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Showing 1–24 of 90 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Body Water Dehydration Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Recombinant Hyaluronidase in Out-of-Hospital Setting: The EASI Access Trial

NCT00386386
View directory record Official record
Conditions
Mass Casualty Incident, Dehydration
Interventions
hypodermoclysis via recombinant hyaluronidase-facilitated subcutaneous infusion
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2008 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Beverage Hydration Index" of Commercial Therapeutic Beverages

NCT03262597
View directory record Official record
Conditions
Healthy
Interventions
enterade, Pedialyte, Gatorade, Water
Other
Lead sponsor
Sonoma State University
Other
Eligibility
18 Years to 35 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Rohnert Park, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2018 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Urine Color as a Marker of Hydration Status

NCT05174793
View directory record Official record
Conditions
Dehydration
Interventions
dehydration and rehydration
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 2, 2022 · Synced Jul 22, 2026, 7:37 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Physician Perceptions About Parenteral Hydration in Latin America and Spain

NCT01011140
View directory record Official record
Conditions
Dehydration, Advanced Cancers
Interventions
Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2019 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LifeFlow Fluid Study- Non- Critical Pediatric Patients Having a Trans Abdominal Ultrasound

NCT03712189
View directory record Official record
Conditions
Dehydration in Children, Dehydration
Interventions
LifeFlow
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Month to 18 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2024 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rehydration Efficiency With Different Sports Drinks

NCT06415409
View directory record Official record
Conditions
Dehydration
Interventions
Water, Gatorade, BodyArmor, GoodSport
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jul 22, 2026, 7:37 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A)

NCT01116102
View directory record Official record
Conditions
Dehydration
Interventions
Subcutaneous HYLENEX (recombinant human hyaluronidase) and Lactated Ringer's solution
Drug
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2011 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers

NCT04076995
View directory record Official record
Conditions
Dehydration, Diabetes Mellitus, Type 2
Interventions
Water Intake
Other
Lead sponsor
Arizona State University
Other
Eligibility
30 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parenteral Hydration in Advanced Cancer Patients

NCT00423722
View directory record Official record
Conditions
Advanced Cancer, Dehydration
Interventions
Saline
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
5
States / cities
Conroe, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

EASI Access II --- Follow-up Study to the EASI Access Trial

NCT00740727
View directory record Official record
Conditions
Disaster Medicine, Difficult Intravenous Access, Dehydration
Interventions
Human recombinant hyaluronidase (HRH), Enzymatically Augmented Subcutaneous Infusion (EASI) line placement
Drug · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2009 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Oral Carbohydrate Consumption Prior to Cesarean Section

NCT02684513
View directory record Official record
Conditions
Dehydration
Interventions
Oral Carbohydrate Beverage, Rehydration beverage
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

NCT06042270
View directory record Official record
Conditions
Body Temperature Changes, Body Water Dehydration, Inflammation
Interventions
Betaine, Placebo
Dietary Supplement
Lead sponsor
Michael J. Ormsbee
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Jul 22, 2026, 7:37 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Carbohydrate Blends and Electrolytes on Physical and Mental Performance During Cycling in the Heat

NCT07658820
View directory record Official record
Conditions
Hydration, Dehydration (Physiology), Performance
Interventions
Water (Placebo), Carbohydrate Milk Permeate sports drink, 6% Sports drink, Low-Carbohydrate Milk Permeate sports drink
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 22, 2026, 7:37 PM EDT
Terminated Phase 3 Interventional Results available

Use of Post Operative Loperamide in Colorectal Patients After Diverting Ileostomies

NCT02263365
View directory record Official record
Conditions
Dehydration, Diverting Ileostomy, Loperamide
Interventions
Loperamide
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Methods of Assessing Sweat-Electrolyte Testing (MAST)

NCT07490756
View directory record Official record
Conditions
Sweat Sodium Concentration
Interventions
Wearing the hDrop hydration sensor
Device
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional

DRIHNC - Dehydration Reduction in Head & Neck Cancer

NCT03799380
View directory record Official record
Conditions
Dehydration, Head & Neck Cancer, Esophageal Cancer
Interventions
Gatorade G2, Standard of care nutritional support
Dietary Supplement
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Kids Rehydration During Exercise

NCT05989607
View directory record Official record
Conditions
Dehydration in Children, Dehydration Following Exertion (Disorder)
Interventions
Lower sugar flavored water, Plain Water
Other
Lead sponsor
University of Hartford
Other
Eligibility
8 Years to 10 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Jul 22, 2026, 7:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers for Noninvasive Assessment of Human Hydration

NCT01507129
View directory record Official record
Conditions
Dehydration
Interventions
Not listed
Lead sponsor
Gaia Medical Institute
Industry
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2012 · Synced Jul 22, 2026, 7:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Thirst for Knowledge

NCT07670767
View directory record Official record
Conditions
Geriatric Population
Interventions
Education with a regular hydration opportunity
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Cornwall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 22, 2026, 7:37 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Non-Invasive Optical Spectroscopic Methods for Dehydration Identification in Marathon Trainees

NCT01981902
View directory record Official record
Conditions
Dehydration
Interventions
Non-Invasive Optical Spectroscopic
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Jul 22, 2026, 7:37 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Metabolomic Analysis of the Impacts of Hydration Status on Exercise Performance

NCT02486224
View directory record Official record
Conditions
Dehydration, Physical Exertion, Salivary Osmolar Concentration, Urinary Osmolar Concentration
Interventions
Kona Deep, Spring Water, Sports Drink
Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
20 Years to 25 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Jul 22, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dehydration, Rehydration, and Blood Viscosity

NCT02118883
View directory record Official record
Conditions
Dehydration
Interventions
Essentia Water, Bottled water
Other
Lead sponsor
Essentia Water, LLC
Industry
Eligibility
25 Years to 49 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Jul 22, 2026, 7:37 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Ostom-i Alert System at Decreasing Dehydration Related Complications

NCT02694757
View directory record Official record
Conditions
Ileostomy - Stoma
Interventions
Ostom-i device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Jul 22, 2026, 7:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adequate Hydration and Health Outcomes

NCT07179107
View directory record Official record
Conditions
Dehydration, Dehydration (Physiology), Glucose Abnormalities, Cardiovascular
Interventions
Baseline - week 1, Low Water Intake - week 2, Moderate Water Intake - week 3, Adequate Water Intake - week 4, Washout - week 5, Low fluid intake with non caloric sweeteners - Week 6, Moderate fluid intake with non caloric sweeteners - Week 7, Adequate fluid intake with non caloric sweeteners - Week 8
Other
Lead sponsor
Arizona State University
Other
Eligibility
20 Years to 65 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Jul 22, 2026, 7:37 PM EDT