{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?sponsor=Children%27s+Hospital+of+Orange+County",
    "query": {
      "sponsor": "Children's Hospital of Orange County"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 44,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?sponsor=Children%27s+Hospital+of+Orange+County&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-05T11:36:31.593Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04978571",
      "title": "Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Concussion Syndrome",
        "COVID Long-Haul",
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "percutaneous electrical nerve-field stimulation, PENFS",
          "type": "DEVICE"
        },
        {
          "name": "percutaneous electrical nerve-field stimulation, PENFS (sham device)",
          "type": "DEVICE"
        },
        {
          "name": "percutaneous electrical nerve-field stimulation, PENFS (COVID active device)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Orange County",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "11 Years to 18 Years"
      },
      "enrollment_count": 125,
      "start_date": "2021-02-01",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04978571"
    },
    {
      "nct_id": "NCT04943848",
      "title": "rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diffuse Intrinsic Pontine Glioma",
        "Diffuse Midline Glioma, H3 K27M-Mutant"
      ],
      "interventions": [
        {
          "name": "rHSC-DIPGVax",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Balstilimab",
          "type": "DRUG"
        },
        {
          "name": "Zalifrelimab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Months to 18 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-01-10",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 3,
      "location_summary": "Orange, California • Chicago, Illinois • Boston, Massachusetts",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04943848"
    },
    {
      "nct_id": "NCT07361536",
      "title": "Cardiac Structure and Function in MPS",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "MPS I",
        "MPS IV A",
        "MPS - Mucopolysaccharidosis",
        "MPS IVA"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital of Orange County",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "0 Years to 99 Years"
      },
      "enrollment_count": 240,
      "start_date": "2025-09-01",
      "completion_date": "2030-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 3,
      "location_summary": "Orange, California • Minneapolis, Minnesota • St Louis, Missouri",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07361536"
    },
    {
      "nct_id": "NCT01805778",
      "title": "Preventing Cardiac Sequelae in Pediatric Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anthracycline-induced Cardiotoxicity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Hospital for Sick Children",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 1128,
      "start_date": "2012-12",
      "completion_date": "2018-09",
      "has_results": false,
      "last_update_posted_date": "2019-07-08",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01805778"
    },
    {
      "nct_id": "NCT02860702",
      "title": "Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Defect"
      ],
      "interventions": [
        {
          "name": "Human Milk Derived Fortifier",
          "type": "OTHER"
        },
        {
          "name": "Human/Bovine Milk",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "1 Day to 7 Days"
      },
      "enrollment_count": 16,
      "start_date": "2016-07",
      "completion_date": "2022-10-06",
      "has_results": false,
      "last_update_posted_date": "2023-09-26",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 12,
      "location_summary": "Loma Linda, California • Los Angeles, California • Orange, California + 9 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02860702"
    },
    {
      "nct_id": "NCT00640289",
      "title": "Clinical Trial of Factor XIII (FXIII) Concentrate",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemophilia",
        "Factor XIII Deficiency"
      ],
      "interventions": [
        {
          "name": "Fibrogammin P",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital of Orange County",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 72,
      "start_date": "2000-01",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2018-11-07",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00640289"
    },
    {
      "nct_id": "NCT05213676",
      "title": "De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Congenital Diaphragmatic Hernia"
      ],
      "interventions": [
        {
          "name": "Inhaled Nitric Oxide (iNO) use",
          "type": "DRUG"
        },
        {
          "name": "De-implementation of Inhaled Nitric Oxide (iNO) use",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Months",
        "maximum_age": "1 Month",
        "sex": "ALL",
        "summary": "0 Months to 1 Month"
      },
      "enrollment_count": 600,
      "start_date": "2025-11-01",
      "completion_date": "2031-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Irvine, California + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05213676"
    },
    {
      "nct_id": "NCT00544427",
      "title": "Near Infrared Optical Coherence Tomography of the Upper Aero-Digestive Tract",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Disorder of Upper Digestive Tract"
      ],
      "interventions": [
        {
          "name": "Optical coherence tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Day and older"
      },
      "enrollment_count": 0,
      "start_date": "2003-08",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2022-11-02",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 3,
      "location_summary": "Irvine, California • Orange, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00544427"
    },
    {
      "nct_id": "NCT03209583",
      "title": "ATrial Tachycardia PAcing Therapy in Congenital Heart",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Arrhythmia",
        "Atrial Tachycardia",
        "Congenital Heart Disease",
        "Pacemaker Re-Entrant Tachycardia"
      ],
      "interventions": [
        {
          "name": "Medtronic",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ian Law",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 300,
      "start_date": "2018-09-01",
      "completion_date": "2027-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 14,
      "location_summary": "Los Angeles, California • Orange, California • Hollywood, Florida + 11 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03209583"
    },
    {
      "nct_id": "NCT05279664",
      "title": "RIC-NEC Randomized Controlled Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Remote ischemic conditioning (RIC) + Standard of Care for NEC",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care for NEC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Hospital for Sick Children",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "0 Weeks and older"
      },
      "enrollment_count": 78,
      "start_date": "2023-02-09",
      "completion_date": "2026-03-18",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-10-05T11:36:31.593Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05279664"
    }
  ]
}