{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?sponsor=Arrowhead+Pharmaceuticals", "query": { "sponsor": "Arrowhead Pharmaceuticals" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 16, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?sponsor=Arrowhead+Pharmaceuticals&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-03T22:51:39.785Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04998201", "title": "Study of Plozasiran (ARO-APOC3) in Adults With Mixed Dyslipidemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Mixed Dyslipidemia" ], "interventions": [ { "name": "ARO-APOC3", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 353, "start_date": "2021-09-28", "completion_date": "2023-08-14", "has_results": true, "last_update_posted_date": "2026-04-14", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 15, "location_summary": "Beverly Hills, California • Northridge, California • Boca Raton, Florida + 11 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Northridge", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Miami Springs", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04998201" }, { "nct_id": "NCT06347133", "title": "Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertriglyceridemia" ], "interventions": [ { "name": "Plozasiran Injection", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1456, "start_date": "2024-05-21", "completion_date": "2026-09-08", "has_results": false, "last_update_posted_date": "2026-09-25", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 97, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Beverly Hills, California + 80 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Canoga Park", "state": "California" }, { "city": "Garden Grove", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06347133" }, { "nct_id": "NCT06347003", "title": "Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Severe Hypertriglyceridemia" ], "interventions": [ { "name": "Plozasiran Injection", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 446, "start_date": "2024-07-22", "completion_date": "2026-09", "has_results": false, "last_update_posted_date": "2026-07-15", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 52, "location_summary": "Garden Grove, California • Lake Forest, California • Montclair, California + 42 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "Lake Forest", "state": "California" }, { "city": "Montclair", "state": "California" }, { "city": "Panorama City", "state": "California" }, { "city": "Redding", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06347003" }, { "nct_id": "NCT05089084", "title": "Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Familial Chylomicronemia" ], "interventions": [ { "name": "Plozasiran", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 75, "start_date": "2021-12-14", "completion_date": "2026-04-21", "has_results": true, "last_update_posted_date": "2026-06-05", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 9, "location_summary": "Boca Raton, Florida • Suwanee, Georgia • Indianapolis, Indiana + 5 more", "locations": [ { "city": "Boca Raton", "state": "Florida" }, { "city": "Suwanee", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Elkridge", "state": "Maryland" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05089084" }, { "nct_id": "NCT07037771", "title": "A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Homozygous Familial Hypercholesterolemia" ], "interventions": [ { "name": "zodasiran Injection", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 70, "start_date": "2025-06-17", "completion_date": "2027-08-20", "has_results": false, "last_update_posted_date": "2026-08-12", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 4, "location_summary": "Park Ridge, Illinois • New York, New York • Cincinnati, Ohio + 1 more", "locations": [ { "city": "Park Ridge", "state": "Illinois" }, { "city": "New York", "state": "New York" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07037771" }, { "nct_id": "NCT05413135", "title": "Study of ARO-APOC3 in Adults With Dyslipidemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dyslipidemias" ], "interventions": [ { "name": "ARO-APOC3", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 418, "start_date": "2022-07-07", "completion_date": "2025-09-22", "has_results": false, "last_update_posted_date": "2026-05-12", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 30, "location_summary": "Beverly Hills, California • Northridge, California • Palm Springs, California + 24 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Northridge", "state": "California" }, { "city": "Palm Springs", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Fort Lauderdale", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05413135" }, { "nct_id": "NCT04720534", "title": "Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Severe Hypertriglyceridemia" ], "interventions": [ { "name": "ARO-APOC3", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 229, "start_date": "2021-05-31", "completion_date": "2023-08-31", "has_results": true, "last_update_posted_date": "2026-03-24", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 33, "location_summary": "Beverly Hills, California • Palm Springs, California • Boca Raton, Florida + 26 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Palm Springs", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04720534" }, { "nct_id": "NCT02452528", "title": "Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B Virus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "ARC-520", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Entecavir", "type": "DRUG" }, { "name": "Tenofovir", "type": "DRUG" }, { "name": "diphenhydramine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 4, "start_date": "2015-08", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2025-11-03", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 4, "location_summary": "San Francisco, California • Miami, Florida • New York, New York + 1 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "New York", "state": "New York" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02452528" }, { "nct_id": "NCT03945292", "title": "Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alpha 1-Antitrypsin Deficiency" ], "interventions": [ { "name": "Fazisiran Injection", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 40, "start_date": "2019-08-07", "completion_date": "2023-09-18", "has_results": true, "last_update_posted_date": "2025-11-04", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 16, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 13 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03945292" }, { "nct_id": "NCT04832971", "title": "Study of ARO-ANG3 in Adults With Mixed Dyslipidemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Mixed Dyslipidemia" ], "interventions": [ { "name": "ARO-ANG3", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 204, "start_date": "2021-06-28", "completion_date": "2024-09-25", "has_results": true, "last_update_posted_date": "2025-12-03", "last_synced_at": "2026-10-03T22:51:39.785Z", "location_count": 13, "location_summary": "Huntington Park, California • Hialeah, Florida • Miami, Florida + 10 more", "locations": [ { "city": "Huntington Park", "state": "California" }, { "city": "Hialeah", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Port Orange", "state": "Florida" }, { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04832971" } ] }