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Conditions: Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
Interventions: Intravenous and Intranasal BMSC; Procedure
Lead sponsor: MD Stem Cells; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2028
U.S. locations: 2
States / cities: Westport, Connecticut • Coral Springs, Florida

Conditions: Subdural Hematoma
Interventions: NeoCast Embolic System, Onyx LES, an FDA-Approved Commercial Liquid Embolic; Device
Lead sponsor: Arsenal Medical, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: New Haven, Connecticut • Seattle, Washington

Conditions: Ruptured Cerebral Aneurysm, Subarachnoid Hemorrhage (SAH)
Interventions: coil embolization, clip occlusion; Procedure
Lead sponsor: St. Joseph's Hospital and Medical Center, Phoenix; Other
Eligibility: 18 Years to 80 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2023
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Cerebral Vasospasm
Interventions: Nicardipine, Verapamil, Nicardipine + Verapamil + Nitroglycerin; Drug
Lead sponsor: Peng Roc Chen, MD; Other
Eligibility: 18 Years to 80 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2024
U.S. locations: 5
States / cities: New Haven, Connecticut • Manhasset, New York • Winston-Salem, North Carolina + 2 more

Conditions: Coronary Artery Disease
Interventions: Ticagrelor 90 mg, Prasugrel 10 mg; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 75 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Hemorrhagic Shock, Trauma, Wounds, Penetrating, Shock, Traumatic, Multiple Trauma
Interventions: Intraoperative Hypotensive Resuscitation; Procedure
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 12 Years to 45 Years
Enrollment: 271 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:; Drug
Lead sponsor: Daniel Benjamin; Other
Eligibility: Up to 21 Years
Enrollment: 3,520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 43
States / cities: Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more

Conditions: Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH), Intracerebral Hemorrhage Basal Ganglia, Ischemic Stroke, Ischemic Stroke and Hemorrhagic Stroke, Hemiparesis After Stroke, Hemiplegia Following Ischemic Stroke, Hemiplegia and Hemiparesis, Hemiplegia and/or Hemiparesis Following Stroke, Middle Cerebral Artery Stroke
Interventions: Psilocybin (Usona Institute); Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Peripheral Vascular Disease, Peripheral Artery Disease, Carotid Stenosis, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Amputation, Wound, Embolism and Thrombosis, Aortic Aneurysm
Interventions: Not listed
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: New York, New York

Conditions: Arterial Occlusion, Cardiovascular Diseases, Hematoma
Interventions: Perclose, Statseal; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Chronic Subdural Hematoma, Hemorrhage Brain
Interventions: Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Intracranial Aneurysm
Interventions: Ultrasound; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Coronary Artery Disease
Interventions: Device: Medtronic Resolute Onyx Zotarolimus-Eluting Coronary Stent System Treatment Followed by one-month DAPT; Combination Product
Lead sponsor: Medtronic Vascular; Industry
Eligibility: 18 Years and older
Enrollment: 752 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 4
States / cities: East Syracuse, New York • New York, New York • Anderson, South Carolina + 1 more

Conditions: Intracranial Hemorrhage Ruptured Aneurysm
Interventions: surgical management, Endovascular management; Procedure
Lead sponsor: Centre hospitalier de l'Université de Montréal (CHUM); Other
Eligibility: 18 Years and older
Enrollment: 1,724 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2024
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Alagille Syndrome, Pulmonary Artery Stenoses, Acquired Von Willebrand Disease
Interventions: Assessment for bleeding disorder with tailored post-operative care; Other
Lead sponsor: Stanford University; Other
Eligibility: Up to 17 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Chronic Subdural Hematoma
Interventions: Not listed
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 18
States / cities: Coral Gables, Florida • Jacksonville, Florida • Miami, Florida + 13 more

Conditions: Acute Ischemic Stroke
Interventions: Intra-arterial Tenecteplase, Intra-arterial Saline; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Coronary Artery Disease
Interventions: Clopidogrel withdraw prior to CABG; Other
Lead sponsor: LifeBridge Health; Other
Eligibility: 18 Years to 85 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Coronary Artery Lesions
Interventions: XIENCE, DAPT; Device · Drug
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 2,047 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 101
States / cities: Huntsville, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 88 more

Conditions: Coronary Artery Disease
Interventions: Early Bird® Bleed Monitoring System, Impella®; Device
Lead sponsor: Saranas, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 203 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 11
States / cities: Phoenix, Arizona • Tucson, Arizona • Gary, Indiana + 7 more

Conditions: Chronic Subdural Hematoma
Interventions: Experimental: Interventional Cohort: TRUFILL n-Butyl Cyanoacrylate (n-BCA) Liquid Embolic System, Standard of Care Surgery, Experimental: Interventional Cohort: TRUFILL n-BCA Liquid Embolic System, Standard of Care Medical Management; Device · Other
Lead sponsor: Cerenovus, Part of DePuy Synthes Products, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 376 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 31
States / cities: Birmingham, Alabama • Tucson, Arizona • Walnut Creek, California + 28 more

Conditions: Coronary Artery Disease, Myocardial Ischemia, Bleeding
Interventions: clopidogrel 600 mg, arterial access sheath; Drug · Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stroke, Neurologic Diseases, General
Interventions: NC-758 (Anti amyloidotic [Aß] agent); Drug
Lead sponsor: Bellus Health Inc. - a GSK company; Industry
Eligibility: 55 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 5
States / cities: Lexington, Kentucky • Boston, Massachusetts • New York, New York + 2 more

Conditions: Intracranial Hemorrhages, Prematurity
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: Up to 14 Days
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Nashville, Tennessee

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Neurologic Stem Cell Treatment Study

MMA Embolization With NeoCast for Subacute and Chronic Subdural Hematoma

Barrow Ruptured Aneurysm Trial

The Intra-arterial Vasospasm Trial

Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors

A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Platelet Activity in Vascular Surgery for Thrombosis and Bleeding

Comparing Perclose to Statseal With Perclose in Transcatheter Aortic Valve Replacement Arteriotomy Closure

Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center

Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study

A Single Arm Trial With Resolute Onyx in ONE-Month DAPT for High-Bleeding Risk Patients Who Are Considered One-Month Clear (Onyx ONE Clear)

International Subarachnoid Aneurysm Trial II

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

Intra-Arterial Tenecteplase Following Endovascular Thrombectomy for Large Vessel Occlusion Stroke

Time Based Strategy to Reduce Clopidogrel Associated Bleeding Related to Coronary Artery Bypass Graft (CABG)

XIENCE 90: A Safety Evaluation of 3-month DAPT After XIENCE Implantation for HBR Patients.

Safe Surveillance of PCI Under Mechanical Circulatory Support With the Saranas Early Bird Bleed Monitoring System

Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA

Role of Plavix in Hemorrhagic and Ischemic Complications of Catheterization.

Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy

Neurophysiology and Anatomy of Severe Intraventricular Hemorrhage (IVH)