{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?sponsor=Durect", "query": { "sponsor": "Durect" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 11, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?sponsor=Durect&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-17T12:47:34.401Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03432260", "title": "A Research Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DUR-928 in Patients With Alcoholic Hepatitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcoholic Hepatitis" ], "interventions": [ { "name": "DUR-928 30 mg", "type": "DRUG" }, { "name": "DUR-928 90 mg", "type": "DRUG" }, { "name": "DUR-928 150 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 19, "start_date": "2018-04-18", "completion_date": "2019-09-09", "has_results": true, "last_update_posted_date": "2024-09-24", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 7, "location_summary": "San Diego, California • Miami, Florida • Atlanta, Georgia + 4 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03432260" }, { "nct_id": "NCT00485225", "title": "Open Label, Safety Study of EN3270 in Patients With Moderate to Severe Non-malignant, Chronic Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic, Non Malignant Pain" ], "interventions": [ { "name": "EN3270", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 77, "start_date": "2007-06", "completion_date": "2008-07", "has_results": false, "last_update_posted_date": "2012-02-23", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 1, "location_summary": "Berlin, New Jersey", "locations": [ { "city": "Berlin", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00485225" }, { "nct_id": "NCT02574520", "title": "Trial of Extended Release Bupivacaine for Pain Relief After Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post Operative Pain" ], "interventions": [ { "name": "SABER-Bupivacaine (Part 1)", "type": "DRUG" }, { "name": "SABER-Bupivacaine (Part 2)", "type": "DRUG" }, { "name": "Saline Placebo", "type": "DRUG" }, { "name": "Bupivacaine HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 399, "start_date": "2015-11", "completion_date": "2017-08", "has_results": true, "last_update_posted_date": "2021-07-13", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 21, "location_summary": "Florence, Alabama • Sheffield, Alabama • Arcadia, California + 13 more", "locations": [ { "city": "Florence", "state": "Alabama" }, { "city": "Sheffield", "state": "Alabama" }, { "city": "Arcadia", "state": "California" }, { "city": "Fontana", "state": "California" }, { "city": "Laguna Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02574520" }, { "nct_id": "NCT04563026", "title": "A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcoholic Hepatitis" ], "interventions": [ { "name": "DUR-928 30 mg", "type": "DRUG" }, { "name": "DUR-928 90 mg", "type": "DRUG" }, { "name": "Placebo+ Standard of Care (SOC)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 307, "start_date": "2021-01-22", "completion_date": "2023-09-06", "has_results": false, "last_update_posted_date": "2024-09-05", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 48, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Coronado, California + 33 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Coronado", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04563026" }, { "nct_id": "NCT01096966", "title": "Study of the Efficacy and Safety of Bupivacaine TTS Patch in Patients With Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Low Back Pain" ], "interventions": [ { "name": "Bupivacaine TTS (Bupivacaine Patch)", "type": "DRUG" }, { "name": "Placebo patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 263, "start_date": "2010-03", "completion_date": "2011-02", "has_results": false, "last_update_posted_date": "2022-06-15", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 21, "location_summary": "Tempe, Arizona • La Mesa, California • Torrance, California + 18 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "La Mesa", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01096966" }, { "nct_id": "NCT07428538", "title": "Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hepatitis" ], "interventions": [ { "name": "Larsucosterol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch Health Americas, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 350, "start_date": "2026-01-29", "completion_date": "2028-02", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 86, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 62 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Coronado", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07428538" }, { "nct_id": "NCT01052012", "title": "Bupivacaine Effectiveness and Safety in SABER® Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Pain", "Abdominal Surgery" ], "interventions": [ { "name": "SABER-Bupivacaine", "type": "DRUG" }, { "name": "Bupivacaine HCl", "type": "DRUG" }, { "name": "SABER-Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 331, "start_date": "2009-12", "completion_date": "2011-09", "has_results": true, "last_update_posted_date": "2021-06-01", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 22, "location_summary": "Birmingham, Alabama • Florence, Alabama • Mobile, Alabama + 18 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Florence", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01052012" }, { "nct_id": "NCT00478179", "title": "Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postherpetic Neuralgia", "Pain" ], "interventions": [ { "name": "Transdermal/Patch (Bupivacaine TTS [Eladur™])", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 60, "start_date": "2006-09", "completion_date": "2007-12", "has_results": false, "last_update_posted_date": "2009-09-11", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 7, "location_summary": "La Jolla, California • Loma Linda, California • Santa Monica, California + 4 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Altoona", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00478179" }, { "nct_id": "NCT03837743", "title": "Safety and Efficacy Study of DUR-928 Topical Solution in Subjects With Plaque Psoriasis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Plaque Psoriasis" ], "interventions": [ { "name": "DUR-928 Topical Solution", "type": "DRUG" }, { "name": "Vehicle Topical Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 25, "start_date": "2019-02-21", "completion_date": "2020-05-20", "has_results": true, "last_update_posted_date": "2022-09-02", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 5, "location_summary": "San Diego, California • Miami, Florida • Tampa, Florida + 2 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "Plainfield", "state": "Indiana" }, { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT03837743" }, { "nct_id": "NCT04447404", "title": "DUR-928 in Subjects With SARS-CoV-2 With Acute Lung, Liver or Kidney Injury", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "SARS-CoV-2" ], "interventions": [ { "name": "DUR-928", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 2, "start_date": "2020-09-21", "completion_date": "2021-03-04", "has_results": true, "last_update_posted_date": "2022-08-05", "last_synced_at": "2026-09-17T12:47:34.401Z", "location_count": 1, "location_summary": "Newark, New Jersey", "locations": [ { "city": "Newark", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT04447404" } ] }