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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
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Conditions
Borderline Personality Disorder
Interventions
Systems Training for Emotional Predictability and Problem Solving (STEPPS), Treatment As Usual (TAU)
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 2 Interventional Results available

Brexpiprazole in Borderline Personality Disorder

NCT03418675
Conditions
Borderline Personality Disorder
Interventions
Rexulti, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Major Depressive Disorder, Dysthymia, Depression Not Otherwise Specified, Borderline Personality Disorder
Interventions
Lithium Carbonate, Placebo, Citalopram
Drug
Lead sponsor
Columbia Northwest Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
San Diego, California • Bellevue, Washington
Conditions
Borderline Personality Disorder, Alcohol Use Disorder
Interventions
Psychodynamic Therapy, Optimized Community Care
Behavioral
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Syracuse, New York
Conditions
Borderline Personality Disorder
Interventions
Acetaminophen
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Borderline Personality Disorder
Interventions
real time fMRI neurofeedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Not listed Not applicable Interventional

DBT in Borderline Personality Disorder

NCT00252031
Conditions
Borderline Personality Disorder
Interventions
Dialectical Behavioral Therapy
Behavioral
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
The Bronx, New York
Completed Phase 2 Interventional Results available

Caplyta in Borderline Personality Disorder

NCT05356013
Conditions
Borderline Personality Disorder
Interventions
Caplyta, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Borderline Personality Disorder
Interventions
Dialectical Behavior Therapy
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
1
States / cities
Piscataway, New Jersey
Recruiting Not applicable Interventional Accepts healthy volunteers

Affect-based Impulsivity in Borderline Personality Disorder

NCT06880640
Conditions
Borderline Personality Disorder (BPD), Healthy Controls Group - Age and Sex-matched
Interventions
Stress Induction
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Borderline Personality Disorder
Interventions
mifepristone, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Five Factor Model Treatment for Borderline Personality Disorder

NCT04587518
Conditions
Borderline Personality Disorder
Interventions
Personality-Based Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Borderline Personality Disorder, Suicide
Interventions
Standard dialectical behavior therapy (SDBT), Individual DBT with no DBT group sessions (DBT-I), Group Skills DBT with no DBT individual sessions (DBT-S)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Borderline Personality Disorder
Interventions
Brexpiprazole
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational Accepts healthy volunteers

fMRI in Impulsivity

NCT02755181
Conditions
Impulse Control Disorders, Borderline Personality Disorder
Interventions
Experimental
Behavioral
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Borderline Personality Disorder (BPD)
Interventions
TMS, D-Cycloserine (DCS)
Device · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Opiate Addiction, Borderline Personality Disorder
Interventions
Dialectical Behavior Therapy, Drug Counseling
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Attention Deficit Hyperactivity Disorder, Borderline Personality Disorder, Substance Use Disorders
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Borderline Personality Disorder
Interventions
creativity group
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Syracuse, New York
Conditions
Borderline Personality Disorder
Interventions
Countering Emotional Behaviors Module from Unified Protocol
Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Role Of Sensitivity to neuroEndocrine Systems in Social Decisions

NCT06018727
Conditions
Borderline Personality Disorder
Interventions
Hydrocortisone, Yohimbine, Placebo
Drug · Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Borderline Personality Disorder
Interventions
Supportive psychotherapy
Behavioral
Lead sponsor
Adams Clinical
Network
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Watertown, Massachusetts
Conditions
Borderline Personality Disorder
Interventions
Amygdala Neurofeedback
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Borderline Personality Disorder
Interventions
risperidone
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama