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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
Interventions
ACTIVE cryoneurolysis, SHAM cryoneurolysis
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
La Jolla, California
Conditions
Transtibial Amputation, Peripheral Artery Disease, Diabetes Mellitus
Interventions
Error-augmentation gait training, Error-correction gait training, Supervised walking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Aurora, Colorado • Richmond, Virginia
Completed No phase listed Observational Accepts healthy volunteers

Virtual Integrated Environment in Decreasing Phantom Limb Pain

NCT01462461
Conditions
Phantom Limb
Interventions
Not listed
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Results available

Home Study of an Advanced Upper Limb Prosthesis

NCT01551420
Conditions
Traumatic Amputation of Arm
Interventions
Advanced upper limb prosthetic device IMU controlled, Advanced upper limb prosthetic EMG-PR controlled
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
4
States / cities
Tampa, Florida • New York, New York • Providence, Rhode Island + 1 more
Conditions
Amputation, Amputation of Lower Limb, Amputation of Upper Limb, Amputation, Limb Loss, Amputation, Traumatic/Surgery, Cryo Analgesia
Interventions
cryoablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
6
States / cities
Pittsfield, Massachusetts • Manchester, New Hampshire • New York, New York + 3 more
Conditions
Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User, Upper Limb Amputation Below Elbow (Injury), Amputation; Traumatic, Arm: Forearm, Between Elbow and Wrist
Interventions
Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active, Experimental socket with 8 targeted channels active, Coapt EMG Cuff
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Holliston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers Results available

Longitudinal Study of Weight Change Following Lower Limb Amputation

NCT00932399
Conditions
Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
27 Years to 89 Years · Male only
Enrollment
4,549 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Not yet recruiting Not applicable Interventional

Neuromusculoskeletal Interface for Bionic Arms

NCT07032753
Conditions
Amputation, Amputation, Traumatic, Amputation, Surgical, Upper Limb Amputation Above Elbow (Injury)
Interventions
eOPRA, OPRA, eOPRA with sensory feedback, eOPRA without sensory feedback
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Not listed
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
10
States / cities
San Francisco, California • Tampa, Florida • Baltimore, Maryland + 7 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

What is the Optimal Stiffness and Height of a Running-specific Prosthesis?

NCT02318979
Conditions
Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
Interventions
Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
Device
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boulder, Colorado
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Treadmill Training
Other
Lead sponsor
Stony Brook University
Other
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis
Device
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Boulder, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Development of a Simulation Tool for Upper Extremity Prostheses

NCT01622530
Conditions
Traumatic Amputation of Upper Limb, Level Unspecified
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
Interventions
Ottobock CLeg4 + Ottobock foot, SRALAB Hybrid Knee + Polycentric Ankle, SRALAB Hybrid Knee + Passive Ankle, Ottobock CLeg 4 + Polycentric Ankle
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

No Power Bionic Lower Extremity Prosthesis

NCT04070105
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Leg, Lower
Interventions
Compliant Adaptive Energy Storage and Return Foot, AllPro
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Active, not recruiting No phase listed Observational

Kinematics of Ewing Amputees

NCT06371209
Conditions
Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation, Agonist-Antagonist Myoneural Interface
Interventions
Modified Amputation, Standard Amputation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic
Interventions
Low cost lower limb prosthetic socket
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Amputation, Traumatic, Wounds and Injuries, Hand Injuries
Interventions
Deceased donor hand transplantation, Bone marrow cell-based therapy & single-drug immunosuppression.
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 69 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2036
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vacuum Suspension: Effects on Tissue Oxygenation, Activity and Fit

NCT00117793
Conditions
Amputation, Diabetes, Leg Injuries, Traumatic Amputations
Interventions
Total Surface Bearing Suction Socket, Vacuum assisted socket system
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of External Mechanical Work Between Different Prosthetic Feet

NCT01340807
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Specialized Functional Prosthetic Training
Other
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
40 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prosthetic Components and Stability in Amputee Gait

NCT00167778
Conditions
Diabetes Mellitus, Leg Injuries, Traumatic Amputation
Interventions
Transverse plane rotation adaptor pylon, Rigid pylon
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Amputation, Traumatic, Wounds and Injury, Hand Injuries
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Amputation, Traumatic
Interventions
IMES
Device
Lead sponsor
The Alfred E. Mann Foundation for Scientific Research
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland