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ClinicalTrials.gov public records Last synced May 22, 2026, 5:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Acute Otitis Media Clear all
Completed Phase 2 Interventional
View directory record Official record
Conditions
Pain, Acute Otitis Media
Interventions
Benzocaine, Placebo
Drug
Lead sponsor
Otic Therapy, LLC
Industry
Eligibility
2 Months to 12 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Clearwater, Florida • Gresham, Oregon • Murray, Utah
Source: ClinicalTrials.gov public record
Updated May 24, 2015 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Otitis Media, Serous, Negative Middle Ear Pressure, Rhinitis, Otitis Media With Effusion, Otitis Media, Secretory
Interventions
Triamcinolone acetonide nasal spray, Placebo nasal spray
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
6 Years to 100 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Acute Otitis Media
Interventions
amoxicillin-clavulanate, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
6 Months to 23 Months
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2016 · Synced May 22, 2026, 5:47 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Otitis Media Recurrent, Middle Ear Infection, Ear Infection
Interventions
Advanced Ultrasound Otoscope
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
0 Years to 12 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Acute Otitis Media, Otitis Media, Ear Infection
Interventions
Montelukast, Placebo
Drug
Lead sponsor
Deborah Gentile
Other
Eligibility
18 Months to 5 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Bellevue, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced May 22, 2026, 5:47 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Tympanostomy tube placement, Amoxicillin-Clavulanate and/or Ceftriaxone, Ofloxacin Otic
Device · Drug
Lead sponsor
Alejandro Hoberman
Other
Eligibility
6 Months to 35 Months
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2022 · Synced May 22, 2026, 5:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Otitis Media
Interventions
Iontophoresis System With Earset
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
12 Months and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
East Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Barotrauma;Ear, OME - Otitis Media With Effusion, AOM - Acute Otitis Media, Eustachian Tube Dysfunction
Interventions
Tymbion Iontophoresis and Tube Delivery System (TDS)
Combination Product
Lead sponsor
Tusker Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
8
States / cities
Roseville, California • San Jose, California • Louisville, Kentucky + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced May 22, 2026, 5:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
Interventions
Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group, Routine ENT Management (in-person and telehealth visits)- Control Group
Device · Other
Lead sponsor
Medentum Innovations
Industry
Eligibility
3 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tuscon, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced May 22, 2026, 5:47 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Ear Infection, Otitis Media
Interventions
Solo+ Tympanostomy Tube Device (Solo+ TTD)
Device
Lead sponsor
AventaMed DAC
Industry
Eligibility
6 Months to 13 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
7
States / cities
Alexander City, Alabama • Huntsville, Alabama • Opelika, Alabama + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced May 22, 2026, 5:47 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Tympanocentesis, Nasal Phalangeal Swab and Wash, Blood Draw
Procedure · Other
Lead sponsor
Rochester General Hospital
Other
Eligibility
6 Months to 36 Months
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced May 22, 2026, 5:47 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Otitis Media
Interventions
Tympanocentesis, Nose/throat swab, Observational
Procedure · Biological
Lead sponsor
Pfizer
Industry
Eligibility
6 Months to 30 Months
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
7
States / cities
Penfield, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 2Phase 3 Interventional Results available
View directory record Official record
Conditions
Otitis Media With Effusion, Acute Otitis Media
Interventions
tympanostomy tube
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
6 Months and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
4
States / cities
Port Saint Lucie, Florida • Louisville, Kentucky • San Antonio, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced May 22, 2026, 5:47 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Otitis Media, Urinary Tract Infection, Asthma, Head Injury
Interventions
patient-driven health IT product
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 12 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Boston, Massachusetts • Weymouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 5, 2007 · Synced May 22, 2026, 5:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Ciprofloxacin 0.3% and dexamethasone 0.1% otic suspension
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 4 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 1 Interventional Results available
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Drug: OP0201 20mg, Drug: Placebo 0mg
Combination Product
Lead sponsor
Novus Therapeutics, Inc
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Bellflower, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Otitis Media
Interventions
OTO-201 (ciprofloxacin)
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced May 22, 2026, 5:47 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Acute Otitis Media (AOM), Upper Respiratory Infection
Interventions
Standard Clinical Ear Exam, AI app ear exam and diagnosis
Diagnostic Test
Lead sponsor
Timothy Shope
Other
Eligibility
6 Months to 24 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced May 22, 2026, 5:47 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Acute Otitis Media, Pediatric Infectious Disease, Ear Infection
Interventions
High Intensity Intervention, Low Intensity Intervention
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
2 Years to 17 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced May 22, 2026, 5:47 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Otitis Media
Interventions
PE tube with Duckbill Valve
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced May 22, 2026, 5:47 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Otitis Media
Interventions
Intranasal fentanyl, morphine IM, IV morphine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Months to 6 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced May 22, 2026, 5:47 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Otitis Media With Effusion
Interventions
lansoprazole, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 12 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced May 22, 2026, 5:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Otitis Media
Interventions
Cranial osteopathic manipulative treatment., Echinacea purpurea, Sham osteopathic manipulative treatment, "Echinacea purpurea" placebo
Procedure · Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 60 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
3
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 2, 2008 · Synced May 22, 2026, 5:47 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Community Acquired Pneumonia (CAP), Sinusitis, Strep Pharyngitis, Acute Otitis Media (AOM)
Interventions
Online Educational Modules, Prescribing Feedback Reports, Clinical Decision Support, Live, hybrid in-person and online educational sessions
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Months to 12 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced May 22, 2026, 5:47 AM EDT