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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Bone Mineral Density, Bone Strength
Interventions
LMHF mechanical stimulation active device, LMHF mechanical stimulation placebo device
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Spinal Cord Injury, Acute Spinal Cord Injury, Bone Loss, Osteoporosis
Interventions
Zoledronic acid, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Chicago, Illinois
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Doravirine and Weight Gain in Antiretroviral Naive

NCT05457530
Conditions
Body Weight Changes, Human Immunodeficiency Virus, ART, Obesity, Minority Health, BMD, Metabolic Syndrome, Fasting
Interventions
DOR/3TC/TDF, DOR + FTC/TAF, BIC/FTC/TAF
Drug · Combination Product
Lead sponsor
Prism Health North Texas
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of DHEA/Exercise on Bone, Muscle and Balance

NCT00664053
Conditions
Osteoporosis, Frailty
Interventions
DHEA, Yoga, Placebo, Aerobics
Dietary Supplement · Behavioral
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
65 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Osteoporosis, Renal Osteodystrophy, Kidney Transplant; Complications
Interventions
Denosumab Inj 60 mg/ml, Placebo
Drug · Other
Lead sponsor
Thomas Nickolas, MD MS
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Chicago, Illinois • Evanston, Illinois • New York, New York
Completed No phase listed Observational Accepts healthy volunteers

MACS and Healthy Volunteers Bone Study

NCT04343560
Conditions
MACS Syndrome
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Osteoporosis
Interventions
ibandronate, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
55 Years to 80 Years · Female only
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
14
States / cities
Upland, California • Boulder, Colorado • Lakewood, Colorado + 10 more
Not listed No phase listed Observational Accepts healthy volunteers

The Impact of Glomerular Disorders on Bone Quality and Strength

NCT04528446
Conditions
Glomerular Disease, Bone Diseases, Metabolic, Bone Fracture
Interventions
Dual-energy X-ray absorptiometry, High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT), Blood draw and Urine collection, Questionnaires
Radiation · Other
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 55 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Conditions
Arthritis, Juvenile
Interventions
Ren-Ex Machine, Dual-Emission X-ray Absorptiometry (DEXA) scan, Biodex dynamometer, Sub-maximal test, Quality of life questionnaires
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
10 Years to 21 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Total Knee Replacement, Arthroplasty, Patella
Interventions
Primary Total Knee Replacement Surgery
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoporosis
Interventions
ibandronate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
55 Years to 80 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
15
States / cities
Upland, California • Boulder, Colorado • Lakewood, Colorado + 11 more
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Bone Micro-Architecture Using HR-pQCT

NCT01367730
Conditions
Osteoporosis
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 85 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Francisco, California
Conditions
Older Adults, Bioelectrical Impedance, Appetite Hormones, Metabolic Health, Body Composition Measurement, Cognitive Health
Interventions
Synbiotic supplement
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Survivors of Bone Marrow Transplant, Autologous and Allogeneic
Interventions
Not listed
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
8 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Osteoporosis
Interventions
Exoskeleton assisted gait training
Device
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Englewood, Colorado
Conditions
Williams Syndrome, Lipedema
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Botox and Vibration on Bone in Children With Cerebral Palsy

NCT01803464
Conditions
Cerebral Palsy, Muscle Spasticity
Interventions
Low-magnitude vibration, Botox
Device · Drug
Lead sponsor
University of Delaware
Other
Eligibility
2 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
Newark, Delaware • Wilmington, Delaware
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training in Patients With Lower Extremity Fractures

NCT06496035
Conditions
Tibial Fractures, Lower Extremity Fracture
Interventions
Blood Flow Restriction with low load exercise, Therapeutic Exercise
Device · Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Denver, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Two Exercise Programs on Bone Strength and Architecture

NCT02636530
Conditions
Osteoporosis
Interventions
Ground Reaction Forces, Joint Reaction Forces
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
60 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myogenic and Osteogenic Responses to eXercise and Ibuprofen

NCT00462722
Conditions
Aging, Physical Fitness
Interventions
Ibuprofen, Placebo, musculoskeletal-loading exercise
Drug · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
60 Years to 75 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Completed No phase listed Observational Accepts healthy volunteers Results available

Effects of Exemestane on Bone Strength

NCT01144468
Conditions
Osteoporosis, Breast Cancer
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older · Female only
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2022
U.S. locations
2
States / cities
Sacramento, California • Rochester, Minnesota
Conditions
Breast Neoplasm, Osteoporosis, Postmenopausal
Interventions
Resistance Exercise, Flexibility Training
Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
50 Years to 90 Years · Female only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Unilateral Hip Fracture
Interventions
Self-efficacy and muscle strength training, High-intensity strength training
Behavioral · Procedure
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2000
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoporosis, Bone Fracture
Interventions
denosumab
Drug
Lead sponsor
HealthEast Care System
Other
Eligibility
40 Years to 90 Years · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Saint Paul, Minnesota