- Conditions
- Acute Respiratory Tract Infection, Otitis Media, Pharyngitis, Acute Sinusitis
- Interventions
- Broad Implementation of Outpatient Stewardship (BIOS) intervention
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 1,032 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 5
- States / cities
- Plantation, Florida • Cleveland, Ohio • Hershey, Pennsylvania + 1 more
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Showing 1–13
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- Conditions
- Acute Sore Throat
- Interventions
- Ear Acupuncture
- Device
- Lead sponsor
- Mike O'Callaghan Military Hospital
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Nellis Air Force Base, Nevada
- Conditions
- Acute Sinusitis, Streptococcal Pharyngitis, Pneumonia, Viral Infection
- Interventions
- Antimicrobial Stewardship Bundle
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- Not listed
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Interventions
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group, Routine ENT Management (in-person and telehealth visits)- Control Group
- Device · Other
- Lead sponsor
- Medentum Innovations
- Industry
- Eligibility
- 3 Years to 17 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Tuscon, Arizona
- Conditions
- Acute Pharyngitis, Sore Throat
- Interventions
- flurbiprofen, placebo
- Drug
- Lead sponsor
- Reckitt Benckiser LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 122 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Storrs, Connecticut
- Conditions
- Acute Sore Throat
- Interventions
- Standard treatment plus ear acupuncture
- Device
- Lead sponsor
- Mike O'Callaghan Military Hospital
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Nellis Air Force Base, Nevada
- Conditions
- Acute Otitis Media, Acute Sinusitis, Group A Streptococcal Pharyngitis
- Interventions
- Broad-spectrum antibiotics, Narrow-spectrum antibiotics
- Drug
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 2,472 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis
- Interventions
- Quasi experimental intervention
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- Not listed
- Enrollment
- 26,139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 2
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Acute Otitis Media, Allergic Rhinitis, Sinusitis, Constipation, Pharyngitis, Croup, Urticaria, Bronchiolitis
- Interventions
- Electronic point-of-care delivery system
- Device
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 0 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1999 – 2003
- U.S. locations
- 2
- States / cities
- Seattle, Washington • Skagit Valley, Washington
- Conditions
- Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute, Septic Arthritis, Orbital Cellulitis, Facial Cellulitis, Mastoiditis, Cervical Adenitis, Retropharyngeal Abscess, Peritonsillar Abscess
- Interventions
- Trimethoprim Sulfamethoxazole
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 2 Months to 18 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder, Surgery
- Interventions
- Ketorolac, Dexmedetomidine, Morphine, Fentanyl
- Drug
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 2 Years to 18 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Philadelphia, Pennsylvania • Memphis, Tennessee
- Conditions
- Pharyngitis
- Interventions
- celecoxib, placebo
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 18 Years to 18 Years
- Enrollment
- 269 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Storrs, Connecticut
- Conditions
- Community Acquired Pneumonia (CAP), Sinusitis, Strep Pharyngitis, Acute Otitis Media (AOM)
- Interventions
- Online Educational Modules, Prescribing Feedback Reports, Clinical Decision Support, Live, hybrid in-person and online educational sessions
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 420 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania