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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:58 PM EDT

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Showing 1–24 of 61 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Apnea Neonatal Clear all
Completed No phase listed Observational Accepts healthy volunteers

Sleep and Behavior in Children With Cleft Palate

NCT01046591
View directory record Official record
Conditions
Cleft Palate
Interventions
Polysomnography
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 15 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Oct 20, 2026, 4:58 PM EDT
Enrolling by invitation Not applicable Interventional

Long-term Evaluation of Nasopharyngeal Airway in Hypotonia

NCT06614582
View directory record Official record
Conditions
Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 23 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

NCT01808508
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea Syndrome
Interventions
Continuous positive airway pressure, Sham or placebo continuous positive airway pressure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 20 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 20, 2026, 4:58 PM EDT
Terminated Not applicable Interventional

Early Versus Late Caffeine for ELBW Newborns

NCT02524249
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Apnea of Prematurity
Interventions
Caffeine, Placebo (dextrose)
Drug
Lead sponsor
Wayne State University
Other
Eligibility
Up to 4 Weeks
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 20, 2026, 4:58 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Treatment of Children With Obstructive Sleep Apnea and Laryngomalacia: the Role of Laser Supraglottoplasty

NCT00394550
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Respiration Disorders
Interventions
supraglottoplasty with laser
Procedure
Lead sponsor
Indiana University
Other
Eligibility
1 Year to 18 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 20, 2026, 4:58 PM EDT
Completed No phase listed Observational

Effect of Feedings on Caffeine in Premature Infants

NCT02293824
View directory record Official record
Conditions
Apnea of Prematurity, Premature Newborn, Caffeine
Interventions
Caffeine
Drug
Lead sponsor
Duke University
Other
Eligibility
Up to 15 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Oct 20, 2026, 4:58 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Substantial Equivalence Study for Kai Medical Non-Contact Respiratory Rate Monitors for Use With Neonates

NCT01324817
View directory record Official record
Conditions
Respiration
Interventions
Kai Spot (v 2.1), Kai Continuous (v 1.0)
Device
Lead sponsor
Kai Medical, Inc.
Industry
Eligibility
Up to 2 Months
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Dec 14, 2011 · Synced Oct 20, 2026, 4:58 PM EDT
Recruiting Phase 2 Interventional

Down Syndrome Obstructive Sleep Apnea

NCT06043440
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Oxygen
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Los Angeles, California • Ann Arbor, Michigan • Cincinnati, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 20, 2026, 4:58 PM EDT
Recruiting Not applicable Interventional

Pediatric Down Syndrome Post-Approval Study

NCT06851338
View directory record Official record
Conditions
Pediatric Obstructive Sleep Apnea, Down Syndrome (DS)
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
13 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
6
States / cities
Phoenix, Arizona • Orange, California • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 20, 2026, 4:58 PM EDT
Recruiting Not applicable Interventional

The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants

NCT05298748
View directory record Official record
Conditions
Apnea of Prematurity, Intermittent Hypoxemia, Bradycardia
Interventions
Womb sound recordings
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
1 Week to 5 Weeks
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)

NCT04124471
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Open-ended semi-structured interviews
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 20, 2026, 4:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sleep Apnea in Pregnancy Screening Study

NCT01585844
View directory record Official record
Conditions
Sleep Apnea, Obesity
Interventions
Not listed
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 20, 2026, 4:58 PM EDT
Completed No phase listed Observational

Healthy Sleep for Children With Down Syndrome

NCT03922165
View directory record Official record
Conditions
Down Syndrome, Sleep Disordered Breathing
Interventions
Adenotonsillectomy
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
3 Years to 13 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
6
States / cities
Ann Arbor, Michigan • Cincinnati, Ohio • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 20, 2026, 4:58 PM EDT
Recruiting Phase 2 Interventional

Caffeine Optimization for Oxygen Saturation Index in ELBW Infants

NCT07216365
View directory record Official record
Conditions
Neonatal Apnea, Infants
Interventions
Caffeine Citrate
Drug
Lead sponsor
University of Rochester
Other
Eligibility
0 Days to 27 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 20, 2026, 4:58 PM EDT
Active, not recruiting Phase 2 Interventional

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome

NCT05933603
View directory record Official record
Conditions
Obstructive Sleep Apnea, Down Syndrome
Interventions
Atomoxetine and Oxybutynin (ato-oxy)
Drug
Lead sponsor
University of Arizona
Other
Eligibility
6 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx

NCT03986671
View directory record Official record
Conditions
Obstructive Sleep Apnea, Amyotrophic Lateral Sclerosis, Muscular Dystrophies, Healthy
Interventions
Transmembrane EMG Oropharynx Probe
Device
Lead sponsor
Powell Mansfield Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 20, 2026, 4:58 PM EDT
Completed No phase listed Observational Results available

Comorbidities Associated With Migraine and Patent Foramen Ovale (CAMP)

NCT01257880
View directory record Official record
Conditions
Migraine With Aura, Patent Foramen Ovale
Interventions
Not listed
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 27, 2011 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea

NCT02344108
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Down Syndrome
Interventions
Inspire® Upper Airway Simulation System (Model 3028 IPG )
Device
Lead sponsor
Christopher Hartnick, M.D.
Other
Eligibility
10 Years to 21 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
5
States / cities
Atlanta, Georgia • Boston, Massachusetts • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)

NCT04132999
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Family-informed intervention, Standard Clinical Care
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
6 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Miami, Florida • Cincinnati, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 20, 2026, 4:58 PM EDT
Completed No phase listed Observational

Factors Predictive of Adverse Postoperative Outcomes in Children Undergoing Tonsillectomy

NCT01669993
View directory record Official record
Conditions
Tonsillectomy Postoperative Adverse Events
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 17 Years
Enrollment
2,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 20, 2026, 4:58 PM EDT
Terminated Phase 3 Interventional

Right to Left Cardiac Shunt Detection

NCT01773252
View directory record Official record
Conditions
Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
Interventions
Flow Detection System
Device
Lead sponsor
Cardiox Corporation
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
8
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Providing Oxygen During Intubation in the NICU Trial

NCT05451953
View directory record Official record
Conditions
Neonatal Respiratory Failure, Tracheal Intubation Morbidity
Interventions
Apneic Oxygenation, Standard of Care
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
0 Days to 365 Days
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 20, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants

NCT05968586
View directory record Official record
Conditions
Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
Interventions
Body positioning
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Minute to 3 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 20, 2026, 4:58 PM EDT
Completed No phase listed Observational

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome

NCT01902407
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year to 90 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 4:58 PM EDT