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Showing 25–37 of 13 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Acoustic Trauma Clear all
Not listed Phase 3 Interventional

A Comparison of the dermaPACE® (Pulsed Acoustic Cellular Expression) Device in Conjunction With Standard of Care Versus Standard of Care Alone in the Treatment of Diabetic Foot Ulcers

NCT01824407
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Electrohydraulic-generated shock wave, Sham device plus standard of care
Device
Lead sponsor
SANUWAVE, Inc.
Industry
Eligibility
22 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
18
States / cities
Phoenix, Arizona • Tucson, Arizona • Long Beach, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2014 · Synced Jul 22, 2026, 11:13 PM EDT
Enrolling by invitation Early Phase 1 Interventional

Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing Loss

NCT07472023
View directory record Official record
Conditions
Sensorineural Hearing Loss, Tinnitus, Acoustic Trauma, Inner Ear Injury, Noise-Induced Hearing Loss, Sudden Hearing Loss, Vestibular Dysfunction
Interventions
Audiologic Monitoring, Investigational Regenerative Pharmacologic Therapy, Stem Cell Regenerative Therapy, Combination Regenerative Therapy
Other · Drug · Biological + 1 more
Lead sponsor
Truway Health, Inc.
Industry
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2099
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 22, 2026, 11:13 PM EDT
Completed Phase 2 Interventional Results available

FX-322 in Adults With Acquired Sensorineural Hearing Loss

NCT05086276
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
26
States / cities
Tucson, Arizona • Fresno, California • Torrance, California + 23 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Jul 22, 2026, 11:13 PM EDT
Completed Phase 1 Interventional

FX-322 in Adults With Severe Sensorineural Hearing Loss

NCT04629664
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, Placebo
Drug · Other
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Novi, Michigan • Omaha, Nebraska • Amherst, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Jul 22, 2026, 11:13 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Protective Effects of EPI-743 on Noise-Induced Hearing Loss

NCT02257983
View directory record Official record
Conditions
Noise-induced Hearing Loss
Interventions
EPI-743, Placebo
Drug
Lead sponsor
Edison Pharmaceuticals Inc
Industry
Eligibility
18 Years to 30 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Jul 22, 2026, 11:13 PM EDT
Completed Not applicable Interventional Results available

HIRREM Developmental Study

NCT02709369
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes, Headache, Traumatic Brain Injury, Post Concussion Symptoms
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2019 · Synced Jul 22, 2026, 11:13 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)

NCT02903355
View directory record Official record
Conditions
Noise-induced Hearing Loss
Interventions
D-methionine, Placebo
Drug
Lead sponsor
Southern Illinois University
Other
Eligibility
21 Years to 45 Years
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Fort Jackson, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Jul 22, 2026, 11:13 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

NCT05883241
View directory record Official record
Conditions
Bone Fracture, Fresh Fracture
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, 2.5% Diclofenac Patches
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Trumbull, Connecticut • Lansdowne, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 22, 2026, 11:13 PM EDT
Completed No phase listed Observational

Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care

NCT05254470
View directory record Official record
Conditions
Musculoskeletal Injury, Pain, Chronic, Pain, Acute, Sport Injury, Soft Tissue Injuries, Arm Injury, Back Pain, Tendon Injuries, Muscle Injury
Interventions
Continuous Ultrasound
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fairfield, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Jul 22, 2026, 11:13 PM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Prevention of Noise-induced Hearing Loss

NCT02049073
View directory record Official record
Conditions
Noise-induced Hearing Loss
Interventions
Zonisamide, Methylprednisolone
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 22, 2026, 11:13 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Intervention for Hearing Health Among Native Americans

NCT07534098
View directory record Official record
Conditions
Noise-Induced Hearing Loss
Interventions
Talking Circle, Diabetes prevention program & delayed TC
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Tahlequah, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 22, 2026, 11:13 PM EDT
Completed Phase 1 Interventional

FX-322 in Adults With Age-Related Sensorineural Hearing Loss

NCT04601909
View directory record Official record
Conditions
Presbycusis, Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, placebo
Drug · Other
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
66 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Sarasota, Florida • Omaha, Nebraska • Amherst, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Jul 22, 2026, 11:13 PM EDT
Completed Phase 2 Interventional Results available

FX-322 in Adults With Stable Sensorineural Hearing Loss

NCT04120116
View directory record Official record
Conditions
Sensorineural Hearing Loss, Noise Induced Hearing Loss, Sudden Sensorineural Hearing Loss
Interventions
FX-322 (One Dose), FX-322 (Two Doses), FX-322 (Four Doses), Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
16
States / cities
Fresno, California • Torrance, California • Colorado Springs, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Jul 22, 2026, 11:13 PM EDT