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ClinicalTrials.gov public records Last synced Sep 11, 2026, 9:32 AM EDT

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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Body Water Dehydration Clear all
Active, not recruiting Not applicable Interventional

Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients

NCT02253238
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Quality of Life Survey, Health Management Surveys, Monitoring Devices, Symptoms Surveys, Device Usability Survey
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Hydration on Gut Health and Thinking

NCT05315531
View directory record Official record
Conditions
Dehydration, Cognitive Change, Gastrointestinal Microbiota
Interventions
Water Intake
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
19 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 11, 2026, 9:32 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Metabolomic Analysis of the Impacts of Hydration Status on Exercise Performance

NCT02486224
View directory record Official record
Conditions
Dehydration, Physical Exertion, Salivary Osmolar Concentration, Urinary Osmolar Concentration
Interventions
Kona Deep, Spring Water, Sports Drink
Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
20 Years to 25 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Sep 11, 2026, 9:32 AM EDT
Completed No phase listed Observational

Tap Water Intake and Perceptions in US Latinx Adults

NCT04997031
View directory record Official record
Conditions
Dehydration
Interventions
Not listed
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
492 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LifeFlow Fluid Study- Non- Critical Pediatric Patients Having a Trans Abdominal Ultrasound

NCT03712189
View directory record Official record
Conditions
Dehydration in Children, Dehydration
Interventions
LifeFlow
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Month to 18 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2024 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Vasopressin on Glucose Regulation

NCT02761434
View directory record Official record
Conditions
Insulin Resistance
Interventions
Hypertonic Saline (3% NaCl), Isotonic Saline (0.9% NaCl)
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
30 Years to 50 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Two Novel Hydration Beverage Formulas on Rehydration in Adults

NCT06063655
View directory record Official record
Conditions
Dehydration
Interventions
Control: Water, Liquid IV hydration multiplier, Liquid IV sugar-free hydration multiplier
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 49 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 11, 2026, 9:32 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparing Speedlyte and IV Rehydration Treating Children With Gastroenteritis in a Pediatric Emergency Department (ED)

NCT03562702
View directory record Official record
Conditions
Dehydration, Acute Gastroenteritis
Interventions
Standard IV Rehydration Therapy, Oral Rehydration Therapy (ORT)
Other
Lead sponsor
Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Other
Eligibility
6 Months to 18 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress

NCT05092854
View directory record Official record
Conditions
Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology), Renal Injury, Electrolyte and Fluid Balance Conditions
Interventions
PR Lotion - AMP Human Performance, Placebo Lotion, AminoVital - Rapid Recovery, Placebo Supplement
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 23, 2022 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Proprietary Water on Physiological and Perceptual Responses

NCT05451446
View directory record Official record
Conditions
Hydration, Dehydration
Interventions
proprietary water, Active comparator, Placebo
Dietary Supplement · Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Renal Considerations in the Heat Stress Recommendations

NCT04767347
View directory record Official record
Conditions
Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia, Dehydration
Interventions
23.0°C WBGT - Fixed Work Rate, 25.5°C WBGT - Fixed Work Rate, 27.5°C WBGT - Fixed Work Rate, 28.5°C WBGT - Fixed Work Rate, 35.5°C WBGT - Fixed Work Rate, 26.0°C WBGT - Fixed work-to-rest ratio, 30.5°C WBGT - Fixed work-to-rest ratio, 30.5°C WBGT - Fixed work-to-rest ratio (high intensity)
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

NCT06042270
View directory record Official record
Conditions
Body Temperature Changes, Body Water Dehydration, Inflammation
Interventions
Betaine, Placebo
Dietary Supplement
Lead sponsor
Michael J. Ormsbee
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dehydration Cognition

NCT05916183
View directory record Official record
Conditions
Dehydration
Interventions
Fluid loss and consumption
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 26 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 11, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Thirst for Knowledge

NCT07670767
View directory record Official record
Conditions
Geriatric Population
Interventions
Education with a regular hydration opportunity
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Cornwall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Kids Rehydration During Exercise

NCT05989607
View directory record Official record
Conditions
Dehydration in Children, Dehydration Following Exertion (Disorder)
Interventions
Lower sugar flavored water, Plain Water
Other
Lead sponsor
University of Hartford
Other
Eligibility
8 Years to 10 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 11, 2026, 9:32 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Reference Values and Determinants of Hydration in Children 3-13 y

NCT02937038
View directory record Official record
Conditions
Dehydration
Interventions
Not listed
Lead sponsor
Arizona State University
Other
Eligibility
3 Years to 13 Years
Enrollment
1,454 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)

NCT01893853
View directory record Official record
Conditions
Dehydration
Interventions
Exercise Intervention
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Sep 11, 2026, 9:32 AM EDT
Completed No phase listed Observational

Mucus Dehydration and Evolution of Chronic Obstructive Pulmonary Disease (COPD) Lung Disease

NCT00903955
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
Interventions
7% hypertonic saline
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 82 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2013 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Water Bolus Volumes During Continuous Exercise in Heat

NCT04613856
View directory record Official record
Conditions
Dehydration (Physiology), Hyperthermia
Interventions
Hydration protocol - 237 mL water bolus, Hydration protocol - 500 mL water bolus
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 11, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers

NCT04076995
View directory record Official record
Conditions
Dehydration, Diabetes Mellitus, Type 2
Interventions
Water Intake
Other
Lead sponsor
Arizona State University
Other
Eligibility
30 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 11, 2026, 9:32 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Non-Invasive Optical Spectroscopic Methods for Dehydration Identification in Marathon Trainees

NCT01981902
View directory record Official record
Conditions
Dehydration
Interventions
Non-Invasive Optical Spectroscopic
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 11, 2026, 9:32 AM EDT
Completed No phase listed Observational

Capillary Refill for Assessment of Dehydration

NCT03670394
View directory record Official record
Conditions
Dehydration in Children
Interventions
Capillary Refill
Diagnostic Test
Lead sponsor
Oregon Health and Science University
Other
Eligibility
6 Months to 10 Years
Enrollment
178 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Sep 11, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dehydration, Rehydration, and Impact on Physiology

NCT07084675
View directory record Official record
Conditions
Aging
Interventions
Hydration-Dehydration-Rehydration Protocol (HDR)
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
45 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 11, 2026, 9:32 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A)

NCT01116102
View directory record Official record
Conditions
Dehydration
Interventions
Subcutaneous HYLENEX (recombinant human hyaluronidase) and Lactated Ringer's solution
Drug
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2011 · Synced Sep 11, 2026, 9:32 AM EDT