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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Amputation; Traumatic, Hand Clear all
Not yet recruiting Not applicable Interventional

To Evaluate the Clinical Impact of the Point Powered System

NCT07135947
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Point Powered partial hand prosthetic system
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Aurora, Colorado • Broomfield, Colorado • Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dexterous Partial Hand Prosthesis Outcomes

NCT05038566
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper, Prosthesis User, Upper Limb Amputation at the Hand
Interventions
Pointdexter
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
Not listed
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Holliston, Massachusetts • Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional

Functional Importance of a Powered Multifunction Wrist Protocol

NCT04069793
View directory record Official record
Conditions
Upper Limb Amputation at the Hand, Upper Limb Amputation at the Wrist, Amputation, Amputation; Traumatic, Limb
Interventions
Commercially available device, Non FDA registered device
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional Results available

To Assess the Utility of the Point Digit in a Clinical Take-home Study

NCT04755790
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Point Digit
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
7
States / cities
Lafayette, Colorado • Overland Park, Kansas • Maple Grove, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 21, 2026, 9:07 PM EDT
Recruiting No phase listed Observational

Human Upper Extremity Allotransplantation: F/U Protocol

NCT03400345
View directory record Official record
Conditions
Amputation, Traumatic, Wounds and Injury, Hand Injuries
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional

Assessing Force Feedback With the SoftHand Pro

NCT03412656
View directory record Official record
Conditions
Amputation, Traumatic, Limb Defect
Interventions
SoftHand Pro with CUFF force feedback device
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional

Vascularized Composite Allotransplantation of the Hand and Upper Extremity (Hand Transplant)

NCT02165865
View directory record Official record
Conditions
Traumatic Amputation of Arm, Traumatic Amputation of Hand
Interventions
upper extremity/ hand transplantation
Procedure
Lead sponsor
Southern Illinois University
Other
Eligibility
18 Years to 69 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Jul 21, 2026, 9:07 PM EDT
Recruiting Not applicable Interventional

DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)

NCT02994160
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Fast electrode
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Recruiting Not applicable Interventional

Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation

NCT05768802
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Hand
Interventions
Myoelectric Implantable Recording Array (MIRA)
Device
Lead sponsor
Boninger, Michael, MD
Other
Eligibility
22 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Not listed Not applicable Interventional

Application of Targeted Reinnervation for People With Transradial Amputation

NCT02349035
View directory record Official record
Conditions
Amputation; Traumatic, Hand, and Wrist, Amputation; Traumatic, Hand, at Wrist Level
Interventions
Compare control of multifunction transradial prosthesis, Perform TMR surgery and evaluate transradial TMR pattern recognition control of multifunctional prostheses.
Device · Procedure
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
3
States / cities
Chicago, Illinois • Bethesda, Maryland • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Jul 21, 2026, 9:07 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices

NCT06420687
View directory record Official record
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
Interventions
Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF, Experimental prosthesis - Wrist rotation + Multi DOF hand, Experimental prosthesis - Wrist rotation + wrist flexion + Multi DOF hand
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Jul 21, 2026, 9:07 PM EDT
Withdrawn No phase listed Observational

A Comparison of the Outcomes of Distal Fingertip Amputations Treated With Either Artificial (Xeroform) or Biological Dressings

NCT03968835
View directory record Official record
Conditions
Finger Injuries, Amputation, Traumatic
Interventions
Bacitracin, Skin Graft
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
Up to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Jul 21, 2026, 9:07 PM EDT
Recruiting Not applicable Interventional

To Assess the Utility of the Point Mini in a Clinical Take-home Study

NCT06501092
View directory record Official record
Conditions
Amputation; Traumatic, Hand, Amputation, Congenital
Interventions
Point Mini
Device
Lead sponsor
Point Designs
Industry
Eligibility
3 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Lafayette, Colorado • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional Results available

Validation of Point Partial User Needs With Partial Finger Amputees

NCT05012657
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Point Partial
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Aurora, Colorado • Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Jul 21, 2026, 9:07 PM EDT
Withdrawn No phase listed Observational

Hand Transplantation: Functional and Quality of Life Outcomes

NCT02331355
View directory record Official record
Conditions
Amputation; Traumatic, Arm, Upper, Between Shoulder and Elbow, Amputation; Traumatic, Hand, Amputation; Traumatic, Hand, Both, Amputation; Traumatic, Arm: Forearm, at Elbow Level, Amputation; Traumatic, Arm, Upper
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 15, 2020 · Synced Jul 21, 2026, 9:07 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Human Upper Extremity (Hand and Forearm) Allotransplantation

NCT00722280
View directory record Official record
Conditions
Amputation, Traumatic
Interventions
Hand Transplantation
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

EMG-Based Hand-Wrist Control: Study B Mirrored

NCT04692571
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Hand, Amputation, Congenital, Prosthesis User
Interventions
PSICON Measurement Apparatus
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Holliston, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional Results available

To Assess the Utility of the Point Partial in a Clinical Take-home Study of Partial Hand Amputees

NCT05012683
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Point Partial
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
7
States / cities
Lafayette, Colorado • Overland Park, Kansas • Maple Grove, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jul 21, 2026, 9:07 PM EDT
Withdrawn Not applicable Interventional

To Validate Point Mini User Needs

NCT06504667
View directory record Official record
Conditions
Amputation; Traumatic, Hand, Amputation, Congenital
Interventions
Point Mini
Device
Lead sponsor
Point Designs
Industry
Eligibility
5 Years to 15 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Aurora, Colorado • Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Recruiting Phase 2 Interventional

Human Upper Extremity Allotransplantation

NCT01459107
View directory record Official record
Conditions
Amputation, Traumatic, Wounds and Injuries, Hand Injuries
Interventions
Deceased donor hand transplantation, Bone marrow cell-based therapy & single-drug immunosuppression.
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 69 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2036
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 21, 2026, 9:07 PM EDT
Completed Not applicable Interventional Results available

Validation of User Needs of the Point Digit With Partial Hand Amputees

NCT04763278
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Point Digit
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Aurora, Colorado • Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Jul 21, 2026, 9:07 PM EDT