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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Pre-Emptive Analgesia in Ano-Rectal Surgery

NCT02402543
View directory record Official record
Conditions
Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
Interventions
Gabapentin, Ketamine, Acetaminophen, Dexamethasone, Placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Burlington, Vermont • Colchester, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 15, 2018 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parkinson's Disease and Digestive Health

NCT04032262
View directory record Official record
Conditions
Parkinson Disease, Constipation, Gastro-Intestinal Disorder
Interventions
Gastrointestinal and Parkinson's Disease
Diagnostic Test
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated Not applicable Interventional

An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy

NCT01595412
View directory record Official record
Conditions
Rectal Prolapse, Procidentia
Interventions
Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
6
States / cities
Orlando, Florida • Tampa, Florida • Weston, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Vaginal Dilator Therapy After Pelvic Radiation

NCT07216456
View directory record Official record
Conditions
Pelvic Radiotherapy, Vaginal Stenosis, Pelvic Cancer, Gynecologic Cancers, Anorectal Cancer, Urologic Cancer
Interventions
Improving Engagement with Vaginal Dilator Therapy after Pelvic Radiation
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Trial to Evaluate Fecobionics in Fecal Incontinence (FI) (NORMAL and ABNORMAL-FI)

NCT05412069
View directory record Official record
Conditions
Normal Subjects, Fecal Incontinence
Interventions
Fecobionics
Device
Lead sponsor
The California Medical Innovations Institute, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
San Diego, California • Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated Not applicable Interventional

A Multimodal Enhanced Recovery Program in Anorectal Surgery

NCT03992079
View directory record Official record
Conditions
Colorectal Disorders, Anorectal Disorder, Patient Satisfaction, Pain, Postoperative, Opioid Use, Opioid Abuse, Opioid Dependence
Interventions
ReCOVER Enhanced Recovery Protocol
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting No phase listed Observational

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

NCT06315179
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Indeterminate Colitis, Functional Abdominal Pain Syndrome, Functional Bowel Disorder, Esophageal Diseases, Gastroduodenal Disorder, Bowel Dysfunction, Gallbladder Diseases, Sphincter of Oddi Dysfunction, Anorectal Disorder
Interventions
Esophagogastroduodenoscopy (EGD) with biopsy, Colonoscopy w/ biopsy
Diagnostic Test
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Years to 21 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

At-Home Genital Nerve Stimulation for SCI Bowel

NCT06836739
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Genital nerve stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Post Hemorrhoidectomy Anorectal Pain

NCT03240185
View directory record Official record
Conditions
Hemorrhoid Pain
Interventions
deep breathing exercises
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated Phase 4 Interventional

Comparison of Esophageal and Anorectal Manometry Catheters

NCT00204763
View directory record Official record
Conditions
Achalasia, Nutcracker Esophagus, Scleroderma, Esophageal Spasm, Fecal Incontinence
Interventions
Air filled balloon catheter, Solid state catheter
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 15, 2008 · Synced Jul 21, 2026, 6:11 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fecal Incontinence Subtypes in Women With Pelvic Floor Disorders

NCT02772874
View directory record Official record
Conditions
Fecal Incontinence
Interventions
No intervention
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Jul 21, 2026, 6:11 PM EDT
Completed No phase listed Observational

Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas

NCT03321266
View directory record Official record
Conditions
Anorectal Fistula
Interventions
Cook Biodesign® Fistula Plug
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
Not listed
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
3
States / cities
Louisville, Kentucky • Baton Rouge, Louisiana • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated Phase 2 Interventional Results available

Treating Anorectal Dysfunction in MS

NCT02609607
View directory record Official record
Conditions
Constipation, Fecal Incontinence, Multiple Sclerosis
Interventions
Bisacodyl, Placebo
Drug · Other
Lead sponsor
David Levinthal
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury

NCT05626816
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Genital Nerve Stimulation, Clinical exam, Collection of SCI common data elements, Bowel function survey completion, International Standard for Neurological Classification of SCI (ISNCSCI), Response to genital nerve stimulation (GNS), Anorectal Manometry testing (ARM)
Device · Diagnostic Test
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VR to Reduce Pain/Anxiety During Painful Procedures

NCT04268901
View directory record Official record
Conditions
Phlebotomy, Orthopedics, Radiology, Pain, Anxiety, Virtual Reality, Allergy, Gastroenterology
Interventions
Samsung Gear VR, Merge VR, Oculus Go
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
7 Years to 21 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Mechano-physiological Approach to Anorectal Function

NCT00219518
View directory record Official record
Conditions
Constipation
Interventions
defecography
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 24, 2018 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated Not applicable Interventional Results available

Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft

NCT00610207
View directory record Official record
Conditions
Anal Fistula, Crohn's Disease
Interventions
Surgisis Biodesign Anal Fistula Plug (SurgiSIS AFP)
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
3
States / cities
Los Angeles, California • New York, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Jul 21, 2026, 6:11 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

NCT03302858
View directory record Official record
Conditions
HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer, HPV-Related Squamous Cell Carcinoma, Human Papilloma Virus, Human Papillomavirus Infection, Ain III
Interventions
BARRX™ Anorectal Wand
Device
Lead sponsor
Stephen E. Goldstone
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Jul 21, 2026, 6:11 PM EDT
Enrolling by invitation Not applicable Interventional

Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids

NCT07161765
View directory record Official record
Conditions
Bleeding Hemorrhoids, Rectal Evacuation Disorders
Interventions
Anorectal manometry
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial to Evaluate Fecobionics in Healthy Subjects and Patients

NCT04766138
View directory record Official record
Conditions
Normal Subjects, Fecal Incontinence
Interventions
Fecobionics
Device
Lead sponsor
The California Medical Innovations Institute, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Efficacy of a Wearable Noninvasive Neuromodulation Device

NCT07171489
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
TNM at a sham-point (AccelBand) - randomized arm, TNM at a leg point (AccelBand)- randomized arm, TNM at a leg point (AccelBand)- open-label
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery

NCT03738904
View directory record Official record
Conditions
Anorectal Disorder
Interventions
ERAS, Standard of care
Combination Product
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2023 · Synced Jul 21, 2026, 6:11 PM EDT
Terminated Not applicable Interventional Results available

Treatment of Patients With Fecal Incontinence

NCT00292318
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Biofeedback Therapy for Fecal Incontinence: A Randomized Control Study, control group
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Sepulveda, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Anal Sphincter Prosthesis in Treating Patients Who Are Undergoing Surgery for Anal or Rectal Cancer

NCT00059891
View directory record Official record
Conditions
Anal Cancer, Colorectal Cancer, Perioperative/Postoperative Complications
Interventions
conventional surgery, management of therapy complications
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2013 · Synced Jul 21, 2026, 6:11 PM EDT