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ClinicalTrials.gov public records Last synced Oct 2, 2026, 7:52 PM EDT

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Showing 25–48 of 476 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Arthroplasty, Replacement Clear all
Not listed Not applicable Interventional

'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients

NCT01874379
View directory record Official record
Conditions
Hip or Knee Replacement
Interventions
'M'-Technique®, Guided Imagery, Standard of Care
Other
Lead sponsor
Saint Clare's Health System
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Denville, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 11, 2013 · Synced Oct 2, 2026, 7:52 PM EDT
Active, not recruiting Not applicable Interventional Results available

Triathlon Tritanium Cone Augments Outcomes Study

NCT02521103
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Triathlon Tritanium Cone Augments
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
9
States / cities
Zephyrhills, Florida • Chicago, Illinois • Lexington, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Phase 3 Interventional

Study of Safety, Efficacy of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3007

NCT02301234
View directory record Official record
Conditions
Osteoarthritis, Pain
Interventions
Placebo, Fulranumab 1 mg, Fulranumab 3 mg, Celecoxib 100 mg, Celecoxib 100 mg Matching Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
32
States / cities
Glendale, Arizona • Phoenix, Arizona • Tucson, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Oct 2, 2026, 7:52 PM EDT
Terminated No phase listed Observational Results available

A Post-Market Clinical Evaluation of the ReUnion Reversible Fracture (RFX) System

NCT04089371
View directory record Official record
Conditions
Arthroplasty, Hemiarthroplasty, Shoulder Pain
Interventions
ReUnion Total Shoulder Arthroplasty (TSA), ReUnion Reverse Shoulder Arthroplasty (RSA)
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Peoria, Illinois • Greenville, South Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

A Rehabilitation Tool to Determine Patient's Stay in Hospital After Joint Replacement

NCT03777007
View directory record Official record
Conditions
Total Joint Replacement Surgery
Interventions
SPARTA force plate
Device
Lead sponsor
Derek Amanatullah
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Phase 3 Interventional Results available

Evaluation of Preoperative N1539 in Total Knee Arthroplasty

NCT03434275
View directory record Official record
Conditions
Pain, Postoperative
Interventions
N1539, Placebo
Drug
Lead sponsor
Baudax Bio
Industry
Eligibility
35 Years to 80 Years
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
6
States / cities
Florence, Alabama • Mobile, Alabama • Sheffield, Alabama + 3 more
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 2, 2026, 7:52 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Swelling Management After Knee Replacement

NCT06095401
View directory record Official record
Conditions
Arthroplasties, Knee Replacement
Interventions
Inelastic adjustable compression garment (INCOM), Elastic compression garment (CONTROL)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 120 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 2, 2026, 7:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA)

NCT01359527
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
Hip Resurfacing, Total Hip Arthroplasty
Device
Lead sponsor
Spokane Joint Replacement Center
Other
Eligibility
20 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 2, 2026, 7:52 PM EDT
Terminated Phase 4 Interventional Results available

US Guided GNB vs Saline Injection for TKA

NCT03316118
View directory record Official record
Conditions
Postoperative Pain, Total Knee Arthroplasty, Nerve Block
Interventions
bupivacaine, saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Robotic Assisted TKA

NCT06062615
View directory record Official record
Conditions
Total Knee Replacement
Interventions
Total knee replacement using Omnibot Knee System, Conventional Total knee replacement, Omnibot Robotic Knee System
Procedure · Device
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 2, 2026, 7:52 PM EDT
Not yet recruiting Not applicable Interventional

Multimodal Analgesic Regimen for Total Hip Arthroplasty: An Initiative to Minimize Postoperative Opioid Use

NCT07672808
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
Standard Multimodal Analgesic Regimen with Opioid Prescription, Opioid-Reduced Multimodal Analgesic Regimen with Printed Prescription
Drug · Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional

Increasing Awareness of Opioid Disposal in the Orthopedic Patient Population

NCT03954964
View directory record Official record
Conditions
Knee Total Joint Replacement, Hip Total Joint Replacement
Interventions
Education on disposal of opioids
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 2, 2026, 7:52 PM EDT
Terminated Not applicable Interventional Results available

A Rehabilitation Tool to Determine Patient's Stay in Hospital After Joint Replacement

NCT03776357
View directory record Official record
Conditions
Total Joint Replacement Surgery
Interventions
VERA clinic
Device
Lead sponsor
Derek Amanatullah
Other
Eligibility
18 Years to 99 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 2, 2026, 7:52 PM EDT
Completed No phase listed Observational Results available

THA Kinematics and Sound for Subjects Implanted Using Various Surgical Approaches

NCT01833481
View directory record Official record
Conditions
Hip Injuries
Interventions
Fluoroscopy surveillance of patients while walking
Radiation
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
40 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Towson, Maryland • Renton, Washington
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Phase 2 Interventional

Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery

NCT02807428
View directory record Official record
Conditions
Post-surgical Pain
Interventions
AYX1 Injection 660 mg/6 mL, Placebo Injection 6 mL
Drug
Lead sponsor
Adynxx, Inc.
Industry
Eligibility
40 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
9
States / cities
Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 2, 2026, 7:52 PM EDT
Terminated Phase 4 Interventional

Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System

NCT00546598
View directory record Official record
Conditions
Non-inflammatory Joint Disease, Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Post-traumatic Arthritis
Interventions
Total hip replacement/arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
21 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
6
States / cities
Atlanta, Georgia • Springfield, Illinois • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery

NCT00393848
View directory record Official record
Conditions
Hip Fracture, Osteoarthritis, Femur Head Necrosis
Interventions
Essential amino acid supplement, Ketoconazole, Placebo
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 2, 2026, 7:52 PM EDT
Withdrawn Not applicable Interventional

Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis

NCT06513559
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Anatomic total shoulder replacement, Reverse total shoulder replacement
Device
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 2, 2026, 7:52 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Fixed Bearing Versus Mobile Bearing Patient Satisfaction and Clinical Outcome Study

NCT02633085
View directory record Official record
Conditions
Osteoarthritis
Interventions
Fixed Bearing or Mobile Bearing UKA
Device
Lead sponsor
Medacta USA
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Leesburg, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional

A Randomized Study of Approaches in Total Hip Arthroplasty

NCT01613508
View directory record Official record
Conditions
Total Hip Replacement
Interventions
Direct Anterior Approach, Mini-Posterior Approach
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 100 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 5, 2018 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

Ceramic-on-Ceramic (COC) 36mm Acetabular Bearing Insert Post Approval Study-New Subjects (COC36mmPAS)

NCT02096211
View directory record Official record
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
Interventions
COC 36mm
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
21 Years to 75 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
9
States / cities
Sacramento, California • Denver, Colorado • Tampa, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery

NCT01693900
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Pre-operative Ultrasound FICB Group, Intra-operative FICB Group
Procedure
Lead sponsor
Randy Fayne, DO
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 15, 2018 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional

The Effect of a Psychosensory Therapy

NCT02765932
View directory record Official record
Conditions
Joint Replacement Surgery
Interventions
Dummy Movements, Psychosensory Therapy
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Oct 2, 2026, 7:52 PM EDT
Completed Not applicable Interventional

Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement

NCT00594893
View directory record Official record
Conditions
Osteoarthritis
Interventions
Mini Incision Approach, 2 Incision Approach
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 31, 2012 · Synced Oct 2, 2026, 7:52 PM EDT