- Conditions
- Preterm Infants, Respiratory Distress Syndrome (Neonatal), BPD - Bronchopulmonary Dysplasia
- Interventions
- Pressure Targeted High Flow, CPAP
- Procedure
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 7 Days to 40 Weeks
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- San Diego, California • Austin, Texas
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Showing 1–24
of 49
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Interventions
- Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
- Procedure
- Lead sponsor
- Sharp HealthCare
- Other
- Eligibility
- 24 Weeks to 29 Weeks
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 3
- States / cities
- Irvine, California • Loma Linda, California • San Diego, California
- Conditions
- Atelectasis
- Interventions
- Normal saline:, Hypertonic Saline, Dornase alpha
- Drug
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Respiratory Insufficiency, Pneumonia, Atelectasis
- Interventions
- Bronchoscope reusable (Storz 8402 2x), Bronchoscope disposable (aScope 4)
- Device
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Post-Op Infection, Adherence, Patient, Pulmonary Atelectasis, Incentive Spirometry, Post-Op Complication
- Interventions
- Smartphone Arm
- Behavioral
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Postoperative Atelectasis
- Interventions
- Incentive spirometer, GO2 Mouthpiece
- Device
- Lead sponsor
- Emory University
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Atelectasis, Bronchoscopy
- Interventions
- Bronchoscopic procedure
- Device
- Lead sponsor
- Ambu A/S
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Respiratory Failure
- Interventions
- Hypertonic saline (3%), Placebo (0.9% saline)
- Drug
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Atelectasis
- Interventions
- Ventilating the patient with lower (40 or 70%) oxygen concentration during the wash out phase, before extubation
- Procedure
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging, Respiratory Mechanics, Electrical Impedance Tomography, Trans-Thoracic Echocardiography
- Interventions
- Non-Invasive Ventilation, Esophageal catheter positioning
- Procedure
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Atelectasis
- Interventions
- Incentive Spirometry, EzPAP® Positive Airway Pressure
- Device
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Surfactant, Respiratory Distress Syndrome (Neonatal)
- Interventions
- Surfactant Administration through Laryngeal or Supraglottic Airway, Surfactant Administration through Thin Catheter
- Procedure
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 0 Hours to 72 Hours
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements, FEV1, FVC, Atelectasis, Pneumonia, Re-intubation, Hospital Length of Stay, Nursing Workload, Incentive Spirometry
- Interventions
- Use-recording, patient-reminder alarm for incentive spirometry
- Behavioral
- Lead sponsor
- Lifespan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Pre-Term, Respiratory Distress of Newborn, Premature
- Interventions
- Point of care lung ultrasound
- Diagnostic Test
- Lead sponsor
- Hackensack Meridian Health
- Other
- Eligibility
- 34 Weeks to 36 Weeks
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Hackensack, New Jersey
- Conditions
- Lung Disorder
- Interventions
- Anesthesia Procedure, Bronchoscopy
- Procedure
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Atelectasis, Pulmonary Complications
- Interventions
- MetaNeb® System
- Device
- Lead sponsor
- Hill-Rom
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 419 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 3
- States / cities
- Burlington, Massachusetts • Charlotte, North Carolina • Philadelphia, Pennsylvania
- Conditions
- Moderate Persistent Asthma, Severe Persistent Asthma, Nodule Solitary Pulmonary, Pulmonary Atelectasis
- Interventions
- Bronchial biopsy
- Procedure
- Lead sponsor
- Lu Yuan Lee
- Other
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
- Interventions
- Infasurf Aero™
- Combination Product
- Lead sponsor
- ONY
- Industry
- Eligibility
- 29 Weeks to 36 Weeks
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 10
- States / cities
- Phoenix, Arizona • San Diego, California • Jacksonville, Florida + 6 more
- Conditions
- Chemical Injury, Chemicals; Intoxication, Acute Respiratory Distress Syndrome, Distress Respiratory Syndrome, Medical Emergencies
- Interventions
- Clinical interventions performed in acute settings (contaminated environment), Protection (clinician and patient), Decontamination (clinician and patient)
- Procedure
- Lead sponsor
- St. Justine's Hospital
- Other
- Eligibility
- Not listed
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2036
- U.S. locations
- 1
- States / cities
- College Park, Maryland
- Conditions
- Respiratory Distress of Newborn
- Interventions
- Ultrasound
- Device
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- Up to 6 Months
- Enrollment
- 71 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota • Madison, Wisconsin
- Conditions
- Neonatal Respiratory Distress
- Interventions
- RAM Nasal Cannula
- Other
- Lead sponsor
- Englewood Hospital and Medical Center
- Other
- Eligibility
- 28 Weeks to 42 Weeks
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Englewood, New Jersey
- Conditions
- Respiratory Distress Syndrome, Newborn
- Interventions
- Surfactant administered via Laryngeal Mask Airway (LMA), standard of care (nasal CPAP and supplemental oxygen)
- Device · Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- Up to 72 Hours
- Enrollment
- 380 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Atelectasis
- Interventions
- The MetaNeb® System
- Device
- Lead sponsor
- Hill-Rom
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Newport Beach, California
- Conditions
- Atelectasis
- Interventions
- FiO2 (fraction of inspired oxygen) 0.3 plus PEEP (positive end expiratory pressure) 3 -5 cm water, FiO2 0.3 without PEEP, FiO2 >0.9 with 3-5 cm water PEEP, FiO2 >0.9 without PEEP
- Other
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah