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ClinicalTrials.gov public records Last synced May 22, 2026, 5:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Ankle Pain Clear all
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Ankle
Interventions
Group Physical Therapy Classes
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced May 22, 2026, 5:46 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Plantar Fasciitis of Both Feet, Metatarsalgia, Morton Neuroma, Hallux Valgus Deformity, Low Back Pain, Knee Pain, Ankle Pain
Interventions
Arch supports
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced May 22, 2026, 5:46 AM EDT
Completed Phase 4 Interventional
View directory record Official record
Conditions
Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
Interventions
Exparel, Peripheral Nerve Block
Drug
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced May 22, 2026, 5:46 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Pain, Ankle Injuries
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced May 22, 2026, 5:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Ankle Injuries, Sprains and Strains, Joint Instability
Interventions
Hyperarch Fascia Training
Behavioral
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
20 Years to 45 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced May 22, 2026, 5:46 AM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Narcotic Consumption, Pain, Wound Healing, Patient Satisfaction
Interventions
Iceman® Cold Therapy unit (djOrtho), Ice
Device · Other
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced May 22, 2026, 5:46 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Acute Pain, Ankle Sprain
Interventions
Diclofenac Sodium, Matching Placebo Patch
Drug
Lead sponsor
Cerimon Pharmaceuticals
Industry
Eligibility
17 Years to 75 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2010 · Synced May 22, 2026, 5:46 AM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
clinical examination, MRI
Diagnostic Test · Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced May 22, 2026, 5:46 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Ankle Sprain
Interventions
Ketoprofen Patch, Placebo Patch
Drug · Other
Lead sponsor
Hisamitsu Pharmaceutical Co., Inc.
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
25
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced May 22, 2026, 5:46 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Ankle Surgery
Interventions
Nerve block
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced May 22, 2026, 5:46 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Osteoarthritis, Osteo Arthritis Knee, Osteo Arthritis Shoulders, Osteoarthritis of Multiple Joints, Osteoarthritis, Hip, Osteoarthritis - Ankle/Foot
Interventions
Tissue Stromal Vascular Fraction (tSVF) Arm 1, PRP Concentrate Arm 1, Tissue Stromal Vascular Fraction (tSVF) Arm 2, PRP Concentrate Arm 2, Cellular Stromal Vascular Fraction (cSVF) Arm 2, Cellular Stromal Vascular Fraction (cSVF) Arm 3, Sterile Normal Saline (IV Solution)
Procedure · Biological · Drug
Lead sponsor
Healeon Medical Inc
Industry
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
2
States / cities
Valencia, California • Stevensville, Montana
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced May 22, 2026, 5:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Ankle Osteoarthritis
Interventions
iovera
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced May 22, 2026, 5:46 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
Interventions
AURYON Atherectomy System
Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
10
States / cities
Scottsdale, Arizona • Tucson, Arizona • Davenport, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced May 22, 2026, 5:46 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Pain, Postoperative, Fracture, Ankle, Pilon Fracture of Tibia, Foot Fracture
Interventions
Auricular acupuncture
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced May 22, 2026, 5:46 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
Interventions
ropivacaine 0.2%
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2019 · Synced May 22, 2026, 5:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Rotator Cuff Repair, Ankle Arthroplasty or Arthrodesis, Hallux Valgus (Bunion) Resection
Interventions
Peripheral Nerve Stimulation, Sham
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Los Angeles, California • San Diego, California • Bethesda, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced May 22, 2026, 5:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Patellofemoral Pain
Interventions
Mobilization with Movement, No mobilization with movement and education
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 59 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced May 22, 2026, 5:46 AM EDT
Terminated Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Ankle Sprain
Interventions
diclofenac sodium, Matching placebo patch
Drug
Lead sponsor
Cerimon Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2008 · Synced May 22, 2026, 5:46 AM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Ankle Fracture
Interventions
Tourniquet, No Tourniquet
Device · Other
Lead sponsor
Alex Demers
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced May 22, 2026, 5:46 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle, Hip, Elbow, Neurological, Vestibular, Pelvic Floor, TMJ, Fibromyalgia, Headaches, Lymphedema
Interventions
Not listed
Lead sponsor
ATI Holdings, LLC
Industry
Eligibility
Not listed
Enrollment
4,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced May 22, 2026, 5:46 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Ankle Arthritis, Ankle Arthropathy
Interventions
Intra-articular injection, Peripheral nerve block
Procedure
Lead sponsor
Slocum Research & Education Foundation
Other
Eligibility
40 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced May 22, 2026, 5:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Ankle Fracture
Interventions
Exparel
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 22, 2016 · Synced May 22, 2026, 5:46 AM EDT
Terminated Phase 3 Interventional
View directory record Official record
Conditions
Acute Pain From Ankle Sprain or Strain
Interventions
K-103-IP, Placebo
Drug
Lead sponsor
Kowa Research Institute, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
47
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tempe, Arizona + 44 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced May 22, 2026, 5:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Injuries, Injury Arm, Injury;Sports, Injury, Knee, Injury Wrist, Injury, Ankle, Injury Foot, Injury, Hand, Injury Finger, Injury Leg
Interventions
RelieveVRx
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced May 22, 2026, 5:46 AM EDT