- Conditions
- Amputation, Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation at Ankle (Injury), Lower Limb Amputation Knee, Lower Limb Amputation at Hip (Injury)
- Interventions
- Flat terrain locomotor training, Uneven terrain locomotor training
- Other
- Lead sponsor
- University of Nevada, Las Vegas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 96
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Unilateral Traumatic Amputation, Amputation, Traumatic
- Interventions
- Powered ankle prosthesis, Dynamic Response Foot
- Device
- Lead sponsor
- Deanna H Gates
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
- Interventions
- ACTIVE cryoneurolysis, SHAM cryoneurolysis
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Cerebrovascular Disorders, Healthy, Nervous System Diseases, Spinal Cord Injuries
- Interventions
- Not listed
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- Not listed
- Enrollment
- 175 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1986 – 2001
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Severe Distal Tibia Injury, Severe Ankle Injury, Severe Foot Injury, Major Soft Tissue Loss, Major Bone Articular Surface Loss, Major Ankle Articular Surface Loss
- Interventions
- Not listed
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 664 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2019
- U.S. locations
- 33
- States / cities
- Birmingham, Alabama • San Diego, California • San Francisco, California + 26 more
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User, Upper Limb Amputation Below Elbow (Injury), Amputation; Traumatic, Arm: Forearm, Between Elbow and Wrist
- Interventions
- Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active, Experimental socket with 8 targeted channels active, Coapt EMG Cuff
- Device
- Lead sponsor
- Liberating Technologies, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Holliston, Massachusetts
- Conditions
- Symptomatic Neuroma, Amputation, Chronic Nerve Pain
- Interventions
- Axoguard Nerve Cap®
- Device
- Lead sponsor
- Axogen Corporation
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Lubbock, Texas
- Conditions
- Stroke, Parkinson Disease, Lower Limb Amputation Knee, Fall Injury, Fall Patients, Falling
- Interventions
- Airbag Belt Fall Protection System
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Wounds, Wounds and Injuries, Extremity Injury, Traumatic Wounds and Injuries, Amputation, Traumatic/Surgery, Amputation, Wound, Open Fracture Wounds
- Interventions
- Clinical Decision Support Tool, Standard of Care (SOC)
- Device · Procedure
- Lead sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 5
- States / cities
- Birmingham, Alabama • Atlanta, Georgia • Indianapolis, Indiana + 2 more
- Conditions
- Amputation, Fracture, Inflammation, Osteoporosis
- Interventions
- Amputation rehabilitation exercise program, Osteomyoplasty vs. routine long posterior flap
- Behavioral · Procedure
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 95 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Not listed
- Lead sponsor
- Boise VA Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Boise, Idaho
- Conditions
- Tetraplegia, Spinal Cord Injury, Brainstem Stroke, Brachial Plexus Injury, Above Elbow Amputation
- Interventions
- Implantation of CRS Arrays
- Device
- Lead sponsor
- Michael Boninger
- Other
- Eligibility
- 22 Years to 70 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2029
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Pittsburgh, Pennsylvania
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Surgical, Upper Limb Amputation Above Elbow (Injury)
- Interventions
- eOPRA, OPRA, eOPRA with sensory feedback, eOPRA without sensory feedback
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Amputation, Traumatic
- Interventions
- IMES
- Device
- Lead sponsor
- The Alfred E. Mann Foundation for Scientific Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
- Interventions
- Ottobock CLeg4 + Ottobock foot, SRALAB Hybrid Knee + Polycentric Ankle, SRALAB Hybrid Knee + Passive Ankle, Ottobock CLeg 4 + Polycentric Ankle
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Traumatic Amputation
- Interventions
- NMES (EMPI 300PV stimulator) plus standard of care, TMARP standard of care
- Device · Behavioral
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 3
- States / cities
- San Diego, California • Bethesda, Maryland • Memphis, Tennessee
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
- Interventions
- Ossur Power Knee, Reboocon Intuy Knee
- Device
- Lead sponsor
- Liberating Technologies, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Knee
- Interventions
- Revo-M, Taleo, Proflex XC
- Device
- Lead sponsor
- Otto Bock Healthcare Products GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 4
- States / cities
- Mesa, Arizona • Linthicum, Maryland • Dayton, Ohio + 1 more
- Conditions
- Diabetic Foot Ulcer Outcome, Quality of Patient Care
- Interventions
- cellular and tissue based therapy, negative pressure wound therapy, debridement, advanced wound therapy, Nutritional screening, off-loading, Hyperbaric oxygen Therapy
- Biological · Device · Procedure + 1 more
- Lead sponsor
- U.S. Wound Registry
- Other
- Eligibility
- Not listed
- Enrollment
- 10,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 1
- States / cities
- The Woodlands, Texas
- Conditions
- Limb Injury
- Interventions
- Not listed
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 4
- States / cities
- San Diego, California • Bethesda, Maryland • Rochester, Minnesota + 1 more
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Below Knee (Injury)
- Interventions
- ICE Condition, Sham Condition
- Device
- Lead sponsor
- Liberating Technologies, Inc.
- Industry
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 2
- States / cities
- Holliston, Massachusetts • Minneapolis, Minnesota
- Conditions
- Amputation Wound, Peripheral Arterial Disease
- Interventions
- SpectralMD DeepView Wound Imaging System 2.0
- Device
- Lead sponsor
- SpectralMD
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
- Interventions
- Usual care
- Other
- Lead sponsor
- U.S. Wound Registry
- Other
- Eligibility
- Not listed
- Enrollment
- 300,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2030
- U.S. locations
- 1
- States / cities
- The Woodlands, Texas
- Conditions
- Diabetes Mellitus, Leg Injuries, Traumatic Amputation
- Interventions
- Transverse plane rotation adaptor pylon, Rigid pylon
- Device
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- Seattle, Washington