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Showing 1–24 of 72 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Bone Resorption Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Skeletal Adaptations to PTH and Exercise

NCT05029128
View directory record Official record
Conditions
Exercise, Bone Resorption, Bone Formation
Interventions
Endurance exercise intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
25 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Marathon and Enduron Polyethylene at Long-Term Follow-up

NCT02508428
View directory record Official record
Conditions
Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Interventions
Hip Replacement with crosslinked Marathon polyethylene, Hip Replacement with noncrosslinked Enduron polyethylene
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
Not listed
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2017
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Effects of Calcium on the Gut-Bone Axis

NCT06383117
View directory record Official record
Conditions
Healthy, Adult, Calcium, Bone Resorption, Endocrine; Obesity
Interventions
Calcium carbonate, Placebo Control
Dietary Supplement
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 45 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Acute Effect of Teriparatide With Bisphosphonate or Denosumab on Bone Resorption

NCT01750086
View directory record Official record
Conditions
Postmenopausal Osteoporosis
Interventions
Teriparatide 40-mcg subcutaneous injection, Denosumab Injection, Alendronate Oral Tablet
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2017 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Intake Modifications to Protect Against Changes in Bone Metabolism

NCT01713634
View directory record Official record
Conditions
Bone Resorption
Interventions
Preflight, In-flight
Other
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
Not listed
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2015 · Synced Jul 21, 2026, 4:56 AM EDT
Terminated No phase listed Observational

Post-Market Study of the Modular Revision Hip System

NCT01464645
View directory record Official record
Conditions
Aseptic Loosening, Osteolysis, Traumatic Fracture, Failed Total Hip Implant
Interventions
Modular Revision Hip System
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
6
States / cities
Burbank, California • Redwood City, California • Syracuse, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials

NCT03149172
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Equimatrix®, Bio-Oss®, Endobon®
Device
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Jul 21, 2026, 4:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Cortical Shield for Facial Bone Reconstruction

NCT04827693
View directory record Official record
Conditions
Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries, Periodontal Bone Loss, Periodontitis, Peri-Implantitis, Tooth Decay
Interventions
Not listed
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Jul 21, 2026, 4:56 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization

NCT05932017
View directory record Official record
Conditions
Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation, Periodontal Attachment Loss, Periodontal Bone Loss, Surgery
Interventions
Not listed
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Jul 21, 2026, 4:56 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Ultrasound for Socket Healing Evaluation

NCT06017193
View directory record Official record
Conditions
Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image, Dent Disease
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation

NCT06173791
View directory record Official record
Conditions
Bone Loss in Jaw
Interventions
DFDBA fibers, DFDBA particles, DBBM
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 21, 2026, 4:56 AM EDT
Recruiting Not applicable Interventional

Alveolar Ridge Preservation (ARP) in the Posterior Maxilla After the Extraction of Maxillary Molars

NCT07433322
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Ossix mineralized grafting immediately at extraction, Delayed grafting at implant placement
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Phase 2 Interventional Results available

Parathyroid Hormone (PTH) for Osteoporosis in Postmenopausal Women

NCT00086619
View directory record Official record
Conditions
Postmenopausal Osteoporosis, Osteoporosis
Interventions
synthetic hPTH 1-34
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
46 Years to 85 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2013 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease

NCT00558272
View directory record Official record
Conditions
Breast Cancer, Prostate Cancer, Bone Neoplasms
Interventions
AZD0530, Zoledronic Acid
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
9
States / cities
Pleasant Hill, California • Sacramento, California • Middlebury, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated May 26, 2013 · Synced Jul 21, 2026, 4:56 AM EDT
Completed No phase listed Observational Results available

A Five-Year Metal-on-Metal Retrospective Clinical Study

NCT01481896
View directory record Official record
Conditions
Osteoarthritis
Interventions
Metal-on-metal primary total hip arthroplasty (DePuy )
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2013 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Effect of Androgen Suppression on Bone Loss in Patients With or Without Bone Metastases Secondary to Prostate Cancer

NCT00003903
View directory record Official record
Conditions
Osteoporosis, Prostate Cancer
Interventions
management of therapy complications
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
Male only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2007
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2013 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Interaction Between Calcium and Vitamin D Intake

NCT00762775
View directory record Official record
Conditions
Osteoporosis
Interventions
Calcium and vitamin D supplementation
Dietary Supplement
Lead sponsor
Winthrop University Hospital
Other
Eligibility
45 Years to 85 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Jul 21, 2026, 4:56 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Synbiotic to Attenuate Resorption of the Skeleton

NCT06389539
View directory record Official record
Conditions
Osteoporosis, Inflammation, Aging
Interventions
SBD111 medical food, Placebo
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Jul 21, 2026, 4:56 AM EDT
Not listed No phase listed Observational

Accuracy of Extra-oral Bite-wing Radiography in Detecting Calculus and Crestal Bone Loss

NCT05887128
View directory record Official record
Conditions
Periodontitis, Calculus, Dental, Bone Loss, Alveolar
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

NCT01121146
View directory record Official record
Conditions
Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Interventions
Total Hip Replacement
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
Not listed
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2012
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 4, 2014 · Synced Jul 21, 2026, 4:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Azento IIS 3 Year Outcomes Implant Study

NCT04255342
View directory record Official record
Conditions
Tooth Loss
Interventions
Implant Placement and Temporary Crown using AstraTech Implant System EV, Final Crown Delivery
Device
Lead sponsor
Christopher Barwacz
Other
Eligibility
18 Years to 95 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Jul 21, 2026, 4:56 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Ph I/II of Vitamin D on Bone Mineral Density & Markers of Bone Resorption

NCT00904423
View directory record Official record
Conditions
Breast Cancer, Bone Diseases
Interventions
Vitamin D
Drug
Lead sponsor
Mark Pegram
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Jul 21, 2026, 4:56 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Soy Bread on Markers of Bone Metabolism and Cardiovascular Disease

NCT00366860
View directory record Official record
Conditions
Osteoporosis, Cardiovascular Diseases
Interventions
Soy bread
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced Jul 21, 2026, 4:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)

NCT03657589
View directory record Official record
Conditions
Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Jul 21, 2026, 4:56 AM EDT