { "city": "University Park", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02822378" }, { "nct_id": "NCT04675710", "title": "Pembrolizumab, Dabrafenib, and Trametinib Before Surgery for the Treatment of BRAF-Mutated Anaplastic Thyroid Cancer", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Thyroid Gland Anaplastic Carcinoma", "Thyroid Gland Squamous Cell Carcinoma" ], "interventions": [ { "name": "Conventional Surgery", "type": "PROCEDURE" }, { "name": "Dabrafenib", "type": "DRUG" }, { "name": "Intensity-Modulated Radiation Therapy", "type": "RADIATION" }, { "name": "Pembrolizumab", "type": "BIOLOGICAL" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Trametinib", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG", "RADIATION", "BIOLOGICAL", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2021-06-24", "completion_date": "2028-10-30", "has_results": false, "last_update_posted_date": "2026-10-08", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 6, "location_summary": "Stanford, California • Ann Arbor, Michigan • Rochester, Minnesota + 3 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04675710" }, { "nct_id": "NCT02435940", "title": "Inherited Retinal Degenerative Disease Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Eye Diseases Hereditary", "Retinal Disease", "Achromatopsia", "Bardet-Biedl Syndrome", "Bassen-Kornzweig Syndrome", "Batten Disease", "Best Disease", "Choroidal Dystrophy", "Choroideremia", "Cone Dystrophy", "Cone-Rod Dystrophy", "Congenital Stationary Night Blindness", "Enhanced S-Cone Syndrome", "Fundus Albipunctatus", "Goldmann-Favre Syndrome", "Gyrate Atrophy", "Juvenile Macular Degeneration", "Kearns-Sayre Syndrome", "Leber Congenital Amaurosis", "Refsum Syndrome", "Retinitis Pigmentosa", "Retinitis Punctata Albescens", "Retinoschisis", "Rod-Cone Dystrophy", "Rod Dystrophy", "Rod Monochromacy", "Stargardt Disease", "Usher Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Foundation Fighting Blindness", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 20000, "start_date": "2014-06", "completion_date": "2037-06", "has_results": false, "last_update_posted_date": "2026-05-19", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "Columbia, Maryland", "locations": [ { "city": "Columbia", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02435940" }, { "nct_id": "NCT06997497", "title": "A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Colon Adenocarcinoma", "Rectal Adenocarcinoma" ], "interventions": [ { "name": "Calderasib", "type": "DRUG" }, { "name": "Oxaliplatin", "type": "DRUG" }, { "name": "Leucovorin/levofolinate calcium", "type": "DRUG" }, { "name": "5-Fluorouracil", "type": "DRUG" }, { "name": "Cetuximab", "type": "BIOLOGICAL" }, { "name": "Bevacizumab", "type": "DRUG" }, { "name": "Bevacizumab biosimilar", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 477, "start_date": "2025-07-16", "completion_date": "2030-10-27", "has_results": false, "last_update_posted_date": "2026-10-07", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 48, "location_summary": "Phoenix, Arizona • Fountain Valley, California • Los Angeles, California + 43 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06997497" }, { "nct_id": "NCT04896580", "title": "IIT2020-20-SHIRAZIP-WALK: Nature Walks", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Breast Cancer", "Cancer", "Lymphoma", "Leukemia", "Prostate Cancer", "Thyroid Cancer", "Hematologic Malignancy", "Non-hodgkin Lymphoma" ], "interventions": [ { "name": "Nature based exercise", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 20, "start_date": "2021-06-21", "completion_date": "2023-05-18", "has_results": false, "last_update_posted_date": "2025-02-26", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04896580" }, { "nct_id": "NCT00787280", "title": "Diet, Imaging and Energy Balance Trial (DIET)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Low Carbohydrate Ketogenic Diet (LCKD)", "type": "BEHAVIORAL" }, { "name": "Low Fat Diet (LFD)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 51, "start_date": "2008-08", "completion_date": "2010-11", "has_results": false, "last_update_posted_date": "2013-02-20", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00787280" }, { "nct_id": "NCT00700778", "title": "Recombinant Human Chorionic Gonadotropin in Preventing Breast Cancer in Premenopausal Women With BRCA1 Mutations", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "BRCA1 Mutation", "Breast Cancer" ], "interventions": [ { "name": "recombinant human chorionic gonadotropin", "type": "BIOLOGICAL" }, { "name": "microarray analysis", "type": "GENETIC" }, { "name": "immunohistochemistry staining method", "type": "OTHER" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "needle biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "GENETIC", "OTHER", "PROCEDURE" ], "sponsor": "Fox Chase Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "40 Years", "sex": "FEMALE", "summary": "20 Years to 40 Years · Female only" }, "enrollment_count": 2, "start_date": "2008-07", "completion_date": "2014-03", "has_results": true, "last_update_posted_date": "2021-01-25", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 2, "location_summary": "Rochester, Minnesota • Philadelphia, Pennsylvania", "locations": [ { "city": "Rochester", "state": "Minnesota" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00700778" }, { "nct_id": "NCT00088413", "title": "PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Adenocarcinoma", "Colorectal Cancer", "Ovarian Cancer", "Breast Cancer" ], "interventions": [ { "name": "PANVAC-V", "type": "BIOLOGICAL" }, { "name": "PANVAC-F", "type": "BIOLOGICAL" }, { "name": "Sargramostim (GM-CSF, Leukine)", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 51, "start_date": "2004-07-21", "completion_date": "2018-05-31", "has_results": true, "last_update_posted_date": "2019-04-16", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00088413" }, { "nct_id": "NCT07025148", "title": "Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Coronary Arterial Disease (CAD)", "Percutaneous Coronary Intervention (PCI)" ], "interventions": [ { "name": "Prasugrel", "type": "DRUG" }, { "name": "Clopidogrel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2025-10-01", "completion_date": "2027-11-01", "has_results": false, "last_update_posted_date": "2026-10-07", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07025148" }, { "nct_id": "NCT00079378", "title": "Decitabine and Valproic Acid in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities", "Adult Acute Myeloid Leukemia With Del(5q)", "Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)", "Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)", "Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)", "Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)", "Recurrent Adult Acute Myeloid Leukemia", "Recurrent Small Lymphocytic Lymphoma", "Refractory Chronic Lymphocytic Leukemia", "Untreated Adult Acute Myeloid Leukemia" ], "interventions": [ { "name": "decitabine", "type": "DRUG" }, { "name": "valproic acid", "type": "DRUG" }, { "name": "pharmacological study", "type": "OTHER" }, { "name": "laboratory biomarker analysis", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 84, "start_date": "2004-02", "completion_date": null, "has_results": false, "last_update_posted_date": "2013-09-30", "last_synced_at": "2026-10-17T10:02:26.457Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00079378" } ] }