Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 9, 2026, 12:33 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cataract, Corneal Astigmatism
Interventions
RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Rayner Intraocular Lenses Limited
Industry
Eligibility
22 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
9
States / cities
Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more
Conditions
Myopia, Astigmatism
Interventions
kalifilcon A Daily Disposable Toric, Ultra for Astigmatism Contact Lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Rochester, New York
Conditions
Cataracts, Astigmatism
Interventions
Abbott WHITESTAR Signature System with Ellips Transversal Ultrasound, Alcon Infiniti wiht the OZIL Torsional Handpiece
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Beverly Hills, California
Conditions
Astigmatism
Interventions
Investigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology (4GT) lines with extended mini-stack hydration using propylene glycol (PG) as the hydration solvent., ACUVUE® Oasys 1-Day for Astigmatism (AO1DfA) soft contact lenses manufactured on 3rd Generation Technology (3GT) legacy lines using isopropyl alcohol (IPA) as the hydration solvent.
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
281 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
20
States / cities
Mission Viejo, California • San Diego, California • Jacksonville, Florida + 16 more
Completed Not applicable Interventional Results available

Toric Intraocular Lens Following Cataract Surgery

NCT01140477
Conditions
Cataract, Astigmatism
Interventions
Toric Accommodating Lens, Accommodating Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Hyperopia, Myopia, Astigmatism
Interventions
LASIK and PRK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate Effectiveness of Digital Refraction

NCT03502863
Conditions
Myopia, Astigmatism
Interventions
Digital refraction, Manual Refraction
Device · Other
Lead sponsor
Visibly
Industry
Eligibility
22 Years to 55 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
3
States / cities
Fort Lauderdale, Florida • Nashville, Tennessee • Harlingen, Texas
Conditions
Myopia
Interventions
Corneal Refractive Therapy-spherical, Corneal Refractive Therapy-aspherical
Other
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Aphakia, Cataract
Interventions
FY-60AD, NHT15, NHT30, & NHT53
Device
Lead sponsor
Hoya Surgical Optics, Inc.
Industry
Eligibility
50 Years and older
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
6
States / cities
Chino Hills, California • Santa Maria, California • Mt. Dora, Florida + 3 more
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Conditions
Cataracts, Cataract Surgery
Interventions
Lens insertion during cataract surgery
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Spectacle Prescribing in Early Childhood

NCT04728451
Conditions
Astigmatism Bilateral, Eyeglasses
Interventions
Spectacle wear support, Spectacles
Behavioral · Device
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 35 Months
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Myopia, Astigmatism
Interventions
Contoura LASIK with Phorcides planning strategy, Contoura LASIK with manifest refraction planning strategy
Device
Lead sponsor
Bismarck Lasik
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bismarck, North Dakota
Conditions
Astigmatism
Interventions
CATARACT SURGERY
Procedure
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Refractive Errors, Astigmatism
Interventions
Verofilcon A toric contact lenses, Stenfilcon A toric contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
6
States / cities
Maitland, Florida • Pittsburg, Kansas • Sterling Heights, Michigan + 3 more
Conditions
Astigmatism
Interventions
etafilcon A toric contact lens with new wetting agent, etafilcon A toric contact lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
2
States / cities
Jacksonville, Florida • New York, New York
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Conditions
Myopia, Hyperopia, Presbyopia, Astigmatism
Interventions
Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
7 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
San Diego, California • Ponte Vedra Beach, Florida • West Palm Beach, Florida + 8 more
Conditions
Myopia, Astigmatism
Interventions
Photorefractive keratectomy, Laser in-situ keratomileusis
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Stanford, California
Conditions
Astigmatism, Cataract
Interventions
Femtosecond laser assisted cataract surgery with astigmatism management
Procedure
Lead sponsor
Kenneth J Rosenthal
Other
Eligibility
18 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Not yet recruiting No phase listed Observational

Revive Toric RWE Study

NCT06785194
Conditions
Astigmatism
Interventions
REVIVE samfilcon B custom toric contact lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Timeline
2026
U.S. locations
3
States / cities
Orange Park, Florida • Canton, Georgia
Conditions
Refractive Errors, Astigmatism
Interventions
Hand-held device supported by a mobile application, Phoropter, Autorefractor
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
30 Years to 65 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Inglewood, California
Conditions
Aphakia, Cataract
Interventions
Light Delivery Device (LDD)
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Brecksville, Ohio • Sioux Falls, South Dakota