{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?q=renal+denervation",
    "query": {
      "q": "renal denervation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 45,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?q=renal+denervation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T22:01:16.214Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01972139",
      "title": "Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Vascular Diseases",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Renal Denervation using the Symplicity Renal Denervation System",
          "type": "DEVICE"
        },
        {
          "name": "Sham Renal Denervation",
          "type": "OTHER"
        },
        {
          "name": "Renal Angiography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Medtronic Vascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 44,
      "start_date": "2013-10",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-04-26",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Durham, North Carolina • Charleston, South Carolina",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01972139"
    },
    {
      "nct_id": "NCT06559891",
      "title": "THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "TIVUS™ Renal Denervation System",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "SoniVie Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 261,
      "start_date": "2024-10-03",
      "completion_date": "2028-08-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 33,
      "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Jonesboro, Arkansas + 29 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06559891"
    },
    {
      "nct_id": "NCT01117025",
      "title": "Combined Treatment of Resistant Hypertension and Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypertension, Resistant to Conventional Therapy",
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Circumferential PV isolation",
          "type": "PROCEDURE"
        },
        {
          "name": "Circumferential PVI+renal denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 26,
      "start_date": "2010-04",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2013-07-10",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01117025"
    },
    {
      "nct_id": "NCT07083765",
      "title": "Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hypertension",
        "Hypertension,Essential"
      ],
      "interventions": [
        {
          "name": "Dehydrated Alcohol Injection, USP",
          "type": "DRUG"
        },
        {
          "name": "Sham procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Ablative Solutions, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 142,
      "start_date": "2025-09-01",
      "completion_date": "2027-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07083765"
    },
    {
      "nct_id": "NCT01873352",
      "title": "Renal Artery Denervation In Addition to Catheter Ablation To Eliminate Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "catheter ablation",
          "type": "PROCEDURE"
        },
        {
          "name": "renal sympathetic denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 302,
      "start_date": "2013-06-20",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2019-09-04",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 1,
      "location_summary": "Short Hills, New Jersey",
      "locations": [
        {
          "city": "Short Hills",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01873352"
    },
    {
      "nct_id": "NCT01897545",
      "title": "Combined Treatment of Arterial Hypertension and Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Arterial Hypertension",
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Circumferential PV isolation",
          "type": "PROCEDURE"
        },
        {
          "name": "PV isolation+renal denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2012-04",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-10-09",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01897545"
    },
    {
      "nct_id": "NCT05372679",
      "title": "REDUCED 1 - Renal Denervation Using Ultrasonic Catheter EmitteD Energy Study /",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Uncontrolled Stage 2 Hypertension"
      ],
      "interventions": [
        {
          "name": "Renal denervation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SoniVie Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 25,
      "start_date": "2022-11-11",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 9,
      "location_summary": "Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 6 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05372679"
    },
    {
      "nct_id": "NCT05198674",
      "title": "SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Vascular Diseases",
        "Cardiovascular Diseases",
        "Chronic Kidney Diseases",
        "Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Renal Denervation (Symplicity Spyral™)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Vascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1899,
      "start_date": "2021-10-20",
      "completion_date": "2029-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 79,
      "location_summary": "Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 70 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05198674"
    },
    {
      "nct_id": "NCT03614260",
      "title": "The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Vascular Diseases",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Paradise Renal Denervation System",
          "type": "DEVICE"
        },
        {
          "name": "Renal Angiogram",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "ReCor Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 225,
      "start_date": "2018-12-14",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2025-04-04",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 28,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Bridgeport, Connecticut + 24 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03614260"
    },
    {
      "nct_id": "NCT01959997",
      "title": "Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Arterial Hypertension"
      ],
      "interventions": [
        {
          "name": "Redo PVI",
          "type": "PROCEDURE"
        },
        {
          "name": "PVI + RDN",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 60,
      "start_date": "2013-09",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2015-09-23",
      "last_synced_at": "2026-07-24T22:01:16.214Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01959997"
    }
  ]
}