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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Function Clear all
Completed Phase 3 Interventional

Effect of Working Memory Training on ADHD Brain Function

NCT02151396
View directory record Official record
Conditions
Attention-Deficit/Hyperactivity Disorder (Combined-subtype)
Interventions
Working memory training, Functional magnetic resonance imaging (fMRI)
Behavioral · Device
Lead sponsor
Hartford Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 29, 2014 · Synced Jul 22, 2026, 9:31 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Entorhinal Cortex and Aerobic Exercise in Aging

NCT02775760
View directory record Official record
Conditions
Aging
Interventions
Cardiovascular endurance, Strength, balance, and flexibility
Behavioral
Lead sponsor
Boston University
Other
Eligibility
60 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jul 22, 2026, 9:31 PM EDT
Terminated No phase listed Observational

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

NCT01281982
View directory record Official record
Conditions
Low Grade Glioma, Glioblastoma Multiforme, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Oligoastrocytoma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Jul 22, 2026, 9:31 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder

NCT03307317
View directory record Official record
Conditions
Developmental Delay
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
9 Months to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Everyday Function Intervention Trial

NCT04651582
View directory record Official record
Conditions
Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
Interventions
Cognitive Training, Cognitive Stimulating Activities
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
65 Years to 90 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2023 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury

NCT00704379
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Placebo, Sertraline
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2015 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Brain Function and EEG

NCT05003076
View directory record Official record
Conditions
Healthy, Mood
Interventions
Methamphetamine, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional

Spinal Cord Stimulation for Restoration of Arm and Hand Function in People With Subcortical Stroke

NCT04512690
View directory record Official record
Conditions
Stroke, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions
Epidural electrical stimulation (EES) of the cervical spinal cord
Device
Lead sponsor
Lee Fisher, PhD
Other
Eligibility
21 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional

Personalized Post-Stroke Gait Rehabilitation Interventions

NCT07212608
View directory record Official record
Conditions
Stroke
Interventions
Soft robotic exosuit, Propulsion neuroprosthesis
Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jul 22, 2026, 9:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Enhancing Cognitive and Neurobehavioral Functions After Repetitive Traumatic Brain Injuries (rTBI) in Retired NFL Players and Military Veterans.

NCT02699476
View directory record Official record
Conditions
Traumatic Brain Injury, Concussion, Mild Cognitive Disorder
Interventions
Psycho-Social Therapy, Cognitive Behavioral Computer Training, Interactive Trainer-Subject Sessions, Active Control Games
Behavioral · Device
Lead sponsor
Brain & Body Health Foundation
Other
Eligibility
25 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lakeway, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Jul 22, 2026, 9:31 PM EDT
Completed No phase listed Observational

Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations

NCT00302146
View directory record Official record
Conditions
Parkinson Disease, Gaucher Disease
Interventions
15-0 H20
Drug
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 110 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 22, 2026, 9:31 PM EDT
Active, not recruiting Not applicable Interventional

Hand-Arm Bimanual Intensive Therapy in Virtual Reality Versus Standard Hand-Arm Bimanual Intensive Therapy

NCT05867368
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
HABIT-VR, Standard HABIT
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
6 Years to 16 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 22, 2026, 9:31 PM EDT
Recruiting No phase listed Observational

Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation

NCT07642908
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
45 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional

Innovative Modalities for Restoring Upper Limb Function Post Stroke

NCT01725659
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Motor Learning, Robotics, surface FES
Other
Lead sponsor
Malcom Randall VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2012 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feedback, Motor Sequence Learning, and Brain Connectivity

NCT04971486
View directory record Official record
Conditions
Adult
Interventions
Motor Sequence Task
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 40 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional Results available

rTMS to Improve Cognitive Function in TBI

NCT02152540
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
rTMS, Sham rTMS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Phase 4 Interventional

Predicting Stroke Risk in ICAD With Novel MRI

NCT05515874
View directory record Official record
Conditions
Intracranial Atherosclerosis
Interventions
Feraheme
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Not applicable Interventional Results available

Use of Joystick-operated Ride-on-toys to Improve Affected Arm Use and Function in Children With Hemiplegic Cerebral Palsy

NCT05559320
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
Ride-on-toy navigation training, Upper extremity functional training
Device · Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
3 Years to 8 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Jul 22, 2026, 9:31 PM EDT
Completed No phase listed Observational

Structural and Functional Neuroimaging Studies of Combat Veterans

NCT01296126
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Phase 4 Interventional Results available

Drug Treatment Validation of Functional Magnetic Resonance Imaging in Generalized Anxiety Disorder

NCT00662259
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Alprazolam (Xanax), Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Jul 22, 2026, 9:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex

NCT00024908
View directory record Official record
Conditions
Intracranial Central Nervous System Disorder, Mental Disorder, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
6 Years to 90 Years
Enrollment
949 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 9:31 PM EDT
Completed No phase listed Observational

Evaluation of the Effect of an Ankle Foot Orthoses for Ambulatory Function

NCT01336517
View directory record Official record
Conditions
Hemiplegia, Spastic
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 17, 2011 · Synced Jul 22, 2026, 9:31 PM EDT
Completed Phase 2 Interventional Results available

Extension of the MIME Robotic System for Stroke Rehabilitation

NCT00995774
View directory record Official record
Conditions
Stroke, Impaired Upper Extremity Function
Interventions
robotic therapy, conventional functional training
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Jul 22, 2026, 9:31 PM EDT
Completed No phase listed Observational Results available

Effects of Clobazam on Sleep and Daytime Function in Patients With Epilepsy

NCT02911025
View directory record Official record
Conditions
Epilepsy
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2021 · Synced Jul 22, 2026, 9:31 PM EDT