- Conditions
- Muscle Atrophy, Muscle Weakness, Fractures
- Interventions
- Physical Therapy
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1995 – 2000
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
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Showing 1–24
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- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder, Osteoarthritis Ankle, Elbow Osteoarthritis, Epicondylitis of the Elbow, Plantar Fasciitis of Both Feet, Tendinopathy
- Interventions
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Biological · Device
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2035
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Knee Pain, Hip Pain, Ankle Pain, Lumbopelvic Pain
- Interventions
- lumbosacral joint manipulation, lumbar passive range of motion, No active intervention
- Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Pain, Ankle Sprain
- Interventions
- PENNSAID, Diclofenac hydroxyethylpyrrolidine
- Drug
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Ankle Sprains, Ankle Injuries and Disorders
- Interventions
- Walking, Rucking, Running
- Other
- Lead sponsor
- Danielle Torp
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky • Charlotte, North Carolina
- Conditions
- Pain
- Interventions
- Clonidine, ropivacaine
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Sprain, Strain
- Interventions
- Ketoprofen Topical Patch 20%
- Drug
- Lead sponsor
- APR Applied Pharma Research s.a.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Spinal Cord Injury
- Interventions
- C-Brace II, Traditional Care KAFO intervention
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
- Interventions
- Not listed
- Lead sponsor
- Jose Soberon, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Pain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid Dependence, Opioid Analgesia
- Interventions
- Buprenorphine Transdermal System, Placebo Patch
- Drug
- Lead sponsor
- Jenna-Leigh Wilson
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Ankle Sprain
- Interventions
- Mobilization therapy in addition to standard therapy, Sham intervention
- Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Chronic Tendinopathy
- Interventions
- PNT + PRP, PNT alone
- Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2019
- U.S. locations
- 2
- States / cities
- New York, New York
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury, Fusion of Joint
- Interventions
- Foot and Ankle Devices
- Device
- Lead sponsor
- Stryker Trauma and Extremities
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 119 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Hamilton, New Jersey • Charlotte, North Carolina
- Conditions
- Bunion of Unspecified Foot, Bunionette of Unspecified Foot, Hammertoe, Ankle Fractures, Achilles Tendon Surgery
- Interventions
- Acetominophen, Toradol, Meloxicam, Cyclobenzaprine, Lyrica
- Drug
- Lead sponsor
- Prisma Health-Midlands
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Injury
- Interventions
- Narrative, Control
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2013
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Plantar Fasciosis, Achilles Tendinosis
- Interventions
- TOPAZ MicroDebrider
- Device
- Lead sponsor
- ArthroCare Corporation
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2007
- U.S. locations
- 3
- States / cities
- Mesa, Arizona • Santa Monica, California • Oakwood, Georgia
- Conditions
- Ankle and Hindfoot Arthrodesis
- Interventions
- AUGMENT® Bone Graft, Standard of Care
- Device · Procedure
- Lead sponsor
- BioMimetic Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 21
- States / cities
- Tucson, Arizona • Capitola, California • San Francisco, California + 18 more
- Conditions
- Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
- Interventions
- EA-KAFO
- Device
- Lead sponsor
- National Institutes of Health Clinical Center (CC)
- NIH
- Eligibility
- 5 Years to 100 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
- Interventions
- Exparel, Peripheral Nerve Block
- Drug
- Lead sponsor
- St. Luke's Hospital, Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Bethlehem, Pennsylvania
- Conditions
- Ankle Injuries, Foot Injuries and Disorders, Body Weight Changes
- Interventions
- Nutrition and Exercise Instruction
- Behavioral
- Lead sponsor
- Nell Blake, DPM
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Post-Traumatic Osteoarthritis of Ankle, Ankle Osteoarthritis, Ankle Injuries
- Interventions
- Osteochondral allograft ankle
- Procedure
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Ankle Injuries, Sprains and Strains, Joint Instability
- Interventions
- Hyperarch Fascia Training
- Behavioral
- Lead sponsor
- Applied Science & Performance Institute
- Industry
- Eligibility
- 20 Years to 45 Years
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Ankle Fracture
- Interventions
- Ultrasound
- Other
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 2 Years to 18 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures, Ankle Fractures, Tibial Fractures
- Interventions
- Decision tool, Standard treatment information
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 2,310 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2027
- U.S. locations
- 1
- States / cities
- Durham, North Carolina