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Showing 1–24 of 118 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol; Use, Problem; Alcohol Use Disorder Clear all
Completed No phase listed Observational Results available

STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse

NCT00369746
View directory record Official record
Conditions
Major Depressive Disorder, Alcohol Use Disorder
Interventions
citalopram
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional

AABM to Decrease Problem Drinking and Impulsivity in Veterans With AUD: A Pilot Study

NCT02600832
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
AABM Training, Sham Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Phase 1 Interventional

Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol

NCT03548714
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Interaction
Interventions
PT150, Beverage
Drug · Other
Lead sponsor
Pop Test Oncology LLC
Industry
Eligibility
21 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders

NCT02322047
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder (PTSD)
Interventions
Prazosin, Naltrexone, Placebo (Prazosin), Placebo (Naltrexone)
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 28, 2020 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional

Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological Treatment for Alcohol Use Disorder

NCT03842670
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse, Alcohol Drinking, Alcohol Dependence
Interventions
Cognitive Behavior Therapy, Mindfulness Based Relapse Prevention
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
22 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional

Evaluating a One-Year Version of the Parent-Child Assistance Program

NCT06163651
View directory record Official record
Conditions
Alcohol Use Disorder, Substance Use Disorders, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use Disorders, Drug Use Complicating Pregnancy, Unspecified Trimester
Interventions
Parent-Child Assistance Program - One-Year Version
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Enid, Oklahoma • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional

Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault

NCT06444295
View directory record Official record
Conditions
Posttraumatic Stress Symptom, Alcohol Drinking, Alcohol Problem
Interventions
Activity scheduling, Cognitive restructuring, Coaching calls, Non-core intervention components
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Phase 4 Interventional

Improving Hepatitis C Treatment in Injection Drug Users

NCT00148031
View directory record Official record
Conditions
Hepatitis C, Liver Diseases, Drug Abuse, Alcoholism
Interventions
Pegylated Interferon and Ribavirin, Psychosocial, On-site (MMT Clinic) HCV evaluation and treatment, Off-site HCV evaluation and treatment
Drug · Behavioral
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 65 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
2
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reactions to E-cigs and Alcohol

NCT03449017
View directory record Official record
Conditions
Alcohol Abuse, Nicotine Dependence Tobacco Product
Interventions
E-cig use
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Jul 23, 2026, 6:19 AM EDT
Completed No phase listed Observational

Novel Real-world Methods in Social Drinkers and AUD

NCT05155176
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
Interventions
Intensive Day Monitoring
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Phase 2 Interventional

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
Interventions
Psilocybin, Ketamine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Phase 4 Interventional Results available

Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy

NCT01087736
View directory record Official record
Conditions
PTSD, Alcohol Abuse, Alcoholism
Interventions
Topiramate, Placebo administration
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Jul 23, 2026, 6:19 AM EDT
Not listed Not applicable Interventional

Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD

NCT01663337
View directory record Official record
Conditions
PTSD, Alcohol Abuse, Alcohol Dependence
Interventions
Cognitive Processing Therapy (CPT), Relapse Prevention (RP)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of Mindfulness-based Resilience Training for Rural Law Enforcement Officers

NCT05629637
View directory record Official record
Conditions
Problem Drinking, Aggression, Stress, Psychological
Interventions
Mindfulness-Based Resilience Training (MBRT)
Behavioral
Lead sponsor
Pacific University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Forest Grove, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)

NCT07216872
View directory record Official record
Conditions
Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Alcohol Dependence, Alcohol Abuse/Dependence, Alcohol Addiction
Interventions
Deep TMS (DTMS), Sham (No Treatment)
Device
Lead sponsor
Brainsway
Industry
Eligibility
18 Years to 86 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
Tuscaloosa, Alabama • La Jolla, California • West Palm Beach, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Care for Unhealthy Alcohol Use in Primary Care

NCT04565899
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder
Interventions
Practice facilitation implementation intervention
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

NCT05619185
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Relations, Interpersonal, Military Family
Interventions
CRAFT Web-Based Intervention, Phone-Based CRAFT, CRAFT Workbook, Gottman Self-Guided Resources
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
744 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Phase 2 Interventional

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

NCT04084860
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
CI-581a, CI-581b, MBRP, MET
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional

Phased Treatment for Social Anxiety Disorder and Coping Behaviors in a Medical Setting

NCT00862212
View directory record Official record
Conditions
Social Anxiety Disorder, Alcohol Use Disorders
Interventions
Brief Alcohol Intervention
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Minneapolis, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2013 · Synced Jul 23, 2026, 6:19 AM EDT
Withdrawn Phase 1 Interventional

Trial of Computerized MET for Adolescent Substance Use

NCT01784653
View directory record Official record
Conditions
Drug Abuse, Alcohol Abuse, Nicotine Dependence
Interventions
iMET, MET
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Psychodynamic Therapy For Co-occurring Borderline Personality Disorder and Alcohol Use Disorder

NCT00145678
View directory record Official record
Conditions
Borderline Personality Disorder, Alcohol Use Disorder
Interventions
Psychodynamic Therapy, Optimized Community Care
Behavioral
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 5, 2015 · Synced Jul 23, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid Use

NCT05325788
View directory record Official record
Conditions
Alcohol Use Disorder, Opioid Use Disorder
Interventions
e-Covery, Comparator Condition
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Jul 23, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking

NCT06501677
View directory record Official record
Conditions
Alcohol; Use, Problem
Interventions
WBI
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 23, 2026, 6:19 AM EDT
Withdrawn Phase 1Phase 2 Interventional

cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use

NCT01275391
View directory record Official record
Conditions
Tobacco Abuse, Alcohol Abuse, Drug Abuse
Interventions
Computer Screening, Brief Intervention, Referral toTreatment
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Jul 23, 2026, 6:19 AM EDT